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This paper introduces a variational formulation of natural selection, paying special attention to the nature of "things" and the way that different "kinds" of "things" are individuated from - and influence - each other. We use the Bayesian…

Populations and Evolution · Quantitative Biology 2023-07-05 Karl Friston , Daniel Ari Friedman , Axel Constant , V. Bleu Knight , Thomas Parr , John O. Campbell

The protein folding problem must ultimately be solved on all length scales from the atomic up through a hierarchy of complicated structures. By analyzing the stability of the folding process using physics and mathematics, this paper shows…

Biological Physics · Physics 2015-05-28 Walter Simmons , Joel L. Weiner

Rapid advances in genetics, genomics, and imaging have given insight into the molecular and cellular basis of behaviour in a variety of model organisms with unprecedented detail and scope. It is increasingly routine to isolate behavioural…

Quantitative Methods · Quantitative Biology 2013-01-08 André E. X. Brown , William R. Schafer

Wavefront shaping is a technique to study and control light transport inside scattering media. Wavefront shaping is considered to be applicable to any complex material, yet in most previous studies, the only sample geometries that are…

Understanding how cells respond to external stimuli is a central challenge in biomedical research and drug development. Current computational frameworks for modelling cellular responses remain restricted to two-dimensional representations,…

Computer Vision and Pattern Recognition · Computer Science 2025-10-27 Reed Naidoo , Matt De Vries , Olga Fourkioti , Vicky Bousgouni , Mar Arias-Garcia , Maria Portillo-Malumbres , Chris Bakal

Shape is an important physical property of natural and manmade 3D objects that characterizes their external appearances. Understanding differences between shapes and modeling the variability within and across shape classes, hereinafter…

Graphics · Computer Science 2018-12-27 Hamid Laga

Recent advances in human mobility research have revealed consistent pairwise characteristics in movement behavior, yet existing mobility models often overlook the spatial and topological structure of mobility networks. By analyzing millions…

Physics and Society · Physics 2025-05-22 Lu Zhong , Lei Dong , Qi Wang , Chaoming Song , Jianxi Gao

We often wish to classify objects by their shapes. Indeed, the study of shapes is an important part of many scientific fields such as evolutionary biology, structural biology, image processing, and archaeology. The most widely-used method…

Undulatory locomotion is a means of self-propulsion that relies on the generation and propagation of waves along a body. As a mode of locomotion it is primitive and relatively simple, yet can be remarkably robust. No wonder then, that it is…

Biological Physics · Physics 2009-08-20 Netta Cohen , Jordan H. Boyle

This study systematically investigates the dynamics of the bacterial transition from free-swimming to surface adhesion, a process characterized by both height $h$ and inclination angle $\Psi$. The surface entrapment process is divided into…

Soft Condensed Matter · Physics 2025-06-25 Baopi Liu , Bowen Jin , Ning An

A series of simulations aimed at elucidating the self-assembly dynamics of spherical virus capsids is described. This little-understood phenomenon is a fascinating example of the complex processes that occur in the simplest of organisms.…

Soft Condensed Matter · Physics 2015-05-19 D. C. Rapaport

T cells use sophisticated shape dynamics (morphodynamics) to migrate towards and neutralise infected and cancerous cells. However, there is limited quantitative understanding of the migration process in 3D extracellular matrices (ECMs) and…

Biological Physics · Physics 2022-04-11 Henry Cavanagh , Daryan Kempe , Jessica K. Mazalo , Maté Biro , Robert G. Endres

A formalism is derived to analyze the scattering of a conducting structure based on the characteristic modes of another structure whose surface is a superset of the first structure. This enables the analysis and comparison of different…

Signal Processing · Electrical Eng. & Systems 2025-12-10 Leonardo Mörlein , Dirk Manteuffel

We study the shape dynamics of a two-component fluid membrane, using a dynamical triangulation monte carlo simulation and a Langevin description. Phase separation induces morphology changes depending on the lateral mobility of the lipids.…

Soft Condensed Matter · Physics 2009-10-30 P. B. Sunil Kumar , Madan Rao

This paper introduces and demonstrates a computational pipeline for the statistical analysis of shape graph datasets, namely geometric networks embedded in 2D or 3D spaces. Unlike traditional abstract graphs, our purpose is not only to…

Machine Learning · Computer Science 2026-02-19 Murad Hossen , Demetrio Labate , Nicolas Charon

Functional properties of neurons are strongly coupled with their morphology. Changes in neuronal activity alter morphological characteristics of dendritic spines. First step towards understanding the structure-function relationship is to…

Computer Vision and Pattern Recognition · Computer Science 2016-07-20 Muhammad Usman Ghani , Ertunc Erdil , Sumeyra Demir Kanik , Ali Ozgur Argunsah , Anna Felicity Hobbiss , Inbal Israely , Devrim Unay , Tolga Tasdizen , Mujdat Cetin

Magnetic stimulation is a standard tool in brain research and many fields of neurology, as well as psychiatry. From a physical perspective, one key aspect of this method is the inefficiency of available setups. Whereas the spatial field…

Medical Physics · Physics 2011-06-20 Stefan M. Goetz , Nam C. Truong , Manuel G. Gerhofer , Thomas Weyh , Hans-Georg Herzog

One of the essential tasks in connectomics is the morphology analysis of neurons and organelles like mitochondria to shed light on their biological properties. However, these biological objects often have tangled parts or complex branching…

Computer Vision and Pattern Recognition · Computer Science 2020-04-22 Abhimanyu Talwar , Zudi Lin , Donglai Wei , Yuesong Wu , Bowen Zheng , Jinglin Zhao , Won-Dong Jang , Xueying Wang , Jeff W. Lichtman , Hanspeter Pfister

The shape evolution of two-dimensional islands through periphery diffusion biased by an electromigration force is studied numerically using a continuum approach. We show that the introduction of crystal anisotropy in the mobility of edge…

Materials Science · Physics 2009-11-10 Philipp Kuhn , Joachim Krug , Frank Hausser , Axel Voigt

In biology, cells undergo deformations under the action of flow caused by the fluid surrounding them. These flows lead to shape changes and instabilities that have been explored in detail for single component vesicles. However, cell…

Fluid Dynamics · Physics 2025-10-15 Anirudh Venkatesh , Vivek Narsimhan
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