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Related papers: Estimating Clonality

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In consensus clustering, a clustering algorithm is used in combination with a subsampling procedure to detect stable clusters. Previous studies on both simulated and real data suggest that consensus clustering outperforms native algorithms.…

In this work, we study diversity-aware clustering problems where the data points are associated with multiple attributes resulting in intersecting groups. A clustering solution needs to ensure that the number of chosen cluster centers from…

Data Structures and Algorithms · Computer Science 2025-05-21 Suhas Thejaswi , Ameet Gadekar , Bruno Ordozgoiti , Aristides Gionis

Studies of T cells and their clonally unique receptors have shown promise in elucidating the association between immune response and human disease. Methods to identify T-cell receptor clones which expand or contract in response to certain…

Methodology · Statistics 2025-02-10 David Swanson , Alexander Sherry , Chad Tang

Measuring dataset similarity is fundamental in machine learning, particularly for transfer learning and domain adaptation. In the context of supervised learning, most existing approaches quantify similarity of two data sets based on their…

Machine Learning · Statistics 2026-04-22 Shudong Sun , Hao Helen Zhang , Joseph C Watkins

Clustering, a fundamental activity in unsupervised learning, is notoriously difficult when the feature space is high-dimensional. Fortunately, in many realistic scenarios, only a handful of features are relevant in distinguishing clusters.…

Machine Learning · Statistics 2020-10-23 Zhiyue Zhang , Kenneth Lange , Jason Xu

The application of code clone technology accelerates code search, improves code reuse efficiency, and assists in software quality assessment and code vulnerability detection. However, the application of code clones also introduces software…

Software Engineering · Computer Science 2022-02-18 Xunhui Zhang , Tao Wang , Yue Yu , Yanzhi Zhang , Yan Zhong , Huaimin Wang

Rapid technological advances have allowed for molecular profiling across multiple omics domains from a single sample for clinical decision making in many diseases, especially cancer. As tumor development and progression are dynamic…

Methodology · Statistics 2022-02-11 Dongyan Yan , Subharup Guha

Clustering algorithms are often used to find subpopulations in exploratory data analysis workflows. Not only the clusters themselves, but also their shape can represent meaningful subpopulations. In this paper, we present FLASC, an…

Machine Learning · Computer Science 2025-04-23 D. M. Bot , J. Peeters , J. Liesenborgs , J. Aerts

Clustering is a concept used in a huge variety of applications. We review a conceptually very simple algorithm for hierarchical clustering called in the following the {\it mutual information clustering} (MIC) algorithm. It uses mutual…

Quantitative Methods · Quantitative Biology 2008-09-10 Alexander Kraskov , Peter Grassberger

Most density based stream clustering algorithms separate the clustering process into an online and offline component. Exact summarized statistics are being employed for defining micro-clusters or grid cells during the online stage followed…

Databases · Computer Science 2016-12-09 Andrei Sorin Sabau

We introduce a new method for performing clustering with the aim of fitting clusters with different scatters and weights. It is designed by allowing to handle a proportion $\alpha$ of contaminating data to guarantee the robustness of the…

Statistics Theory · Mathematics 2008-12-18 Luis A. García-Escudero , Alfonso Gordaliza , Carlos Matrán , Agustin Mayo-Iscar

This paper is an extensive survey of literature on complex network communities and clustering. Complex networks describe a widespread variety of systems in nature and society especially systems composed by a large number of highly…

Social and Information Networks · Computer Science 2015-03-24 Biswajit Saha , Amitabha Mandal , Soumendu Bikas Tripathy , Debaprasad Mukherjee

The rapid emergence of high-dimensional data in various areas has brought new challenges to current ensemble clustering research. To deal with the curse of dimensionality, recently considerable efforts in ensemble clustering have been made…

Machine Learning · Computer Science 2021-09-07 Dong Huang , Chang-Dong Wang , Jian-Huang Lai , Chee-Keong Kwoh

In this paper, we consider the problem of partitioning a small data sample of size $n$ drawn from a mixture of $2$ sub-gaussian distributions. Our work is motivated by the application of clustering individuals according to their population…

Statistics Theory · Mathematics 2023-01-05 Shuheng Zhou

Clustering is a popular unsupervised learning tool often used to discover groups within a larger population such as customer segments, or patient subtypes. However, despite its use as a tool for subgroup discovery and description - few…

Machine Learning · Computer Science 2021-12-13 Connor Lawless , Jayant Kalagnanam , Lam M. Nguyen , Dzung Phan , Chandra Reddy

Comparing clusterings is central to evaluating unsupervised models, yet the many existing similarity measures can produce widely divergent, sometimes contradictory, evaluations. Clustering similarity measures are typically organized into…

Machine Learning · Statistics 2025-11-06 Alexander J. Gates

Biological tools such as genetic lineage tracing, three dimensional confocal microscopy and next generation DNA sequencing are providing new ways to quantify the distribution of clones of normal and mutated cells. Population-wide clone size…

Quantitative Methods · Quantitative Biology 2013-11-25 Roshan A , Jones PH , Greenman CD

Clustering data objects into homogeneous groups is one of the most important tasks in data mining. Spectral clustering is arguably one of the most important algorithms for clustering, as it is appealing for its theoretical soundness and is…

Machine Learning · Statistics 2024-03-12 Dylan Soemitro , Jeova Farias Sales Rocha Neto

Spatial models where growth is limited to the edge of the expansions have been instrumental to understand the population dynamics and the clone size distribution in growing cellular populations, such as microbial colonies and avascular…

Populations and Evolution · Quantitative Biology 2022-06-08 Armin Eghdami , Jayson Paulose , Diana Fusco

Cluster analysis relates to the task of assigning objects into groups which ideally present some desirable characteristics. When a cluster structure is confined to a subset of the feature space, traditional clustering techniques face…

Machine Learning · Statistics 2026-04-14 Efthymios Costa , Ioanna Papatsouma , Angelos Markos
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