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Visual query systems (VQSs) empower users to interactively search for line charts with desired visual patterns, typically specified using intuitive sketch-based interfaces. Despite decades of past work on VQSs, these efforts have not…

Computational chemistry allows researchers to experiment in sillico: by running a computer simulations of a biological or chemical processes of interest. Molecular dynamics with molecular mechanics model of interactions simulates N-body…

Distributed, Parallel, and Cluster Computing · Computer Science 2014-03-03 Jana Pazúriková

We present a novel task: text-to-3D sketch animation, which aims to bring freeform sketches to life in dynamic 3D space. Unlike prior works focused on photorealistic content generation, we target sparse, stylized, and view-consistent 3D…

Graphics · Computer Science 2025-10-30 Hao Chen , Jiaqi Wang , Yonggang Qi , Ke Li , Kaiyue Pang , Yi-Zhe Song

Advances in Generative AI tools have allowed designers to manipulate existing 3D models using text or image-based prompts, enabling creators to explore different design goals. Photochromic color-changing systems, on the other hand, allow…

Human-Computer Interaction · Computer Science 2024-04-29 Yunyi Zhu , Faraz Faruqi , Stefanie Mueller

Biomolecular interactions underpin almost all biological processes, and their rational design is central to programming new biological functions. Generative AI models have emerged as powerful tools for molecular design, yet most remain…

The freeform architectural modeling process often involves two important stages: concept design and digital modeling. In the first stage, architects usually sketch the overall 3D shape and the panel layout on a physical or digital paper…

Graphics · Computer Science 2022-04-27 Zhi Deng , Yang Liu , Hao Pan , Wassim Jabi , Juyong Zhang , Bailin Deng

Creating and editing the shape and color of 3D objects require tremendous human effort and expertise. Compared to direct manipulation in 3D interfaces, 2D interactions such as sketches and scribbles are usually much more natural and…

Computer Vision and Pattern Recognition · Computer Science 2022-07-26 Zezhou Cheng , Menglei Chai , Jian Ren , Hsin-Ying Lee , Kyle Olszewski , Zeng Huang , Subhransu Maji , Sergey Tulyakov

Sketch-based image editing aims to synthesize and modify photos based on the structural information provided by the human-drawn sketches. Since sketches are difficult to collect, previous methods mainly use edge maps instead of sketches to…

Computer Vision and Pattern Recognition · Computer Science 2020-01-10 Shuai Yang , Zhangyang Wang , Jiaying Liu , Zongming Guo

Innovation in synthetic biology often still depends on large-scale experimental trial-and-error, domain expertise, and ingenuity. The application of rational design engineering methods promise to make this more efficient, faster, cheaper…

Molecular Networks · Quantitative Biology 2021-08-18 Robyn P. Araujo , Sean T. Vittadello , Michael P. H. Stumpf

Traditional robotic manipulator design methods require extensive, time-consuming, and manual trial and error to produce a viable design. During this process, engineers often spend their time redesigning or reshaping components as they…

Robotics · Computer Science 2022-04-15 Lara Zlokapa , Yiyue Luo , Jie Xu , Michael Foshey , Kui Wu , Pulkit Agrawal , Wojciech Matusik

Sketching is an important means of communication in software engineering practice. Yet, there is little research investigating the use of sketches. We want to contribute a better understanding of sketching, in particular its use during…

Software Engineering · Computer Science 2016-12-06 Sebastian Baltes , Stefan Wagner

Diffusion models have emerged as powerful tools for molecular generation, particularly in the context of 3D molecular structures. Inspired by non-equilibrium statistical physics, these models can generate 3D molecular structures with…

Chemical Physics · Physics 2025-05-16 Amira Alakhdar , Barnabas Poczos , Newell Washburn

Multimodal UI design and development tools that interpret sketches or natural language descriptions of UIs inherently have notations: the inputs they can understand. In AI-based systems, notations are implicitly defined by the data used to…

Human-Computer Interaction · Computer Science 2025-08-14 Sam H. Ross , Yunseo Lee , Coco K. Lee , Jayne Everson , R. Benjamin Shapiro

For creative tasks, programmers face a choice: Use a GUI and sacrifice flexibility, or write code and sacrifice ergonomics? To obtain both flexibility and ease of use, a number of systems have explored a workflow that we call…

Human-Computer Interaction · Computer Science 2019-08-13 Brian Hempel , Justin Lubin , Ravi Chugh

Studying systems where many individual bodies in motion interact with one another is a complex and interesting area. Simple mechanisms that may be determined for biological, chemical, or physical reasons can lead to astonishingly complex…

Quantitative Methods · Quantitative Biology 2023-01-03 Cameron McNamee , Renee Reijo Pera

Molecular dynamics simulations have the potential to provide atomic-level detail and insight to important questions in chemical physics that cannot be observed in typical experiments. However, simply generating a long trajectory is…

Chemical Physics · Physics 2015-06-22 Christian R. Schwantes , Robert T. McGibbon , Vijay S. Pande

3D Gaussian representations have emerged as a powerful paradigm for digital head modeling, achieving photorealistic quality with real-time rendering. However, intuitive and interactive creation or editing of 3D Gaussian head models remains…

Graphics · Computer Science 2026-04-22 Bo Li , Jiahao Kang , Yubo Ma , Feng-Lin Liu , Bin Liu , Fang-Lue Zhang , Lin Gao

The facial sketch synthesis (FSS) model, capable of generating sketch portraits from given facial photographs, holds profound implications across multiple domains, encompassing cross-modal face recognition, entertainment, art, media, among…

Computer Vision and Pattern Recognition · Computer Science 2024-08-23 Bowen Sun , Guo Lu , Shibao Zheng

A large number of powerful, high-quality, and open-source simulation packages exist to efficiently perform molecular dynamics simulations, and their prevalence has greatly accelerated discoveries across a wide range of scientific domains.…

Soft Condensed Matter · Physics 2024-05-01 Toler H. Webb , Daniel M. Sussman

Parametric computer-aided design (CAD) tools are the predominant way that engineers specify physical structures, from bicycle pedals to airplanes to printed circuit boards. The key characteristic of parametric CAD is that design intent is…

Machine Learning · Computer Science 2022-04-29 Ari Seff , Wenda Zhou , Nick Richardson , Ryan P. Adams