Related papers: Mixed integer programming improves comprehensibili…
We conduct a theoretical study of various solution methods for the adaptive fractionation problem. The two messages of this paper are: (i) dynamic programming (DP) is a useful framework for adaptive radiation therapy, particularly adaptive…
Purpose: To make the planning of volumetric modulated arc therapy (VMAT) faster and to explore the tradeoffs between planning objectives and delivery efficiency. Methods: A convex multicriteria dose optimization problem is solved for an…
The surgical department and adequate access to health care are critical problems. The operating room plays a fundamental role in the performance of a hospital. The real problem faces several issues to collect data and optimize scheduling…
Radiotherapy treatment planning currently requires many trail-and-error iterations between the planner and treatment planning system, as well as between the planner and physician for discussion/consultation. The physician's preferences for…
We propose a dual dynamic integer programming (DDIP) framework for solving multi-scale mixed-integer model predictive control (MPC) problems. Such problems arise in applications that involve long horizons and/or fine temporal…
Deep learning-based automated contouring and treatment planning has been proven to improve the efficiency and accuracy of radiotherapy. However, conventional radiotherapy treatment planning process has the automated contouring and treatment…
Abstract Objective. Cone-beam computed tomography is becoming more and more popular in applications such as 3D dental imaging. Iterative methods compared to the standard Feldkamp algorithm have shown improvements in image quality of…
The development of a digital twin (DT) framework for fast online adaptive proton therapy planning in prostate stereotactic body radiation therapy (SBRT) with dominant intraprostatic lesion (DIL) boost represents a significant advancement in…
Machine Reassignment is a challenging problem for constraint programming (CP) and mixed-integer linear programming (MILP) approaches, especially given the size of data centres. The multi-objective version of the Machine Reassignment Problem…
Proton pencil beam scanning (PBS) treatment planning for head & neck (H&N) cancers involves numerous conflicting objectives, requiring iterative objective parameter adjustments to balance multiple clinical goals. We propose a…
Finding optimal join orders is among the most crucial steps to be performed by query optimisers. Though extensively studied in data management research, the problem remains far from solved: While query optimisers rely on exhaustive search…
First-order primal-dual methods are appealing for their low memory overhead, fast iterations, and effective parallelization. However, they are often slow at finding high accuracy solutions, which creates a barrier to their use in…
Discrete black-box optimization problems are challenging for model-based optimization (MBO) algorithms, such as Bayesian optimization, due to the size of the search space and the need to satisfy combinatorial constraints. In particular,…
The purpose of this study is to give an exact formulation of optimization of volumetric-modulated arc therapy (VMAT) with sliding-window delivery, and to investigate the plan quality effects of decreasing the number of sliding-window sweeps…
We consider the problem of massive matrix multiplication, which underlies many data analytic applications, in a large-scale distributed system comprising a group of worker nodes. We target the stragglers' delay performance bottleneck, which…
Recent years have seen significant advances in quantum/quantum-inspired technologies capable of approximately searching for the ground state of Ising spin Hamiltonians. The promise of leveraging such technologies to accelerate the solution…
This work solves suboptimal mixed-integer quadratic programs recursively for feedback control of dynamical systems. The proposed framework leverages parametric mixed-integer quadratic programming (MIQP) and hybrid systems theory to model a…
Hyperparameter (HP) optimization of deep learning (DL) is essential for high performance. As DL often requires several hours to days for its training, HP optimization (HPO) of DL is often prohibitively expensive. This boosted the emergence…
We propose a hierarchical architecture for efficiently computing high-quality solutions to structured mixed-integer programs (MIPs). To reduce computational effort, our approach decouples the original problem into a higher level problem and…
Convex quadratic programs (QPs) are fundamental to numerous applications, including finance, engineering, and energy systems. Among the various methods for solving them, the Douglas-Rachford (DR) splitting algorithm is notable for its…