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Molecular profiling data (e.g., gene expression) has been used for clinical risk prediction and biomarker discovery. However, it is necessary to integrate other prior knowledge like biological pathways or gene interaction networks to…

Genomics · Quantitative Biology 2016-09-22 Wenwen Min , Juan Liu , Shihua Zhang

The high cost and data scarcity in scientific exploration have motivated the use of large language models (LLMs) as knowledge-driven components in Bayesian optimization (BO). However, existing approaches typically embed LLMs directly into…

Regression by composition provides a flexible framework for constructing conditional distributions through sequential group actions. However, when multiple flows act on the same distribution, the model becomes non-identifiable, leading to…

Methodology · Statistics 2026-03-30 Safaa K. Kadhem

There has been an explosion of interest in using $l_1$-regularization in place of $l_0$-regularization for feature selection. We present theoretical results showing that while $l_1$-penalized linear regression never outperforms…

Statistics Theory · Mathematics 2015-10-22 Kory D. Johnson , Dongyu Lin , Lyle H. Ungar , Dean P. Foster , Robert A. Stine

The l1-regularized logistic regression (or sparse logistic regression) is a widely used method for simultaneous classification and feature selection. Although many recent efforts have been devoted to its efficient implementation, its…

Machine Learning · Computer Science 2013-07-22 Jie Wang , Jiayu Zhou , Jun Liu , Peter Wonka , Jieping Ye

Penalization schemes like Lasso or ridge regression are routinely used to regress a response of interest on a high-dimensional set of potential predictors. Despite being decisive, the question of the relative strength of penalization is…

Methodology · Statistics 2018-11-08 Britta Velten , Wolfgang Huber

Sparse logistic regression is for classification and feature selection simultaneously. Although many studies have been done to solve $\ell_1$-regularized logistic regression, there is no equivalently abundant work on solving sparse logistic…

Machine Learning · Computer Science 2023-10-13 Mengyuan Zhang , Kai Liu

We introduce a novel scheme for choosing the regularization parameter in high-dimensional linear regression with Lasso. This scheme, inspired by Lepski's method for bandwidth selection in non-parametric regression, is equipped with both…

Methodology · Statistics 2016-11-09 Michaël Chichignoud , Johannes Lederer , Martin Wainwright

Logistic regression is a widely used statistical model to describe the relationship between a binary response variable and predictor variables in data sets. It is often used in machine learning to identify important predictor variables.…

Optimization and Control · Mathematics 2021-12-30 Jérôme Darbon , Gabriel P. Langlois

We consider the problem of simultaneous variable selection and estimation of the corresponding regression coefficients in an ultra-high dimensional linear regression models, an extremely important problem in the recent era. The adaptive…

Methodology · Statistics 2023-09-22 Abhik Ghosh , Maria Jaenada , Leandro Pardo

The paper demonstrates the use of LASSO-based estimation in network models. Taking the Exponential Random Graph Model (ERGM) as a flexible and widely used model for network data analysis, the paper focuses on the question of how to specify…

Methodology · Statistics 2024-09-13 Sergio Buttazzo , Göran Kauermann

Bayesian optimization (BO) is a leading method for optimizing expensive black-box optimization and has been successfully applied across various scenarios. However, BO suffers from the curse of dimensionality, making it challenging to scale…

Machine Learning · Computer Science 2025-04-03 Vu Viet Hoang , Hung The Tran , Sunil Gupta , Vu Nguyen

We explore algorithms and limitations for sparse optimization problems such as sparse linear regression and robust linear regression. The goal of the sparse linear regression problem is to identify a small number of key features, while the…

Machine Learning · Computer Science 2022-06-30 Eric Price , Sandeep Silwal , Samson Zhou

Decision trees are widely-used classification and regression models because of their interpretability and good accuracy. Classical methods such as CART are based on greedy approaches but a growing attention has recently been devoted to…

Machine Learning · Computer Science 2021-12-16 Edoardo Amaldi , Antonio Consolo , Andrea Manno

The $\ell_0$-constrained empirical risk minimization ($\ell_0$-ERM) is a promising tool for high-dimensional statistical estimation. The existing analysis of $\ell_0$-ERM estimator is mostly on parameter estimation and support recovery…

Statistics Theory · Mathematics 2020-01-22 Xiao-Tong Yuan , Ping Li

The Least Absolute Shrinkage and Selection Operator (LASSO) has gained attention in a wide class of continuous parametric estimation problems with promising results. It has been a subject of research for more than a decade. Due to the…

Computation · Statistics 2015-04-13 Ashkan Panahi , Mats Viberg

Lasso and other regularization procedures are attractive methods for variable selection, subject to a proper choice of shrinkage parameter. Given a set of potential subsets produced by a regularization algorithm, a consistent model…

Methodology · Statistics 2014-02-26 Minh-Ngoc Tran

We study the problem of learning a sparse linear regression vector under additional conditions on the structure of its sparsity pattern. This problem is relevant in machine learning, statistics and signal processing. It is well known that a…

Machine Learning · Statistics 2015-03-17 Charles A. Micchelli , Jean M. Morales , Massimiliano Pontil

This paper provides a statistical analysis of high-dimensional batch Reinforcement Learning (RL) using sparse linear function approximation. When there is a large number of candidate features, our result sheds light on the fact that…

Machine Learning · Computer Science 2020-11-10 Botao Hao , Yaqi Duan , Tor Lattimore , Csaba Szepesvári , Mengdi Wang

We propose a practical method for $L_0$ norm regularization for neural networks: pruning the network during training by encouraging weights to become exactly zero. Such regularization is interesting since (1) it can greatly speed up…

Machine Learning · Statistics 2018-06-25 Christos Louizos , Max Welling , Diederik P. Kingma
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