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We consider two volume-surface reaction-diffusion systems arising from cell biology. The first system describes the localisation of the protein Lgl in the asymmetric division of Drosophila SOP stem cells, while the second system models the…

Analysis of PDEs · Mathematics 2016-12-22 Klemens Fellner , Bao Quoc Tang

We consider the numerical solution of coupled volume-surface reaction-diffusion systems having a detailed balance equilibrium. Based on the conservation of mass, an appropriate quadratic entropy functional is identified and an…

Numerical Analysis · Mathematics 2015-11-04 Herbert Egger , Klemens Fellner , Jan-Frederik Pietschmann , Bao Quoc Tang

Lattice-based stochastic simulators are commonly used to study biological reaction-diffusion processes. Some of these schemes that are based on the reaction-diffusion master equation (RDME), can simulate for extended spatial and temporal…

Quantitative Methods · Quantitative Biology 2018-10-03 Wei-Xiang Chew , Kazunari Kaizu , Masaki Watabe , Sithi V. Muniandy , Koichi Takahashi , Satya N. V. Arjunan

Microscopic models of reaction-diffusion processes on the cell membrane can link local spatiotemporal effects to macroscopic self-organized patterns often observed on the membrane. Simulation schemes based on the microscopic lattice method…

Subcellular Processes · Quantitative Biology 2019-04-24 Wei-Xiang Chew , Kazunari Kaizu , Masaki Watabe , Sithi V. Muniandy , Koichi Takahashi , Satya N. V. Arjunan

We consider a model system consisting of two reaction-diffusion equations, where one species diffuses in a volume while the other species diffuses on the surface which surrounds the volume. The two equations are coupled via a nonlinear…

Analysis of PDEs · Mathematics 2017-07-21 Tang Quoc Bao , Klemens Fellner , Evangelos Latos

Motivated by models of signaling pathways in B lymphocytes, which have extremely large nuclei, we study the question of how reaction-diffusion equations in thin $2D$ domains may be approximated by diffusion equations in regions of smaller…

Analysis of PDEs · Mathematics 2020-07-17 Adam Bobrowski

Protein aggregation on the plasma membrane (PM) is of critical importance to many cellular processes such as cell adhesion, endocytosis, fibrillar conformation, and vesicle transport. Lateral diffusion of protein aggregates or clusters on…

Subcellular Processes · Quantitative Biology 2019-08-15 L. M. Stolerman , M. Getz , S. G. Llewellyn Smith , M. Holst , P. Rangamani

Understanding the asymptotic behavior of reaction-diffusion (RD) systems is crucial for modeling processes ranging from species coexistence in ecology to biochemical interactions within cells. In this work, we analyze RD systems in which…

Dynamical Systems · Mathematics 2025-02-18 Carlos Barajas , Jean-Jacques Slotine , Domitilla Del Vecchio

We present and analyse a model for cell signalling processes in biological tissues. The model includes diffusion and nonlinear reactions on the cell surfaces, and both inter- and intracellular signalling. Using techniques from the theory of…

Analysis of PDEs · Mathematics 2020-03-12 Mariya Ptashnyk , Chandrasekhar Venkataraman

Various biological cells secrete diffusing chemical compounds into their environment for communication purposes. Secretion usually takes place over the cell membrane in a spatially heterogeneous manner. Mathematical models of these…

Numerical Analysis · Mathematics 2025-11-20 Qiyao Peng , Sander C. Hille

We study the Schloegl model in a vesicle with semi-permeable membrane. The diffusion constant takes a smaller value in the membrane region, which prevents the outflow of self-catalytic product. A nonequilibrium state is stably maintained…

Statistical Mechanics · Physics 2009-11-11 Hidetsugu Sakaguchi

Lateral diffusion of molecules on surfaces plays a very important role in various biological processes, including lipid transport across the cell membrane, synaptic transmission and other phenomena such as exo- and endocytosis, signal…

Analysis of PDEs · Mathematics 2013-11-12 A. B. Duncan , C. M. Elliott , G. A. Pavliotis , A. M. Stuart

We study the global existence of classical solutions to volume-surface reaction-diffusion systems with control of mass. Such systems appear naturally from modeling evolution of concentrations or densities appearing both in a volume domain…

Analysis of PDEs · Mathematics 2021-01-21 Jeff Morgan , Bao Quoc Tang

In this study, we prove results on the weak solvability and homogenization of a microscopic semi-linear elliptic system posed in perforated media. The model presented here explores the interplay between stationary diffusion and both surface…

Analysis of PDEs · Mathematics 2016-03-15 Vo Anh Khoa , Adrian Muntean

Diffusion within porous media, such as biological tissues, exhibits departures from conventional Fick's laws, which could result in space-fractional diffusion. The paper considers a reaction-diffusion system with two spatial compartments --…

General Mathematics · Mathematics 2025-11-12 Dimiter Prodanov

We study the weak solvability of a quasilinear reaction-diffusion system nonlinearly coupled with an linear elliptic system posed in a domain with distributed microscopic balls in $2D$. The size of these balls are governed by an ODE with…

Analysis of PDEs · Mathematics 2023-11-23 Michael Eden , Christos Nikolopoulos , Adrian Muntean

Communication between single cells or higher organisms by means of diffusive compounds is an important phenomenon in biological systems. Modelling therefore often occurs, most straightforwardly by a diffusion equation with suitable flux…

Analysis of PDEs · Mathematics 2025-05-19 Xiao Yang , Qiyao Peng , Sander C. Hille

In this work, the asymptotic state of nonlinear Landau damping in one-dimensional plasma has been examined using a quasi-linear model and a second-order symplectic integrator. The dispersion relation of the plateau distribution function for…

Plasma Physics · Physics 2025-12-22 Yifei Ouyang , Ping Zhu , Chung-Sang Ng

We consider deterministic dynamics, known as the slicer map (SM), which exhibits normal and anomalous diffusion by varying a single parameter. The statistics of the position moments and the low-order position autocorrelation function (PACF)…

Statistical Mechanics · Physics 2025-08-19 Muhammad Tayyab , Jahanzeb Tariq

In this paper, we study a numerical approximation for a class of stationary states for reaction-diffusion system with m densities having disjoint support, which are governed by a minimization problem. We use quantitative properties of both…

Numerical Analysis · Mathematics 2014-05-09 Avetik Arakelyan , Farid Bozorgnia
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