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Different strains competing for a common pool of susceptible individuals is a key problem in mathematical epidemiology. To address this problem, we investigate a two-strain model within a Susceptible-Infected-Recovered (SIR) framework.…

Populations and Evolution · Quantitative Biology 2026-04-28 Enrique C. Gabrick , Ana Luiza de Moraes , Ervin K. Lenzi , Iberê L. Caldas

In this study, a new and natural way of constructing a stochastic Susceptible-Infected-Susceptible (SIS) model is proposed. This approach is natural in the sense that the disease transmission rate, $\beta$, is substituted with a generic,…

Probability · Mathematics 2025-11-07 Berk Tan Perçin

Understanding the interplay of different traits in a co-infection system with multiple strains has many applications in ecology and epidemiology. Because of high dimensionality and complex feedbacks between traits manifested in infection…

Dynamical Systems · Mathematics 2021-04-16 Thi Minh Thao Le , Erida Gjini , Sten Madec

Coinfection phenomena are common in nature, yet there is a lack of analytical approaches for coinfection systems with a high number of circulating and interacting strains. In this paper, we investigated a coinfection SIS framework applied…

Populations and Evolution · Quantitative Biology 2026-02-06 Sten Madec , Nicola Cinardi , Erida Gjini

This work examines the dynamics of solutions of a two-strain SIS epidemic model in patchy environments. The basic reproduction number $\mathcal{R}_0$ is introduced, and sufficient conditions are provided to guarantee the global stability of…

Analysis of PDEs · Mathematics 2023-09-12 Jonas T. Doumatè , Tahir B. Issa , Rachidi B. Salako

We consider a simple stochastic model for the spread of a disease caused by two virus strains in a closed homogeneously mixing population of size N. The spread of each strain in the absence of the other one is described by the stochastic…

Probability · Mathematics 2018-02-13 Fabio Lopes , Malwina Luczak

We introduce a two-strain model with asymmetric temporary immunity periods and partial cross-immunity. We derive explicit conditions for competitive exclusion and coexistence of the strains depending on the strain-specific basic…

Dynamical Systems · Mathematics 2023-06-28 Matthew D. Johnston , Bruce Pell , David A. Rubel

The crisis caused by the COVID-19 outbreak around the globe raised an increasing concern about the ongoing emergence of variants of SARS-CoV-2 that may evade the immune response provided by vaccines. New variants appear due to mutation, and…

Populations and Evolution · Quantitative Biology 2022-12-14 M. Ahumada , A. Ledesma-Araujo , Leonardo Gordillo , Juan F. Marín

Many infectious diseases are comprised of multiple strains with examples including Influenza, tuberculosis, and Dengue virus. The time evolution of such systems is linked to a complex landscape shaped by interactions between competing…

Populations and Evolution · Quantitative Biology 2023-11-21 Nir Gavish , Musa Rabiu

We introduce and investigate an SIS-type model for the spread of an infectious disease, where the infected population is structured with respect to the different strain of the virus/bacteria they are carrying. Our aim is to capture the…

Analysis of PDEs · Mathematics 2019-03-25 Àngel Calsina , József Z. Farkas

The paper deals with the spread of two competing viruses over a network of population nodes, accounting for pairwise interactions and higher-order interactions (HOI) within and between the population nodes. We study the competitive…

Systems and Control · Electrical Eng. & Systems 2023-09-26 Sebin Gracy , Brian D. O. Anderson , Mengbin Ye , Cesar A. Uribe

We present a stochastic model for two successive SIR (Susceptible, Infectious, Recovered) epidemics in the same network structured population. Individuals infected during the first epidemic might have (partial) immunity for the second one.…

Populations and Evolution · Quantitative Biology 2024-10-29 Frank Ball , Abid Ali Lashari , David Sirl , Pieter Trapman

In this paper, we further investigate the global dynamics of a stochastic differential equation SIS (Susceptible-Infected-Susceptible) epidemic model recently proposed in [A. Gray et al., SIAM. J. Appl. Math., 71 (2011), 876-902]. We…

Dynamical Systems · Mathematics 2016-08-24 Chuang Xu

In this paper, we focus on the influence of heterogeneity and stochasticity of the population on the dynamical structure of a basic susceptible-infected-susceptible (SIS) model. First we prove that, upon a suitable mathematical…

Dynamical Systems · Mathematics 2017-02-28 Andreas Widder , Christian Kuehn

A probabilistic approach to the epidemic evolution on realistic social-contact networks allows for characteristic differences among subjects, including the individual number and structure of social contacts, and the heterogeneity of the…

Social and Information Networks · Computer Science 2022-02-11 Jan B. Broekaert , Davide La Torre , Faizal Hafiz

We study a bi-virus susceptible-infected-susceptible (SIS) epidemic model in which individuals are either susceptible or infected with one of two virus strains, and consider mutation-driven transitions between strains. The general case of…

Populations and Evolution · Quantitative Biology 2025-10-03 Urmee Maitra , Ashish R. Hota , Vaibhav Srivastava

In this study we investigate a novel approach to stochastically perturb the disease transmission coefficient, which is a key parameter in susceptible-infected-susceptible (SIS) models. Motivated by the papers [2] and [5], we perturb the…

Probability · Mathematics 2021-05-18 Alberto Lanconelli , Berk Tan Perçin

In this paper we consider a competition system in which two diseases spread by contact. We characterize the system behavior, establishing that only some configurations are possible. In particular we discover that coexistence of the two…

Dynamical Systems · Mathematics 2014-04-06 Roberto Cavoretto , Simona Collino , Bianca Giardino , Ezio Venturino

Deterministic approximations to stochastic Susceptible-Infectious-Susceptible models typically predict a stable endemic steady-state when above threshold. This can be hard to relate to the underlying stochastic dynamics, which has no…

Populations and Evolution · Quantitative Biology 2022-08-12 Christopher E. Overton , Robert R. Wilkinson , Adedapo Loyinmi , Joel C. Miller , Kieran J. Sharkey

Competition is the main driver of population dynamics, which shapes the genetic composition of populations and the assembly of ecological communities. Neutral models assume that all the individuals are equivalent and that the dynamics is…

Populations and Evolution · Quantitative Biology 2018-04-11 Matan Danino , Nadav M. Shnerb
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