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We consider a two-component competition-diffusion system with equal diffusion coefficients and inhomogeneous Dirichlet boundary conditions. When the interspecific competition parameter tends to infinity, the system solution converges to…

Analysis of PDEs · Mathematics 2007-07-13 E. C. M. Crooks , E. N. Dancer , D. Hilhorst

Establishing sharp and correctly positioned boundaries in spatial gene expression patterns is a central task, both in developmental and synthetic biology. We consider situations where a global morphogen gradient provides positional…

Biological Physics · Physics 2022-06-09 Mareike Bojer , Stephan Kremser , Ulrich Gerland

We discovered a class of self-similar solutions in nonlinear models describing the formation of morphogen gradients, the concentration fields of molecules acting as spatial regulators of cell differention in developing tissues. These models…

Quantitative Methods · Quantitative Biology 2015-05-28 Cyrill B. Muratov , Peter V. Gordon , Stanislav Y. Shvartsman

In this paper we consider the diffusive competition model with free boundary in the heterogeneous time-periodic environment, in which the variable intrinsic growth rates of invasive and native species may change signs and be "very negative"…

Analysis of PDEs · Mathematics 2015-04-28 Mingxin Wang

We consider a partial differential equation model for the growth of heterogeneous cell populations subdivided into multiple distinct discrete phenotypes. In this model, cells preferentially move towards regions where they feel less…

Analysis of PDEs · Mathematics 2025-04-04 José A. Carrillo , Tommaso Lorenzi , Fiona R. Macfarlane

Understanding the rules underlying organismal development is a major unsolved problem in biology. Each cell in a developing organism responds to signals in its local environment by dividing, excreting, consuming, or reorganizing, yet how…

Cell Behavior · Quantitative Biology 2025-08-20 Ramya Deshpande , Francesco Mottes , Ariana-Dalia Vlad , Michael P. Brenner , Alma dal Co

In this paper, we study stochastic homogenization of a coupled diffusion-reaction system. The diffusion-reaction system is coupled to stochastic differential equations, which govern the changes in the media properties. Though homogenization…

Probability · Mathematics 2018-10-18 Hakima Bessaih , Yalchin Efendiev , Razvan Florian Maris

Using a microscopic phase-space model of the membrane system, the boundary condition at a membrane is derived. According to the condition, the substance flow across the membrane is proportional to the difference of the substance…

Condensed Matter · Physics 2007-05-23 Tadeusz Kosztolowicz , Stanislaw Mrowczynski

We consider a particle transport process in a one-dimensional system with a thin membrane, described by a normal diffusion equation. We consider two boundary conditions at the membrane that are linear combinations of integral operators,…

Statistical Mechanics · Physics 2022-05-24 Tadeusz Kosztołowicz , Aldona Dutkiewicz

Computational modelling of diffusion in heterogeneous media is prohibitively expensive for problems with fine-scale heterogeneities. A common strategy for resolving this issue is to decompose the domain into a number of non-overlapping…

Computational Physics · Physics 2021-08-26 Nathan G. March , Elliot J. Carr , Ian W. Turner

We consider a model for a population in a heterogeneous environment, with logistic type local population dynamics, under the assumption that individuals can switch between two different nonzero rates of diffusion. Such switching behavior…

Analysis of PDEs · Mathematics 2020-01-14 Robert Stephen Cantrell , Chris Cosner , Xiao Yu

This paper deals with the long-time behavior of solutions of nonlinear reaction-diffusion equations describing formation of morphogen gradients, the concentration fields of molecules acting as spatial regulators of cell differentiation in…

Analysis of PDEs · Mathematics 2013-03-27 Peter V. Gordon , Cyrill B. Muratov

A mass transport directed from low to high density region in an inhomogeneous medium is modeled as a limiting case of a two-component lattice gas with excluded volume constraint and one of the components fixed. In the long-wavelength…

Disordered Systems and Neural Networks · Physics 2012-10-05 Sergei P. Lukyanets , Oleksandr V. Kliushnychenko

A one-dimensional cross-diffusion system modeling the transport of vesicles in neurites is analyzed. The equations are coupled via nonlinear Robin boundary conditions to ordinary differential equations for the number of vesicles in the…

Analysis of PDEs · Mathematics 2023-05-25 Markus Fellner , Ansgar Jüngel

We consider a stochastically perturbed reaction diffusion equation in a bounded interval, with boundary conditions imposing the two stable phases at the endpoints. We investigate the asymptotic behavior of the front separating the two…

Mathematical Physics · Physics 2016-02-11 L. Bertini , S. Brassesco , P. Buttà

Based on a recently proposed non-equilibrium mechanism for spatial pattern formation [cond-mat/0312366] we study how morphogenesis can be controlled by locally coupled discrete dynamical networks, similar to gene regulation networks of…

Molecular Networks · Quantitative Biology 2007-05-23 Thimo Rohlf , Stefan Bornholdt

In this paper, we study the dynamics of a two-species competition model with two different free boundaries in heterogeneous time-periodic environment, where the two species adopt a combination of random movement and advection upward or…

Analysis of PDEs · Mathematics 2015-11-26 Qiaoling Chen , Fengquan Li , Feng Wang

Our investigation is specially motivated by the stochastic version of a common model of potential spread in a dendritic tree. We do not assume the noise in the junction points to be Markovian. In fact, we allow for long-range dependence in…

Probability · Mathematics 2018-12-21 Stefano Bonaccorsi , Delio Mugnolo

The interactions between diffusing molecules and membrane-bound receptors drive numerous cellular processes. In this work, we develop a spatial model of molecular interactions with membrane receptors by homogenizing the cell membrane and…

Quantitative Methods · Quantitative Biology 2025-01-24 Anil Cengiz , Sean D Lawley

The analysis and homogenization of a moving boundary problem for a highly heterogeneous, periodic two-phase medium is considered. In this context, the normal velocity governing the motion of the interface separating the two competing phases…

Analysis of PDEs · Mathematics 2019-01-09 Michael Eden
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