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Survival analysis, or time-to-event analysis, is an important and widespread problem in healthcare research. Medical research has traditionally relied on Cox models for survival analysis, due to their simplicity and interpretability. Cox…

Machine Learning · Computer Science 2023-10-25 Mike Van Ness , Tomas Bosschieter , Natasha Din , Andrew Ambrosy , Alexander Sandhu , Madeleine Udell

Electronic health records (EHR) are characterized as non-stationary, heterogeneous, noisy, and sparse data; therefore, it is challenging to learn the regularities or patterns inherent within them. In particular, sparseness caused mostly by…

Machine Learning · Computer Science 2020-03-03 Eunji Jun , Ahmad Wisnu Mulyadi , Jaehun Choi , Heung-Il Suk

Online Surgical Phase Recognition (SPR) models can reach high frame-wise accuracy, yet their predictions often lack temporal stability, fragmenting workflow understanding and reducing the reliability of downstream assistance. We show that…

Computer Vision and Pattern Recognition · Computer Science 2026-05-19 Yang Liu , Ning Zhu , Jingjing Peng , Xiwu Chen , Alejandro Granados , Guotai Wang , Sebastien Ourselin

Increasing volume of Electronic Health Records (EHR) in recent years provides great opportunities for data scientists to collaborate on different aspects of healthcare research by applying advanced analytics to these EHR clinical data. A…

Machine Learning · Computer Science 2019-10-01 Najibesadat Sadati , Milad Zafar Nezhad , Ratna Babu Chinnam , Dongxiao Zhu

Predicting an individual's risk of experiencing a future clinical outcome is a statistical task with important consequences for both practicing clinicians and public health experts. Modern observational databases such as electronic health…

Increasing volume of Electronic Health Records (EHR) in recent years provides great opportunities for data scientists to collaborate on different aspects of healthcare research by applying advanced analytics to these EHR clinical data. A…

Machine Learning · Computer Science 2019-09-23 Najibesadat Sadati , Milad Zafar Nezhad , Ratna Babu Chinnam , Dongxiao Zhu

In healthcare, risk assessment of patient outcomes has been based on survival analysis for a long time, i.e. modeling time-to-event associations. However, conventional approaches rely on data from a single time-point, making them suboptimal…

Machine Learning · Computer Science 2026-02-20 Mine Öğretir , Miika Koskinen , Juha Sinisalo , Risto Renkonen , Harri Lähdesmäki

Electronic health records (EHR) consist of longitudinal clinical observations portrayed with sparsity, irregularity, and high-dimensionality, which become major obstacles in drawing reliable downstream clinical outcomes. Although there…

Machine Learning · Computer Science 2020-11-17 Ahmad Wisnu Mulyadi , Eunji Jun , Heung-Il Suk

Trustworthy survival prediction is essential for clinical decision making. Longitudinal electronic health records (EHRs) provide a uniquely powerful opportunity for the prediction. However, it is challenging to accurately model the…

Machine Learning · Computer Science 2025-08-04 Sihang Zeng , Lucas Jing Liu , Jun Wen , Meliha Yetisgen , Ruth Etzioni , Gang Luo

Intelligent medical diagnosis has shown remarkable progress based on the large-scale datasets with precise annotations. However, fewer labeled images are available due to significantly expensive cost for annotating data by experts. To fully…

Image and Video Processing · Electrical Eng. & Systems 2023-03-06 Wentao Lei , Lei Liu , Li Liu

The objective of this work is to develop an Electronic Medical Record (EMR) data processing tool that confers clinical context to Machine Learning (ML) algorithms for error handling, bias mitigation and interpretability. We present…

Most prediction models that are used in medical research fail to accurately predict health outcomes due to methodological limitations. Using routinely collected patient data, we explore the use of a Cox proportional hazard (PH) model within…

Methodology · Statistics 2019-07-19 John Mbotwa , Marc de Kamps , Paul D. Baxter , Mark S. Gilthorpe

Clinical decision support tools built on electronic health records often experience performance drift due to temporal population shifts, particularly when changes in the clinical environment initially affect only a subset of patients,…

Machine Learning · Computer Science 2025-12-16 Mengying Yan , Ziye Tian , Siqi Li , Nan Liu , Benjamin A. Goldstein , Molei Liu , Chuan Hong

The impact of machine learning models on healthcare will depend on the degree of trust that healthcare professionals place in the predictions made by these models. In this paper, we present a method to provide people with clinical expertise…

Machine Learning · Computer Science 2021-03-05 Aniruddh Raghu , John Guttag , Katherine Young , Eugene Pomerantsev , Adrian V. Dalca , Collin M. Stultz

Noninvasive reconstruction of cardiac electrical activity from surface electrocardiograms (ECG) involves solving an ill-posed inverse problem. Cardiac electrophysiological (EP) models have been used as important a priori knowledge to…

Image and Video Processing · Electrical Eng. & Systems 2019-05-14 Sandesh Ghimire , John L Sapp , Milan Horacek , Linwei Wang

Accurate early prediction of in-hospital mortality in intensive care units (ICUs) is essential for timely clinical intervention and efficient resource allocation. This study develops and evaluates machine learning models that integrate both…

Machine Learning · Computer Science 2025-10-22 Nursultan Mamatov , Philipp Kellmeyer

Predicting future clinical events from longitudinal electronic health records (EHRs) requires selecting plausible outcomes from a large and structured event space under sparse observations. While clinical coding systems provide hierarchical…

Machine Learning · Computer Science 2026-05-08 Zhan Qu , Michael Färber

Interval-censored data arise frequently in scientific studies, where the event of interest is known only to occur within a specific time interval. In such studies, functional covariates taking the form of continuous curves or spatial…

Methodology · Statistics 2026-05-18 Yangjianchen Xu , Peijun Sang

Recent research has shown the potential for neural networks to improve upon classical survival models such as the Cox model, which is widely used in clinical practice. Neural networks, however, typically rely on data that are centrally…

Machine Learning · Computer Science 2022-07-12 Dekai Zhang , Francesca Toni , Matthew Williams

Accurate prediction of clinical outcomes using Electronic Health Records (EHRs) is critical for early intervention, efficient resource allocation, and improved patient care. EHRs contain multimodal data, including both structured data and…

Machine Learning · Computer Science 2025-08-29 Rituparna Datta , Jiaming Cui , Zihan Guan , Vishal G. Reddy , Joshua C. Eby , Gregory Madden , Rupesh Silwal , Anil Vullikanti