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Computational methods are the most effective tools we have besides scientific experiments to explore the properties of complex biological systems. Progress is slowing because digital silicon computers have reached their limits in terms of…

Quantum Physics · Physics 2020-04-03 Viv Kendon

Owing to the computational complexity of electronic structure algorithms running on classical digital computers, the range of molecular systems amenable to simulation remains tightly circumscribed even after many decades of work. Quantum…

Quantum Physics · Physics 2022-05-18 Alexis Ralli , Michael I. Williams , Peter V. Coveney

Quantum computational chemistry has emerged as an important application of quantum computing. Hybrid quantum-classical computing methods, such as variational quantum eigensolvers (VQE), have been designed as promising solutions to quantum…

Simulations of chemical dynamics are a powerful means for understanding chemistry. However, classical computers struggle to simulate many chemical processes, especially non-adiabatic ones, where the Born-Oppenheimer approximation breaks…

The quantum information science community has seen a surge in new algorithmic developments across scientific domains. These developments have demonstrated polynomial or better improvements in computational and space complexity,…

Quantum Physics · Physics 2022-05-03 Vincent R. Pascuzzi , Ning Bao , Ang Li

The rational design of molecules and materials is becoming more and more important. With the advent of powerful computer systems and sophisticated algorithms, quantum chemistry plays an important role in rational design. While traditional…

Chemical Physics · Physics 2014-05-20 Thomas Weymuth , Markus Reiher

The search for meaningful structure in biological data has relied on cutting-edge advances in computational technology and data science methods. However, challenges arise as we push the limits of scale and complexity in biological problems.…

We study from a theoretical viewpoint the fundamental problem of efficiently computing the stationary distribution of general classes of structured Markov processes. In strong contrast with previous work, we consider this fundamental…

Quantum Physics · Physics 2025-06-18 Vasileios Kalantzis , Mark S. Squillante , Shashanka Ubaru

Constraint satisfaction problems are a central pillar of modern computational complexity theory. This survey provides an introduction to the rapidly growing field of Quantum Hamiltonian Complexity, which includes the study of quantum…

Quantum Physics · Physics 2016-04-05 Sevag Gharibian , Yichen Huang , Zeph Landau , Seung Woo Shin

In the current era, quantum resources are extremely limited, and this makes difficult the usage of quantum machine learning (QML) models. Concerning the supervised tasks, a viable approach is the introduction of a quantum locality…

Emerging Technologies · Computer Science 2024-01-04 Enrico Zardini , Enrico Blanzieri , Davide Pastorello

It is known that quantum computers, if available, would allow an exponential decrease in the computational cost of quantum simulations. We extend this result to show that the computation of molecular properties (energy derivatives) could…

Quantum Physics · Physics 2011-03-23 Ivan Kassal , Alán Aspuru-Guzik

Quantum chemistry calculations such as the prediction of molecular properties and modeling of chemical reactions are a few of the critical areas where near-term quantum computers can showcase quantum advantage. We present a method to…

Quantum Physics · Physics 2022-04-06 Utkarsh Azad , Harjinder Singh

By leveraging quantum-mechanical properties like superposition, entanglement, and interference, quantum computing (QC) offers promising solutions for problems that classical computing has not been able to solve efficiently, such as drug…

Human-Computer Interaction · Computer Science 2025-02-14 Hyeok Kim , Mingyoung J. Jeng , Kaitlin N. Smith

In this paper we extend both standard fault tolerance theory and Kitaev's model for quantum computation, combining them so as to yield quantitative results that reveal the interplay between the two. Our analysis establishes a methodology…

Quantum Physics · Physics 2007-07-03 Gerald Gilbert , Michael Hamrick , Yaakov S. Weinstein

Recently, a series of different measures quantifying memory effects in the quantum dynamics of open systems has been proposed. Here, we derive a mathematical representation for the non-Markovianity measure based on the exchange of…

The success of product quantization (PQ) for fast nearest neighbor search depends on the exponentially reduced complexities of both storage and computation with respect to the codebook size. Recent efforts have been focused on employing…

Computer Vision and Pattern Recognition · Computer Science 2015-12-23 Jiangbo Yuan , Xiuwen Liu

Quantum computing has attracted a lot of attention in recent years. It is one of the promising candidates for the next-generation computing paradigms. Basically, there are two technical lines to realize quantum computing. One is composing…

Quantum Physics · Physics 2025-06-18 Nyau Fisn , Houren Fu

In this paper, we show how the restriction of the Quantum Geometric Tensor to manifolds of states that can be generated through local interactions provides a new tool to understand the consequences of locality in physics. After a review of…

Quantum Physics · Physics 2021-07-15 Davide Rattacaso , Patrizia Vitale , Alioscia Hamma

Classical simulation of real-space quantum dynamics is challenging due to the exponential scaling of computational cost with system dimensions. Quantum computer offers the potential to simulate quantum dynamics with polynomial complexity;…

Quantum Physics · Physics 2021-10-13 Chee-Kong Lee , Chang-Yu Hsieh , Shengyu Zhang , Liang Shi

Quantum computation of the energy of molecules and materials is one of the most promising applications of fault-tolerant quantum computers. Practical applications require development of quantum algorithms with reduced resource requirements.…

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