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A hallmark of living systems is the ability to employ a common set of versatile building blocks that can self-organize into a multitude of different structures, in a way that can be controlled with minimal cost. This capability can only be…

Statistical Mechanics · Physics 2022-01-26 Saeed Osat , Ramin Golestanian

Assembly theory predicts that a distinguishing signature of life is its ability to produce complex molecules in abundance, opening new possibilities for life detection. Experimental validation of this approach has so far relied on abiotic…

Biological Physics · Physics 2025-09-08 Alexandre Champagne-Ruel , Christopher P. Kempes , Cole Mathis

In this paper we study aggregation kinetics in systems of particles functionalised by complementary linkers. Most of the coarse-grained models currently employed to study large-scale self-assembly of these systems rely on effective…

Soft Condensed Matter · Physics 2018-12-24 S. J. Bachmann , M. Petitzon , B. M. Mognetti

Self-assembly is traditionally described as the process through which an initially disordered system relaxes towards an equilibrium ordered phase only driven by local interactions between its building blocks. However, This definition is too…

Soft Condensed Matter · Physics 2015-06-15 Lorenzo Di Michele , Francesco Varrato , Jurij Kotar , Simon H. Nathan , Giuseppe Foffi , Erika Eiser

We consider an important class of self-assembly problems and using the formalism of stochastic thermodynamics, we derive a set of design principles for growing controlled assemblies far from equilibrium. The design principles constrain the…

Statistical Mechanics · Physics 2017-01-17 Michael Nguyen , Suriyanarayanan Vaikuntanathan

Multi-step pathways, constituted of a sequence of reconfigurations, are central to a wide variety of natural and man-made systems. Such pathways autonomously execute in self-guided processes such as protein folding and self-assembly, but…

Soft Condensed Matter · Physics 2018-10-18 Corentin Coulais , Alberico Sabbadini , Fré Vink , Martin van Hecke

In this paper, we introduce concepts of pathwise random almost periodic and almost automorphic solutions for dynamical systems generated by non-autonomous stochastic equations. These solutions are pathwise stochastic analogues of…

Dynamical Systems · Mathematics 2014-05-27 Bixiang Wang

The hallmark feature of polymorphic systems is their ability to assemble into many possible structures at the same thermodynamic state. Designer polymorphic materials can in principle be engineered via programmable self-assembly, but the…

Soft Condensed Matter · Physics 2025-05-23 Fan Chen , William M. Jacobs

Dynamical symmetries are of considerable importance in elucidating the complex behaviour of strongly interacting systems with many degrees of freedom. Paradigmatic examples are cooperative phenomena as they arise in phase transitions, where…

Mathematical Physics · Physics 2015-11-16 Malte Henkel

Self-assembly is a process which is ubiquitous in natural, especially biological systems. It occurs when groups of relatively simple components spontaneously combine to form more complex structures. While such systems have inspired a large…

Computational Geometry · Computer Science 2018-07-19 Jerome Durand-Lose , Jacob Hendricks , Matthew J. Patitz , Ian Perkins , Michael Sharp

The self-assembly of particles into organized structures is a key feature of living organisms and a major engineering challenge. While it may proceed through the binding of perfectly matched, puzzle-pieces-like particles, many other…

Soft Condensed Matter · Physics 2024-04-08 Hugo Le Roy , M. Mert Terzi , Martin lenz

Active self-assembly can bypass equilibrium bottlenecks through external energy injection. However, generic driving typically distorts target structures and requires sustained energy input even after assembly is complete. Here, we…

Soft Condensed Matter · Physics 2026-04-27 Dawid Dopierała , Luca Cocconi , Robert L. Jack , Anton Souslov

For spatiotemporal chaos described by partial differential equations, there are generally locations where the dynamical variable achieves its local extremum or where the time partial derivative of the variable vanishes instantaneously. To a…

Chaotic Dynamics · Physics 2013-03-07 Quntao Zhuang , Xun Gao , Qi Ouyang , Hongli Wang

Self-organization creates new order and shifts sub-boundaries while reorganizing energy and entropy within a control volume. This article examines pathway selection and tests whether maximizing the entropy generation rate can forecast…

Materials Science · Physics 2026-03-10 J. A. Sekhar

Understanding protein self-assembly is important for many biological and industrial processes. Proteins can self-assemble into crystals, filaments, gels, and other amorphous aggregates. The final forms include virus capsids and condensed…

Soft Condensed Matter · Physics 2016-04-15 Jennifer J. McManus , Patrick Charbonneau , Emanuela Zaccarelli , Neer Asherie

The design of desired behaviors in mechanical metamaterials has produced remarkable advances but has generally neglected two aspects - the inevitable presence of undesired behaviors and the role of dynamics in avoiding such behaviors.…

Soft Condensed Matter · Physics 2019-10-22 Menachem Stern , Viraaj Jayaram , Arvind Murugan

The self-assembly of functionalized (patchy) particles with directional interactions into target structures is still a challenge, despite the significant experimental advances on their synthesis. The self-assembly pathways are typically…

Soft Condensed Matter · Physics 2018-01-17 Cristóvão S. Dias , Nuno A. M. Araújo , Margarida M. Telo da Gama

In the so-called "microscopic" models of vehicular traffic, attention is paid explicitly to each individual vehicle each of which is represented by a "particle"; the nature of the "interactions" among these particles is determined by the…

Statistical Mechanics · Physics 2009-10-31 Debashish Chowdhury , Ludger Santen , Andreas Schadschneider

Self-assembly is the mechanism that controls the formation of well defined structures from disordered pre-existing parts. Despite the importance of self-assembly as a manufacturing method and the increasingly large number of experimental…

Soft Condensed Matter · Physics 2007-08-15 Emanuela Bianchi , Emilia La Nave , Piero Tartaglia , Francesco Sciortino

Protein folding, peptide aggregation and crystallization, as well as adsorption of molecules on soft or solid substrates have an essential feature in common: In all these processes, structure formation is guided by a collective, cooperative…

Statistical Mechanics · Physics 2009-02-12 Michael Bachmann , Wolfhard Janke