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We present a method to differentiate organisms solely by their motion based on the generalized Langevin equation (GLE) and use it to distinguish two different swimming modes of strongly confined unicellular microalgae Chlamydomonas…

Biological Physics · Physics 2024-05-24 Anton Klimek , Debasmita Mondal , Stephan Block , Prerna Sharma , Roland R. Netz

We present a first-principles thermodynamic approach to provide an alternative to the Langevin equation by identifying the deterministic (no stochastic component) microforce F_{k,BP} acting on a nonequilibrium Brownian particle (BP) in its…

Statistical Mechanics · Physics 2020-08-26 P. D. Gujrati

We study the stochastic motion of an intruder in a dilute driven granular gas. All particles are coupled to a thermostat, representing the external energy source, which is the sum of random forces and a viscous drag. The dynamics of the…

Statistical Mechanics · Physics 2010-04-27 Alessandro Sarracino , Dario Villamaina , Giulio Costantini , Andrea Puglisi

Dynamical random walk of classical particle in thermodynamically equilibrium fluctuating medium, - Gaussian random potential field, - is considered in the framework of explicit stochastic representation of deterministic interactions. We…

Statistical Mechanics · Physics 2013-02-05 Yu. E. Kuzovlev

The Fractional Langevin Equation (FLE) describes a non-Markovian Generalized Brownian Motion with long time persistence (superdiffusion), or anti-persistence (subdiffusion) of both velocity-velocity correlations, and position increments. It…

Statistical Mechanics · Physics 2011-07-11 P. Siegle , I. Goychuk , P. Hanggi

Methods to extract information from the tracking of mobile objects/particles have broad interest in biological and physical sciences. Techniques based on simple criteria of proximity in time-consecutive snapshots are useful to identify the…

Data Analysis, Statistics and Probability · Physics 2015-03-13 M. Chertkov , L. Kroc , F. Krzakala , M. Vergassola , L. Zdeborová

This work proposes a method for the two-dimensional simulation of Brownian particles in a fluid with restrictions. The method is based on simple numerical rules between two matrices. One of the matrix represent the identification of all…

Statistical Mechanics · Physics 2012-04-24 Eric Plaza

The mean first passage time (MFPT) is a key metric for understanding transport, search, and escape processes in stochastic systems. While well characterized for passive Brownian particles, its behavior in active systems-such as active…

Soft Condensed Matter · Physics 2025-10-22 Sarafa A. Iyaniwura , Zhiwei Peng

This research presents a framework for describing the average velocity magnitude of an accelerated, self-propelled Brownian particle diffusing in a thermal fluid and confined by a harmonic external potential. The system is immersed in a…

Statistical Mechanics · Physics 2026-05-05 Pedro J. Colmenares

In this study we derive a single-particle equation of motion, from first-principles, starting out with a microscopic description of a tracer particle in a one-dimensional many-particle system with a general two-body interaction potential.…

Statistical Mechanics · Physics 2015-05-14 Ludvig Lizana , Tobias Ambjornsson , Alessandro Taloni , Eli Barkai , Michael A. Lomholt

The Wiener's path integral plays a central role in the studies of Brownian motion. Here we derive exact path-integral representations for the more general \emph{fractional} Brownian motion (fBm) and for its time derivative process -- the…

Statistical Mechanics · Physics 2022-12-28 Baruch Meerson , Olivier Bénichou , Gleb Oshanin

The analysis of local minima in time series data and random landscapes is essential across numerous scientific disciplines, offering critical insights into system dynamics. Recently, Kundu, Majumdar, and Schehr derived the exact…

Statistical Mechanics · Physics 2026-03-19 Maxim Dolgushev , Olivier Bénichou

We measured the overall motion of Brownian particles suspended in water by a self-mixing thin-slice solid-state laser with extreme optical sensitivity. From the demodulated signal of laser intensity fluctuations through self-mixing…

Heterogeneous diffusion processes are prevalent in various fields, including the motion of proteins in living cells, the migratory movement of birds and mammals, and finance. These processes are often characterized by time-varying dynamics,…

Statistical Mechanics · Physics 2025-03-11 Michał Balcerek , Adrian Pacheco-Pozo , Agnieszka Wyłomańska , Diego Krapf

Modern developments in microscopy and image processing are revolutionizing areas of physics, chemistry and biology as nanoscale objects can be tracked with unprecedented accuracy. The goal of single particle tracking is to determine the…

Statistical Mechanics · Physics 2015-06-04 Denis Boyer , David S. Dean , Carlos Mejía-Monasterio , Gleb Oshanin

The path-integral representation of Smoluchowski equation is exploited to explore the stochastic dynamics of a tagged Brownian particle within an interacting system where hydrodynamic effects are neglected. In particular, this formalism is…

Single Particle Tracking (SPT) can aid in understanding complex spatio-temporal processes. However, quantifying diffusivity and forces from individual live cell trajectories is complicated by inter- & intra-trajectory kinetic heterogeneity,…

Quantitative Methods · Quantitative Biology 2016-05-19 Christopher P. Calderon

We present a comparative study on two theoretical descriptions of microrheological experiments. Using a generalized Langevin equation (GLE), we analyze the origin of the power-law behavior of the main properties of a viscoelastic medium.…

Statistical Mechanics · Physics 2009-11-13 I. Santamaria-Holek

The movement of intracellular cargo transported by molecular motors is commonly marked by switches between directed motion and stationary pauses. The predominant measure for assessing movement is effective diffusivity, which predicts the…

Quantitative Methods · Quantitative Biology 2024-12-31 Keisha J. Cook , Nathan Rayens , Linh Do , Christine K. Payne , Scott A. McKinley

It was previously believed that diffusion of a tracer particle in a viscoelastic material should be of the fractional Brownian motion (fBm) type. This is due to the long-term memory in the response of such materials to mechanical…

Soft Condensed Matter · Physics 2024-06-19 Maayan Levin , Golan Bel , Yael Roichman