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Initiation and development of a malignant tumor is a complex phenomenon that has critical stages determining its long time behavior. This phenomenon is mathematically described by means of various models: from simple heuristic models to…

Populations and Evolution · Quantitative Biology 2020-03-23 Yuri Kozitsky , Krzysztof Pilorz

Tumor growth has long been a target of investigation within the context of mathematical and computer modelling. The objective of this study is to propose and analyze a two-dimensional probabilistic cellular automata model to describe…

Tissues and Organs · Quantitative Biology 2009-11-13 E. A. Reis , L. B. L. Santos , S. T. R. Pinho

Mounting evidence underscores the prevalent hierarchical organization of cancer tissues. At the foundation of this hierarchy reside cancer stem cells, a subset of cells endowed with the pivotal role of engendering the entire cancer tissue…

Applications · Statistics 2023-08-21 Shuli Chen , Yuman Wang , Da Zhou , Jie Hu

In this paper, we study a phase-space analysis of a mathematical model of tumor growth with an immune response. Mathematical analysis of the model equations with multipoint initial condition, regarding to dissipativity, boundedness of…

Tissues and Organs · Quantitative Biology 2018-01-17 Veli Shakhmurov

Based on an extended time-space symmetry, a cylindrical model of gravitational geometrical dynamics with two time-like extra-dimensions leads to a microscopic geodesic description of the curved space-time. Due to interaction of a Higgs-like…

General Physics · Physics 2015-10-15 Vo Van Thuan

In this paper, we conduct a thorough mathematical analysis of a tumor growth model with treatments. The model is a system describing the evolution of metastatic tumors and the number of cells present in a primary tumor. The former evolution…

Analysis of PDEs · Mathematics 2022-05-25 Slah Eddin Ben Abdeljalil , Atef Ben Essid , Saloua Mani Aouadi

In this paper, a single population model with memory effect and the heterogeneity of the environment, equipped with the Neumann boundary, is considered. The global existence of a spatial nonhomogeneous steady state is proved by the method…

Dynamical Systems · Mathematics 2020-05-25 Yujia Wang , Chuncheng Wang , Dejun Fan

This paper deals with the estimation of regions of attraction (RoAs) under parametric uncertainties for a cancer growth model with combined therapies. We propose a framework of probabilistic certification, based on the randomized methods,…

Systems and Control · Electrical Eng. & Systems 2020-04-30 Kaouther Moussa , Mirko Fiacchini , Mazen Alamir

Dealing with datasets of very high dimension is a major challenge in machine learning. In this paper, we consider the problem of feature selection in applications where the memory is not large enough to contain all features. In this…

Machine Learning · Statistics 2017-09-07 Antonio Sutera , Célia Châtel , Gilles Louppe , Louis Wehenkel , Pierre Geurts

The interfacial structure formed in thermoreversible associating polymer solutions is studied within the density functional approach based on Flory's arguments of tree-like configurations of cluster associations. The unique characteristics…

Condensed Matter · Physics 2007-05-23 Aleksander V. Ermoshkin , Igor Erukhimovich , Jeff Z. Y. Chen

We introduce a stochastic individual model for the spatial behavior of an animal population of dispersive and competitive species, considering various kinds of biological effects, such as heterogeneity of environmental conditions, mutual…

Probability · Mathematics 2016-07-05 Joaquin Fontbona , Sylvie Méléard

We present a phase-space analysis of a mathematical model of tumor growth with an immune responses. We consider mathematical analysis of the model equations with multipoint initial condition regarding to dissipativity, boundedness of…

Dynamical Systems · Mathematics 2019-02-28 Veli Shakhmurov , Rishad Shahmurov

Organisms modulate their fitness in heterogeneous environments by dispersing. Prior work shows that there is selection against "unconditional" dispersal in spatially heterogeneous environments. "Unconditional" means individuals disperse at…

Populations and Evolution · Quantitative Biology 2011-09-28 Sebastian J. Schreiber , Chi-Kwong Li

We consider a weakly coupled singularly perturbed variational elliptic system in a bounded smooth domain with Dirichlet boundary conditions. We show that, in the competitive regime, the number of fully nontrivial solutions with nonnegative…

Analysis of PDEs · Mathematics 2024-01-01 Mónica Clapp , Alberto Saldaña , Andrzej Szulkin

We investigate the evolution of quiescence within the framework of Adaptive Dynamics for an SIQS (Susceptible - Infected - Quiescent) model with constant environment. In the first part of the paper, the competition of two strains which have…

Populations and Evolution · Quantitative Biology 2025-07-14 Leonard Braun , Noah Risse , Aurélien Tellier , Johannes Müller

The problem of pattern selection arises when the evolution equations have many solutions, whereas observed patterns constitute a much more restricted set. An approach is advanced for treating the problem of pattern selection by defining the…

Condensed Matter · Physics 2009-11-07 V. I. Yukalov

We consider the energetic description of a visco-plastic evolution and derive an existence result. The energies are convex, but not necessarily quadratic. Our model is a strain gradient model in which the curl of the plastic strain…

Analysis of PDEs · Mathematics 2017-04-19 Matthias Röger , Ben Schweizer

Mass is commonly regarded as an intrinsic property of matter, but modern physics reveals particle masses to have complex origins, such as the Higgs mechanism in high-energy physics. In crystal lattices such as graphene, relativistic Dirac…

Mesoscale and Nanoscale Physics · Physics 2024-04-16 Letian Yu , Haoran Xue , Ruixiang Guo , Eng Aik Chan , Yun Yong Terh , Cesare Soci , Baile Zhang , Y. D. Chong

Models of tissue growth are now well established, in particular in relation to their applications to cancer. They describe the dynamics of cells subject to motion resulting from a pressure gradient generated by the death and birth of cells,…

Analysis of PDEs · Mathematics 2018-09-07 Piotr Gwiazda , Benoît Perthame , Agnieszka Świerczewska-Gwiazda

Random growth models are fundamental objects in modern probability theory, have given rise to new mathematics, and have numerous applications, including tumor growth and fluid flow in porous media. In this article, we introduce some of the…

Probability · Mathematics 2018-04-17 Michael Damron
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