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Chimeric antigen receptor T-cell (CAR-T) therapy represents a paradigm shift in cancer treatment, yet development timelines of 8-12 years and clinical attrition rates exceeding 40-60% highlight critical inefficiencies in target selection,…

Quantitative Methods · Quantitative Biology 2025-11-13 Yi Ni , Liwei Zhu , Shuai Li

This study proposes a novel artificial protozoa optimizer (APO) that is inspired by protozoa in nature. The APO mimics the survival mechanisms of protozoa by simulating their foraging, dormancy, and reproductive behaviors. The APO was…

Neural and Evolutionary Computing · Computer Science 2025-05-07 Xiaopeng Wang , Vaclav Snasel , Seyedali Mirjalili , Jeng-Shyang Pan , Lingping Kong , Hisham A. Shehadeh

An analytical model of Human-Robot (H-R) coordination is presented for a Human-Robot system executing a collaborative task in which a high level of synchronization among the agents is desired. The influencing parameters and decision…

Robotics · Computer Science 2017-09-25 Roy Someshwar , Yoav Kerner

We study online task allocation for multi-robot, multi-queue systems with asymmetric stochastic arrivals and switching delays. We formulate the problem in discrete time: each location can host at most one robot per slot, servicing a task…

Systems and Control · Electrical Eng. & Systems 2026-04-07 Mohammad Merati , H. M. Sabbir Ahmad , Wenchao Li , David Castañón

Optical wireless communication offers unprecedented communication speeds that can support the massive use of the Internet on a daily basis. In indoor environments, optical wireless networks are usually multi-user multiple-input…

Signal Processing · Electrical Eng. & Systems 2021-11-30 Ahmad Adnan Qidan , Taisir El-Gorashi1 , Jaafar M. H. Elmirghani

Having completed its commissioning phase, the Advanced Rayleigh guided Ground-layer adaptive Optics System (ARGOS) facility is coming online for scientific observations at the Large Binocular Telescope (LBT). With six Rayleigh laser guide…

Robotic automation has transformed scientific workflows in domains such as chemistry and materials science, yet free-space optics, which is a high precision domain, remains largely manual. Optical systems impose strict spatial and angular…

Bayesian optimization (BO) is a class of global optimization algorithms, suitable for minimizing an expensive objective function in as few function evaluations as possible. While BO budgets are typically given in iterations, this implicitly…

Machine Learning · Computer Science 2020-03-25 Eric Hans Lee , Valerio Perrone , Cedric Archambeau , Matthias Seeger

We propose a framework for online meta-optimization of parameters that govern optimization, called Amortized Proximal Optimization (APO). We first interpret various existing neural network optimizers as approximate stochastic proximal point…

Machine Learning · Computer Science 2022-03-02 Juhan Bae , Paul Vicol , Jeff Z. HaoChen , Roger Grosse

Efficient surgery room scheduling is essential for hospital efficiency, patient satisfaction, and resource utilization. This study addresses this challenge by introducing a novel concept of Random-Key Optimizer (RKO), rigorously tested on…

Neural and Evolutionary Computing · Computer Science 2025-01-27 Bruno Salezze Vieira , Eduardo Machado Silva , Antonio Augusto Chaves

Traditional aggregate sorting methods, whether manual or mechanical, often suffer from low precision, limited flexibility, and poor adaptability to diverse material properties such as size, shape, and lithology. To address these…

Robotics · Computer Science 2025-09-03 Md. Taherul Islam Shawon , Yuan Li , Yincai Cai , Junjie Niu , Ting Peng

EAGLE is the multi-object, spatially-resolved, near-IR spectrograph instrument concept for the E-ELT, relying on a distributed Adaptive Optics, so-called Multi Object Adaptive Optics. This paper presents the results of a phase A study.…

Agentic AI enables LLM to dynamically reason, plan, and interact with tools to solve complex tasks. However, agentic workflows often require many iterative reasoning steps and tool invocations, leading to significant operational expense,…

Artificial Intelligence · Computer Science 2026-02-03 Sami Abuzakuk , Anne-Marie Kermarrec , Rishi Sharma , Rasmus Moorits Veski , Martijn de Vos

The availability and performance of laser-based adaptive optics (AO) systems are strongly dependent on the power and quality of the laser beam before being projected to the sky. Frequent and time-consuming alignment procedures are usually…

Instrumentation and Methods for Astrophysics · Physics 2014-05-23 Clémentine Béchet , Andrés Guesalaga , Benoit Neichel , Vincent Fesquet , Héctor González-Núñez , Sebastián Zúñiga , Pedro Escarate , Dani Guzman

To construct a robot that can walk as efficiently and steadily as humans or other legged animals, we develop an enhanced elitist-mutated ant colony optimization~(EACO) algorithm with genetic and crossover operators in real-time applications…

Neural and Evolutionary Computing · Computer Science 2020-10-12 Jingan Yang , Yang Peng

The automation system for Course of Action (CoA) planning is an essential element in future warfare. As maneuver speeds increase, surveillance ranges extend, and weapon ranges grow, the operational area expands, making traditional…

Artificial Intelligence · Computer Science 2026-04-24 Ji-il Park , Inwook Shim , Chong Hui Kim

Automotive radar has increasingly attracted attention due to growing interest in autonomous driving technologies. Acquiring situational awareness using multimodal data collected at high sampling rates by various sensing devices including…

Computer Vision and Pattern Recognition · Computer Science 2023-02-22 Madhumitha Sakthi , Ahmed Tewfik , Marius Arvinte , Haris Vikalo

Collaborative autonomous driving with multiple vehicles usually requires the data fusion from multiple modalities. To ensure effective fusion, the data from each individual modality shall maintain a reasonably high quality. However, in…

Artificial Intelligence · Computer Science 2024-08-02 Zhe Huang , Shuo Wang , Yongcai Wang , Wanting Li , Deying Li , Lei Wang

Astronomical adaptive optics systems are used to increase effective telescope resolution. However, they cannot be used to observe the whole sky since one or more natural guide stars of sufficient brightness must be found within the…

Instrumentation and Methods for Astrophysics · Physics 2018-04-11 Alastair Basden , Anthony M Brown , Paula Chadwick , Paul Clark , Richard Massey

The Adaptive Optics (AO) performance significantly depends on the available Natural Guide Stars (NGSs) and a wide range of atmospheric conditions (seeing, Cn2, windspeed,...). In order to be able to easily predict the AO performance, we…