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Epidemiologists commonly use regional aggregates of health outcomes to map mortality or incidence rates and identify geographic disparities. However, to detect health disparities across regions, it is necessary to identify "difference…

Methodology · Statistics 2025-05-14 Luca Aiello , Sudipto Banerjee

Regional aggregates of health outcomes over delineated administrative units (e.g., states, counties, zip codes), or areal units, are widely used by epidemiologists to map mortality or incidence rates and capture geographic variation. To…

Methodology · Statistics 2022-05-03 Leiwen Gao , Sudipto Banerjee , Beate Ritz

When assessing the short term effect of air pollution on health outcomes, it is common practice to consider one pollutant at a time, due to their high correlation. Multi pollutant methods have been recently proposed, mainly consisting of…

Applications · Statistics 2019-06-19 Marta Blangiardo , Monica Pirani , Lauren Kanapka , Anna Hansell , Gary Fuller

Our method extends the application of random spanning trees to cases where the response variable belongs to the exponential family, making it suitable for a wide range of real-world scenarios, including non-Gaussian likelihoods. The…

Methodology · Statistics 2024-07-18 Ruiman Zhong , Erick A. Chacón-Montalván , Paula Moraga

Recent advances in multiplex imaging have enabled researchers to locate different types of cells within a tissue sample. This is especially relevant for tumor immunology, as clinical regimes corresponding to different stages of disease or…

Improving health worldwide will require rigorous quantification of population-level trends in health status. However, global-level surveys are not available, forcing researchers to rely on fragmentary country-specific data of varying…

Methodology · Statistics 2014-05-20 Mariel M. Finucane , Christopher J. Paciorek , Goodarz Danaei , Majid Ezzati

In economic development, there are often regions that share similar economic characteristics, and economic models on such regions tend to have similar covariate effects. In this paper, we propose a Bayesian clustered regression for…

Econometrics · Economics 2020-06-30 Zhihua Ma , Yishu Xue , Guanyu Hu

Spatial statistical models are commonly used in geographical scenarios to ensure spatial variation is captured effectively. However, spatial models and cluster algorithms can be complicated and expensive. This paper pursues three main…

The analysis of population-wide datasets can provide insight on the health status of large populations so that public health officials can make data-driven decisions. The analysis of such datasets often requires highly parameterized models…

Applications · Statistics 2021-02-03 Dorota Młynarczyk , Carmen Armero , Virgilio Gómez-Rubio , Pedro Puig

Mapping of spatial hotspots, i.e., regions with significantly higher rates of generating cases of certain events (e.g., disease or crime cases), is an important task in diverse societal domains, including public health, public safety,…

Machine Learning · Statistics 2021-10-12 Yiqun Xie , Shashi Shekhar , Yan Li

In epidemiological studies of air pollution and public health, estimating the health impact of exposure to air pollution may be hindered by the unknown functional form of the exposure-outcome association and by unmeasured confounding…

Methodology · Statistics 2026-01-28 Carlo Zaccardi , Pasquale Valentini , Luigi Ippoliti , Alexandra M. Schmidt

In the presence of unmeasured spatial confounding, spatial models may actually increase (rather than decrease) bias, leading to uncertainty as to how they should be applied in practice. We evaluated spatial modeling approaches through…

We propose a Bayesian approach for model-based clustering of multivariate categorical data where variables are allowed to be associated within clusters and the number of clusters is unknown. The approach uses a two-layer mixture of finite…

Methodology · Statistics 2024-07-09 Gertraud Malsiner-Walli , Bettina Grün , Sylvia Frühwirth-Schnatter

The health impact of long-term exposure to air pollution is now routinely estimated using spatial ecological studies, due to the recent widespread availability of spatial referenced pollution and disease data. However, this areal unit study…

Applications · Statistics 2014-12-16 Duncan Lee , Christophe Sarran

Cluster randomized trials (CRTs) offer a practical alternative for addressing logistical challenges and ensuring feasibility in community health, education, and prevention studies, even though randomized controlled trials are considered the…

Methodology · Statistics 2025-10-30 Jooyeon Lee , M. S. , Evan Kwiatkowski , Ph. D

We consider the problem of analyzing multivariate time series collected on multiple subjects, with the goal of identifying groups of subjects exhibiting similar trends in their recorded measurements over time as well as time-varying groups…

Traditional epidemic detection algorithms make decisions using only local information. We propose a novel approach that explicitly models spatial information fusion from several metapopulations. Our method also takes into account…

Computation · Statistics 2015-09-15 Michael Ludkovski , Katherine Shatskikh

In this study, we propose a novel application of spatiotemporal clustering in the environmental sciences, with a particular focus on regionalised time series of greenhouse gases (GHGs) emissions from a range of economic sectors. Utilising a…

Applications · Statistics 2025-03-18 Caterina Morelli , Paolo Maranzano , Philipp Otto

With the advance of imaging technology, digital pathology imaging of tumor tissue slides is becoming a routine clinical procedure for cancer diagnosis. This process produces massive imaging data that capture histological details in high…

Methodology · Statistics 2020-12-10 Qiwei Li , Xinlei Wang , Faming Liang , Guanghua Xiao

Prevalence mapping in low resource settings is an increasingly important endeavor to guide policy making and to spatially and temporally characterize the burden of disease. We will focus our discussion on consideration of the complex design…

Methodology · Statistics 2016-08-15 Jon Wakefield , Daniel Simpson , Jessica Godwin