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Background: The computation of the statistical properties of motif occurrences has an obviously relevant practical application: for example, patterns that are significantly over- or under-represented in the genome are interesting candidates…

Genomics · Quantitative Biology 2021-11-01 Paolo Ribeca , Emanuele Raineri

Combining Bayesian nonparametrics and a forward model selection strategy, we construct parsimonious Bayesian deep networks (PBDNs) that infer capacity-regularized network architectures from the data and require neither cross-validation nor…

Machine Learning · Statistics 2019-01-03 Mingyuan Zhou

Real-world problems often involve the optimization of several objectives under multiple constraints. An example is the hyper-parameter tuning problem of machine learning algorithms. In particular, the minimization of the estimation of the…

Machine Learning · Statistics 2021-07-02 Eduardo C. Garrido-Merchán , Daniel Hernández-Lobato

Computational protein structure determination involves optimization in a problem space much too large to exhaustively search. Existing approaches include optimization algorithms such as gradient descent and simulated annealing, but these…

Distributed, Parallel, and Cluster Computing · Computer Science 2020-08-04 Michael Bryson , Xijiang Miao , Homayoun Valafar

Evolutionary computing, particularly genetic algorithm (GA), is a combinatorial optimization method inspired by natural selection and the transmission of genetic information, which is widely used to identify optimal solutions to complex…

Neural and Evolutionary Computing · Computer Science 2024-12-31 Shanqing Yu , Meng Zhou , Jintao Zhou , Minghao Zhao , Yidan Song , Yao Lu , Zeyu Wang , Qi Xuan

Motif searching is an important step in the detection of rare events occurring in a set of DNA or protein sequences. One formulation of the problem is known as (l,d)-motif search or Planted Motif Search (PMS). In PMS we are given two…

Data Structures and Algorithms · Computer Science 2013-07-03 Marius Nicolae , Sanguthevar Rajasekaran

This paper studies the problem of finding an $(1+\epsilon)$-approximate solution to positive semidefinite programs. These are semidefinite programs in which all matrices in the constraints and objective are positive semidefinite and all…

Data Structures and Algorithms · Computer Science 2016-02-23 Richard Peng , Kanat Tangwongsan , Peng Zhang

A novel unified Bayesian framework for network detection is developed, under which a detection algorithm is derived based on random walks on graphs. The algorithm detects threat networks using partial observations of their activity, and is…

Social and Information Networks · Computer Science 2014-09-09 Steven T. Smith , Edward K. Kao , Kenneth D. Senne , Garrett Bernstein , Scott Philips

This paper describes a new algorithm for exact Bayesian inference that is based on a recently proposed compositional semantics of Bayesian networks in terms of channels. The paper concentrates on the ideas behind this algorithm, involving a…

Artificial Intelligence · Computer Science 2018-04-24 Bart Jacobs

Bayesian networks (BNs) are graphical models that are useful for representing high-dimensional probability distributions. There has been a great deal of interest in recent years in the NP-hard problem of learning the structure of a BN from…

Machine Learning · Statistics 2016-10-04 D. Jennings , J. N. Corcoran

Hierarchical clustering is a fundamental task often used to discover meaningful structures in data, such as phylogenetic trees, taxonomies of concepts, subtypes of cancer, and cascades of particle decays in particle physics. Typically…

Data Structures and Algorithms · Computer Science 2020-10-23 Craig S. Greenberg , Sebastian Macaluso , Nicholas Monath , Ji-Ah Lee , Patrick Flaherty , Kyle Cranmer , Andrew McGregor , Andrew McCallum

In this paper, we describe efficient MapReduce simulations of parallel algorithms specified in the BSP and PRAM models. We also provide some applications of these simulation results to problems in parallel computational geometry for the…

Data Structures and Algorithms · Computer Science 2015-03-14 Michael T. Goodrich

Finding dense subgraphs is a fundamental algorithmic tool in data mining, community detection, and clustering. In this problem, one aims to find an induced subgraph whose edge-to-vertex ratio is maximized. We study the directed case of this…

Data Structures and Algorithms · Computer Science 2023-11-21 Slobodan Mitrović , Theodore Pan

Recently, there has been much interest in finding globally optimal Bayesian network structures. These techniques were developed for generative scores and can not be directly extended to discriminative scores, as desired for classification.…

Machine Learning · Computer Science 2012-07-03 Robert Peharz , Franz Pernkopf

The aim of this paper is to show that Digital Signal Processors (DSPs) can be used to efficiently implement complex algorithms. As an example we have chosen the problem of enumerating closed two-dimensional random paths. An Evaluation…

Computational Physics · Physics 2007-05-23 B. Afsari , N. Sadeghi-Meybodi , S. Rouhani

A common way to accelerate shortest path algorithms on graphs is the use of a bidirectional search, which simultaneously explores the graph from the start and the destination. It has been observed recently that this strategy performs…

Data Structures and Algorithms · Computer Science 2022-03-17 Thomas Bläsius , Cedric Freiberger , Tobias Friedrich , Maximilian Katzmann , Felix Montenegro-Retana , Marianne Thieffry

Constructing a Depth First Search (DFS) tree is a fundamental graph problem, whose parallel complexity is still not settled. Reif showed parallel intractability of lex-first DFS. In contrast, randomized parallel algorithms (and more…

Data Structures and Algorithms · Computer Science 2025-10-09 Archit Chauhan , Samir Datta , M. Praveen

Background: Clustering of nodes in Bayesian Networks (BNs) and related graphical models such as Dynamic BNs (DBNs) has been demonstrated to enhance computational efficiency and improve model learning. It typically involves partitioning the…

Data Structures and Algorithms · Computer Science 2025-12-24 Paul Pao-Yen Wu , Fabrizio Ruggeri , Kerrie Mengersen

Bayesian network structure learning is often performed in a Bayesian setting, evaluating candidate structures using their posterior probabilities for a given data set. Score-based algorithms then use those posterior probabilities as an…

Machine Learning · Statistics 2017-04-14 Marco Scutari

Despite rapid progress in the development of quantum algorithms in quantum computing as well as numerical simulation methods in classical computing for atomic and molecular applications, no systematic and comprehensive electronic structure…