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Modelling the substitution of nucleotides along a phylogenetic tree is usually done by a hidden Markov process. This allows to define a distribution of characters at the leaves of the trees and one might be able to obtain polynomial…

Populations and Evolution · Quantitative Biology 2020-10-12 Marta Casanellas , Jesús Fernández-Sánchez , Marina Garrote-López

The exact maximum likelihood estimate (MLE) provides a test statistic for the unit root test that is more powerful \citep[p. 577]{Fuller96} than the usual least squares approach. In this paper a new derivation is given for the asymptotic…

Statistics Theory · Mathematics 2016-11-04 Ying Zhang , H. Yu , A. I. McLeod

Estimating species and gene trees from sequence data is challenging. Gene tree estimation is often hampered by low phylogenetic signal in alignments, leading to inaccurate trees. Species tree estimation is complicated by incomplete lineage…

Populations and Evolution · Quantitative Biology 2025-11-06 Ashu Gupta

The challenges posed by complex stochastic models used in computational ecology, biology and genetics have stimulated the development of approximate approaches to statistical inference. Here we focus on Synthetic Likelihood (SL), a…

Methodology · Statistics 2017-06-09 Matteo Fasiolo , Simon N. Wood , Florian Hartig , Mark V. Bravington

Using topological summaries of gene trees as a basis for species tree inference is a promising approach to obtain acceptable speed on genomic-scale datasets, and to avoid some undesirable modeling assumptions. Here we study the…

Populations and Evolution · Quantitative Biology 2017-04-17 Elizabeth S. Allman , James H. Degnan , John A. Rhodes

We study the ChorHendySnir2006 evolutionary model, which consists of a rooted phylogenetic tree with three leaves, subject to the Jukes--Cantor (JC69) molecular evolutionary model and molecular clock. We show that the likelihood function…

Populations and Evolution · Quantitative Biology 2026-01-23 Maria Emilíia Alonso , Ernesto Álvarez

We propose an algorithm named best-scored random forest for binary classification problems. The terminology "best-scored" means to select the one with the best empirical performance out of a certain number of purely random tree candidates…

Machine Learning · Statistics 2019-05-28 Hanyuan Hang , Xiaoyu Liu , Ingo Steinwart

Classifying sequential data as early and as accurately as possible is a challenging yet critical problem, especially when a sampling cost is high. One algorithm that achieves this goal is the sequential probability ratio test (SPRT), which…

Machine Learning · Computer Science 2021-02-09 Akinori F. Ebihara , Taiki Miyagawa , Kazuyuki Sakurai , Hitoshi Imaoka

The recursive and hierarchical structure of full rooted trees is applicable to represent statistical models in various areas, such as data compression, image processing, and machine learning. In most of these cases, the full rooted tree is…

Machine Learning · Statistics 2022-03-24 Yuta Nakahara , Shota Saito , Akira Kamatsuka , Toshiyasu Matsushima

Combining a set of phylogenetic trees into a single phylogenetic network that explains all of them is a fundamental challenge in evolutionary studies. Existing methods are computationally expensive and can either handle only small numbers…

Populations and Evolution · Quantitative Biology 2023-04-07 Giulia Bernardini , Leo van Iersel , Esther Julien , Leen Stougie

We address phylogenetic reconstruction when the data is generated from a mixture distribution. Such topics have gained considerable attention in the biological community with the clear evidence of heterogeneity of mutation rates. In our…

Populations and Evolution · Quantitative Biology 2007-05-23 Daniel Stefankovic , Eric Vigoda

Pedigree graphs, or family trees, are typically constructed by an expensive process of examining genealogical records to determine which pairs of individuals are parent and child. New methods to automate this process take as input genetic…

Data Structures and Algorithms · Computer Science 2011-10-19 Bonnie Kirkpatrick , Yakir Reshef , Hilary Finucane , Haitao Jiang , Binhai Zhu , Richard M. Karp

Determining the interaction partners among protein/domain families poses hard computational problems, in particular in the presence of paralogous proteins. Available approaches aim to identify interaction partners among protein/domain…

Populations and Evolution · Quantitative Biology 2015-01-14 Iman Hajirasouliha , Alexander Schönhuth , David Juan , Alfonso Valencia , S. Cenk Sahinalp

Compatibility of phylogenetic trees is the most important concept underlying widely-used methods for assessing the agreement of different phylogenetic trees with overlapping taxa and combining them into common supertrees to reveal the tree…

Discrete Mathematics · Computer Science 2011-11-09 Merce Llabres , Jairo Rocha , Francesc Rossello , Gabriel Valiente

Understanding the dynamics of genome rearrangements is a major issue of phylogenetics. Phylogenetics is the study of species evolution. A major goal of the field is to establish evolutionary relationships within groups of species, in order…

Data Structures and Algorithms · Computer Science 2014-10-22 Antoine Thomas

Staged trees are probabilistic graphical models capable of representing any class of non-symmetric independence via a coloring of its vertices. Several structural learning routines have been defined and implemented to learn staged trees…

Machine Learning · Statistics 2024-05-29 Jack Storror Carter , Manuele Leonelli , Eva Riccomagno , Gherardo Varando

Phylogenetics uses alignments of molecular sequence data to learn about evolutionary trees relating species. Along branches, sequence evolution is modelled using a continuous-time Markov process characterised by an instantaneous rate…

We find surprisingly simple formulas for the limiting probability that the rank of a randomly selected vertex in a randomly selected phylogenetic tree or generalized phylogenetic tree is a given integer.

Combinatorics · Mathematics 2023-06-22 Miklós Bóna

We study the fundamental question of how likely it is that two randomly chosen trees are isomorphic to each other for different models of random trees. We show that the probability decays exponentially for rooted labeled trees as well as…

Probability · Mathematics 2023-04-11 Christoffer Olsson

The k-nearest-neighbour procedure is a well-known deterministic method used in supervised classification. This paper proposes a reassessment of this approach as a statistical technique derived from a proper probabilistic model; in…

Computation · Statistics 2008-02-12 Lionel Cucala , Jean-Michel Marin , Christian Robert , Mike Titterington
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