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Recently, denoising diffusion models have demonstrated remarkable performance among generative models in various domains. However, in the speech domain, the application of diffusion models for synthesizing time-varying audio faces…

Audio and Speech Processing · Electrical Eng. & Systems 2023-06-13 Ji-Sang Hwang , Sang-Hoon Lee , Seong-Whan Lee

Gene transcription is a stochastic process that involves thousands of reactions. The first set of these reactions, which happen near a gene promoter, are considered to be the most important in the context of stochastic noise. The most…

Molecular Networks · Quantitative Biology 2022-02-01 Jaroslav Albert

Charge diffusion through desoxyribonucleic acid (DNA) is a physico-chemical phenomenon that on the one hand is being explored for technological purposes, on the other hand is applied by nature for various informational processes in life.…

Biological Physics · Physics 2024-07-22 Mirko Rossini , Ole Ammerpohl , Reiner Siebert , Joachim Ankerhold

In this paper, we present a causal speech signal improvement system that is designed to handle different types of distortions. The method is based on a generative diffusion model which has been shown to work well in scenarios with missing…

Audio and Speech Processing · Electrical Eng. & Systems 2023-03-16 Julius Richter , Simon Welker , Jean-Marie Lemercier , Bunlong Lay , Tal Peer , Timo Gerkmann

Diffusion models are a new class of generative models that have shown outstanding performance in image generation literature. As a consequence, studies have attempted to apply diffusion models to other tasks, such as speech enhancement. A…

Audio and Speech Processing · Electrical Eng. & Systems 2024-10-10 Philippe Gonzalez , Zheng-Hua Tan , Jan Østergaard , Jesper Jensen , Tommy Sonne Alstrøm , Tobias May

Extrinsic noise-induced transitions to bimodal dynamics have been largely investigated in a variety of chemical, physical, and biological systems. In the standard approach in physical and chemical systems, the key properties that make these…

Biological Physics · Physics 2020-11-10 Gerardo Aquino , Andrea Rocco

Diffusion models are typically trained using score matching, a learning objective agnostic to the underlying noising process that guides the model. This paper argues that Markov noising processes enjoy an advantage over alternatives, as the…

Machine Learning · Statistics 2025-05-27 Zheyang Shen , Huihui Wang , Marina Riabiz , Chris J. Oates

Denoising Diffusion Probabilistic Models have shown extraordinary ability on various generative tasks. However, their slow inference speed renders them impractical in speech synthesis. This paper proposes a linear diffusion model (LinDiff)…

Sound · Computer Science 2023-06-13 Haogeng Liu , Tao Wang , Jie Cao , Ran He , Jianhua Tao

In this paper, a new method to efficiently simulate diffusion controlled second order chemical reactions is derived and applied to site-specific DNA-binding proteins. The protein enters a spherical cell and propagates via two competing…

Biological Physics · Physics 2009-11-11 Holger Merlitz , Konstantin V. Klenin , Chen-Xu Wu , Jörg Langowski

Noise is one of the primary sources of interference in seismic exploration. Many authors have proposed various methods to remove noise from seismic data; however, in the face of strong noise conditions, satisfactory results are often not…

Geophysics · Physics 2024-04-04 Junheng Peng , Yong Li , Yingtian Liu , Zhangquan Liao

The goal of speech enhancement (SE) is to eliminate the background interference from the noisy speech signal. Generative models such as diffusion models (DM) have been applied to the task of SE because of better generalization in unseen…

Sound · Computer Science 2023-09-06 Wen Wang , Dongchao Yang , Qichen Ye , Bowen Cao , Yuexian Zou

We propose a simple and novel method for generating 3D human motion from complex natural language sentences, which describe different velocity, direction and composition of all kinds of actions. Different from existing methods that use…

Computer Vision and Pattern Recognition · Computer Science 2023-04-17 Zhiyuan Ren , Zhihong Pan , Xin Zhou , Le Kang

Recent advances in latent diffusion models have demonstrated state-of-the-art performance in high-dimensional time-series data synthesis while providing flexible control through conditioning and guidance. However, existing methodologies…

Machine Learning · Computer Science 2025-11-11 Matteo Pettenó , Alessandro Ilic Mezza , Alberto Bernardini

Diffusion models have achieved state-of-the-art synthesis quality on both visual and audio tasks, and recent works further adapt them to textual data by diffusing on the embedding space. In this paper, we conduct systematic studies of the…

Computation and Language · Computer Science 2024-04-23 Zhujin Gao , Junliang Guo , Xu Tan , Yongxin Zhu , Fang Zhang , Jiang Bian , Linli Xu

Gene products (RNAs, proteins) often occur at low molecular counts inside individual cells, and hence are subject to considerable random fluctuations (noise) in copy number over time. Not surprisingly, cells encode diverse regulatory…

Molecular Networks · Quantitative Biology 2015-10-01 Thierry Platini , Mohammad Soltani , Abhyudai Singh

Previous theoretical studies have shown that measuring the transverse current across DNA strands while they translocate through a nanopore or channel may provide a statistically distinguishable signature of the DNA bases, and may thus allow…

Soft Condensed Matter · Physics 2009-11-21 Matt Krems , Michael Zwolak , Yuriy V. Pershin , Massimiliano Di Ventra

When an individual's DNA is sequenced, sensitive medical information becomes available to the sequencing laboratory. A recently proposed way to hide an individual's genetic information is to mix in DNA samples of other individuals. We…

Information Theory · Computer Science 2024-11-05 Kayvon Mazooji , Roy Dong , Ilan Shomorony

In this work, we propose DiffWave, a versatile diffusion probabilistic model for conditional and unconditional waveform generation. The model is non-autoregressive, and converts the white noise signal into structured waveform through a…

Audio and Speech Processing · Electrical Eng. & Systems 2021-04-01 Zhifeng Kong , Wei Ping , Jiaji Huang , Kexin Zhao , Bryan Catanzaro

Diffusion probabilistic models are traditionally used to generate colors at fixed pixel positions in 2D images. Building on this, we extend diffusion models to point cloud semantic segmentation, where point positions also remain fixed, and…

Computer Vision and Pattern Recognition · Computer Science 2025-03-12 Yong He , Hongshan Yu , Mingtao Feng , Tongjia Chen , Zechuan Li , Anwaar Ulhaq , Saeed Anwar , Ajmal Saeed Mian

We consider a stochastic model of transcription factor (TF)-regulated gene expression. The model describes two genes: Gene A and Gene B which synthesize the TFs and the target gene proteins respectively. We show through analytic…

Quantitative Methods · Quantitative Biology 2009-11-13 Rajesh Karmakar , Indrani Bose
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