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Spatial confounding is how is called the confounding between fixed and spatial random effects. It has been widely studied and it gained attention in the past years in the spatial statistics literature, as it may generate unexpected results…

Spatial confounding is a fundamental issue in spatial regression models which arises because spatial random effects, included to approximate unmeasured spatial variation, are typically not independent of covariates in the model. This can…

Methodology · Statistics 2025-07-15 Emiko Dupont , Isa Marques , Thomas Kneib

The concept of spatial confounding is closely connected to spatial regression, although no general definition has been established. A generally accepted idea of spatial confounding in spatial regression models is the change in fixed effects…

Methodology · Statistics 2022-12-27 A. Urdangarin , T. Goicoa , M. D. Ugarte

Spatial confounding is a persistent challenge in spatial statistics, influencing the validity of statistical inference in models that analyze spatially-structured data. The concept has been interpreted in various ways but is broadly defined…

In the last two decades, considerable research has been devoted to a phenomenon known as spatial confounding. Spatial confounding is thought to occur when there is multicollinearity between a covariate and the random effect in a spatial…

Methodology · Statistics 2024-06-25 Kori Khan , Candace Berrett

Spatial models are used in a variety research areas, such as environmental sciences, epidemiology, or physics. A common phenomenon in many spatial regression models is spatial confounding. This phenomenon takes place when spatially indexed…

Methodology · Statistics 2021-06-08 Isa Marques , Thomas Kneib , Nadja Klein

A key challenge in environmental health research is unmeasured spatial confounding, driven by unobserved spatially structured variables that influence both treatment and outcome. A common approach is to fit a spatial regression that models…

Methodology · Statistics 2025-12-23 Sophie M. Woodward , Francesca Dominici , Jose R. Zubizarreta

Unmeasured spatial confounding complicates exposure effect estimation in environmental health studies. This problem is exacerbated in studies with multiple health outcomes and environmental exposure variables, as the source and magnitude of…

Studies in environmental and epidemiological sciences are often spatially varying and observational in nature with the aim of establishing cause and effect relationships. One of the major challenges with such studies is the presence of…

Methodology · Statistics 2023-05-16 Sayli Pokal , Yawen Guan , Honglang Wang , Yuzhen Zhou

Estimating effects of spatially structured exposures is complicated by unmeasured spatial confounders, which undermine identifiability in spatial linear regression models unless structural assumptions are imposed. We develop a general…

Methodology · Statistics 2025-12-30 Anik Burman , Elizabeth L. Ogburn , Abhirup Datta

This paper proposes a new approach to address the problem of unmeasured confounding in spatial designs. Spatial confounding occurs when some confounding variables are unobserved and not included in the model, leading to distorted…

Methodology · Statistics 2025-03-05 Carlo Zaccardi , Pasquale Valentini , Luigi Ippoliti , Alexandra M. Schmidt

We investigate spatial confounding in the presence of multivariate disease dependence. In the "analysis model perspective" of spatial confounding, adding a spatially dependent random effect can lead to significant variance inflation of the…

Methodology · Statistics 2026-02-13 Kyle Lin Wu , Sudipto Banerjee

1 - Spatial confounding is a phenomenon that has been studied extensively in recent years in the statistical literature to describe and mitigate apparent inconsistencies between the results obtained by regression models with and without…

Assessing associations between a response of interest and a set of covariates in spatial areal models is the leitmotiv of ecological regression. However, the presence of spatially correlated random effects can mask or even bias estimates of…

Methodology · Statistics 2021-06-02 A. Adin , T. Goicoa , J. S. Hodges , P. Schnell , M. D. Ugarte

Residuals in regression models are often spatially correlated. Prominent examples include studies in environmental epidemiology to understand the chronic health effects of pollutants. I consider the effects of residual spatial structure on…

Methodology · Statistics 2010-11-05 Christopher J. Paciorek

This paper investigates the problem of adjusting for spatial effects in genomic prediction. Despite being seldomly considered in genomic prediction, spatial effects often affect phenotypic measurements of plants. We consider a Gaussian…

Applications · Statistics 2020-06-09 Xiaojun Mao , Somak Dutta , Raymond K. W. Wong , Dan Nettleton

The issue of spatial confounding between the spatial random effect and the fixed effects in regression analyses has been identified as a concern in the statistical literature. Multiple authors have offered perspectives and potential…

Methodology · Statistics 2023-01-18 Kori Khan , Catherine A. Calder

This manuscript unites causal inference and spatial statistics, presenting novel insights for causal inference in spatial data analysis, and drawing from tools in spatial statistics to estimate causal effects. We introduce spatial causal…

Methodology · Statistics 2026-02-17 Georgia Papadogeorgou , Srijata Samanta

The estimation of regression parameters in spatially referenced data plays a crucial role across various scientific domains. A common approach involves employing an additive regression model to capture the relationship between observations…

Statistics Theory · Mathematics 2024-03-29 David Bolin , Jonas Wallin

Spatial confounding poses a significant challenge in scientific studies involving spatial data, where unobserved spatial variables can influence both treatment and outcome, possibly leading to spurious associations. To address this problem,…

Machine Learning · Computer Science 2024-12-04 Mauricio Tec , Ana Trisovic , Michelle Audirac , Sophie Woodward , Jie Kate Hu , Naeem Khoshnevis , Francesca Dominici
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