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We show an essentially tight bound on the number of adaptively chosen statistical queries that a computationally efficient algorithm can answer accurately given $n$ samples from an unknown distribution. A statistical query asks for the…

Cryptography and Security · Computer Science 2015-02-23 Thomas Steinke , Jonathan Ullman

A great deal of effort has been devoted to reducing the risk of spurious scientific discoveries, from the use of sophisticated validation techniques, to deep statistical methods for controlling the false discovery rate in multiple…

Machine Learning · Computer Science 2016-03-03 Cynthia Dwork , Vitaly Feldman , Moritz Hardt , Toniann Pitassi , Omer Reingold , Aaron Roth

Adaptivity is an important feature of data analysis---typically the choice of questions asked about a dataset depends on previous interactions with the same dataset. However, generalization error is typically bounded in a non-adaptive…

Machine Learning · Computer Science 2015-11-11 Raef Bassily , Adam Smith , Thomas Steinke , Jonathan Ullman

Adaptivity is an important feature of data analysis---the choice of questions to ask about a dataset often depends on previous interactions with the same dataset. However, statistical validity is typically studied in a nonadaptive model,…

Machine Learning · Computer Science 2015-11-10 Raef Bassily , Kobbi Nissim , Adam Smith , Thomas Steinke , Uri Stemmer , Jonathan Ullman

The study of adaptive data analysis examines how many statistical queries can be answered accurately using a fixed dataset while avoiding false discoveries (statistically inaccurate answers). In this paper, we tackle a question that…

Machine Learning · Computer Science 2023-02-09 Roi Livni

Modern data workflows are inherently adaptive, repeatedly querying the same dataset to refine and validate sequential decisions, but such adaptivity can lead to overfitting and invalid statistical inference. Adaptive Data Analysis (ADA)…

Machine Learning · Computer Science 2026-02-10 Joon Suk Huh

We provide an approach to exploratory data analysis in matched observational studies with a single intervention and multiple endpoints. In such settings, the researcher would like to explore evidence for actual treatment effects among these…

Methodology · Statistics 2025-12-10 Mengqi Lin , Colin Fogarty

Traditional statistical analysis requires that the analysis process and data are independent. By contrast, the new field of adaptive data analysis hopes to understand and provide algorithms and accuracy guarantees for research as it is…

Machine Learning · Computer Science 2017-03-22 Sam Elder

Adaptive data analysis has posed a challenge to science due to its ability to generate false hypotheses on moderately large data sets. In general, with non-adaptive data analyses (where queries to the data are generated without being…

Methodology · Statistics 2018-09-18 Preetum Nakkiran , Jarosław Błasiok

Recent advances in generative models facilitate the creation of synthetic data to be made available for research in privacy-sensitive contexts. However, the analysis of synthetic data raises a unique set of methodological challenges. In…

As artificial intelligence and machine learning tools become more accessible, and scientists face new obstacles to data collection (e.g., rising costs, declining survey response rates), researchers increasingly use predictions from…

Machine Learning · Statistics 2025-12-08 Stephen Salerno , Kentaro Hoffman , Awan Afiaz , Anna Neufeld , Tyler H. McCormick , Jeffrey T. Leek

We present a new adaptive algorithm for learning discrete distributions under distribution drift. In this setting, we observe a sequence of independent samples from a discrete distribution that is changing over time, and the goal is to…

Machine Learning · Computer Science 2024-03-11 Alessio Mazzetto

In many scientific settings there is a need for adaptive experimental design to guide the process of identifying regions of the search space that contain as many true positives as possible subject to a low rate of false discoveries (i.e.…

Machine Learning · Statistics 2020-08-18 Lalit Jain , Kevin Jamieson

We propose an adaptive sampling approach for multiple testing which aims to maximize statistical power while ensuring anytime false discovery control. We consider $n$ distributions whose means are partitioned by whether they are below or…

Machine Learning · Statistics 2019-07-18 Kevin Jamieson , Lalit Jain

Ensuring that analyses performed on a dataset are representative of the entire population is one of the central problems in statistics. Most classical techniques assume that the dataset is independent of the analyst's query and break down…

Machine Learning · Computer Science 2024-09-25 Guy Blanc

We consider a model of selective prediction, where the prediction algorithm is given a data sequence in an online fashion and asked to predict a pre-specified statistic of the upcoming data points. The algorithm is allowed to choose when to…

Machine Learning · Computer Science 2019-05-30 Mingda Qiao , Gregory Valiant

Causal discovery from interventional data is an important problem, where the task is to design an interventional strategy that learns the hidden ground truth causal graph $G(V,E)$ on $|V| = n$ nodes while minimizing the number of performed…

Machine Learning · Computer Science 2023-06-12 Davin Choo , Kirankumar Shiragur

We investigate distribution testing with access to non-adaptive conditional samples. In the conditional sampling model, the algorithm is given the following access to a distribution: it submits a query set $S$ to an oracle, which returns a…

Data Structures and Algorithms · Computer Science 2018-11-06 Gautam Kamath , Christos Tzamos

We develop methods for forming prediction sets in an online setting where the data generating distribution is allowed to vary over time in an unknown fashion. Our framework builds on ideas from conformal inference to provide a general…

Methodology · Statistics 2021-12-10 Isaac Gibbs , Emmanuel Candès

When domain knowledge is limited and experimentation is restricted by ethical, financial, or time constraints, practitioners turn to observational causal discovery methods to recover the causal structure, exploiting the statistical…

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