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Recently, several studies have investigated the transcription process associated to specific genetic regulatory networks. In this work, we present a stochastic approach for analyzing the dynamics and effect of negative feedback loops (FBL)…
This paper studies exponential stability properties of a class of two-dimensional (2D) systems called differential repetitive processes (DRPs). Since a distinguishing feature of DRPs is that the problem domain is bounded in the "time"…
Transcription factor binding sites vary in their specificity, both within and between species. Binding specificity has a strong impact on the evolution of gene expression, because it determines how easily regulatory interactions are gained…
The complete analysis of a model with three quartic coupling constants associated with an O(2N)--symmetric, a cubic, and a tetragonal interactions is carried out within the three-loop approximation of the renormalization-group (RG) approach…
Impedance-based stability analysis is appealing in the case of Single-Input Single-Output (SISO) systems. However, in the case of grid-tied voltage source converter (VSC) systems, dq impedances of source and load (VSC) subsystems are…
Boolean networks have been proposed as potentially useful models for genetic control. An important aspect of these networks is the stability of their dynamics in response to small perturbations. Previous approaches to stability have assumed…
A field-theoretic description of the critical behaviour of the weakly disordered systems is given. Directly, for three- and two-dimensional systems a renormalization analysis of the effective Hamiltonian of model with replica symmetry…
This paper investigates the local asymptotic stabilization of a very general class of instable autonomous nonlinear difference equations which are subject to perturbed dynamics which can have a different order that that of the nominal…
The interactions between proteins, DNA, and RNA in living cells constitute molecular networks that govern various cellular functions. To investigate the global dynamical properties and stabilities of such networks, we studied the cell-cycle…
Modern power system is undergoing a paradigm shift from the synchronous generators-based system to the power electronics converters-dominated system. With the high penetration of converters, serious stability problems are provoked,…
The nucleotide sequence representation of DNA can be inadequate for resolving protein-DNA binding sites and regulatory substrates, such as those involved in gene expression and horizontal gene transfer. Considering that sequence-like…
Gene Regulatory Networks(GRNs) with feedback are essential components of many cellular processes and may exhibit oscillatory behavior. Analyzing such systems becomes increasingly complex as the number of components increases. Since gene…
We model the phase oscillations of electrons in race-track microtrons by means of an area preserving map with a fixed point at the origin, which represents the synchronous trajectory of a reference particle in the beam. We study the…
The stability of a complex system generally decreases with increasing system size and interconnectivity, a counterintuitive result of widespread importance across the physical, life, and social sciences. Despite recent interest in the…
The common understanding of protein evolution has been that neutral or slightly deleterious mutations are fixed by random drift, and evolutionary rate is determined primarily by the proportion of neutral mutations. However, recent studies…
We present a design framework to induce stable oscillations through mixed feedback control. We provide conditions on the feedback gain and on the balance between positive and negative feedback contributions to guarantee robust oscillations.…
*Automated circuit discovery* is a central tool in mechanistic interpretability for identifying the internal components of neural networks responsible for specific behaviors. While prior methods have made significant progress, they…
Understanding which system structure can sustain stable dynamics is a fundamental step in the design and analysis of large scale dynamical systems. Towards this goal, we investigate here the structural stability of systems with a random…
We introduce a novel framework for the stability analysis of discrete-time linear switching systems with switching sequences constrained by an automaton. The key element of the framework is the algebraic concept of multinorm, which…
This paper develops a unified analytical framework for determinant identities under finite-rank perturbations of square matrices that remains valid without invertibility assumptions. In contrast to classical inverse-based formulations, the…