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Large-scale population-based studies in medicine are a key resource towards better diagnosis, monitoring, and treatment of diseases. They also serve as enablers of clinical decision support systems, in particular Computer Aided Diagnosis…

Machine Learning · Computer Science 2022-03-01 Gerome Vivar , Anees Kazi , Hendrik Burwinkel , Andreas Zwergal , Nassir Navab , Seyed-Ahmad Ahmadi

In genome wide association studies (GWAS), researchers are often dealing with non-normally distributed traits or a mixture of discrete-continuous traits. However, most of the current region-based methods rely on multivariate linear mixed…

Methodology · Statistics 2021-09-30 Julien St-Pierre , Karim Oualkacha

A multiple-perspective co-citation analysis method is introduced for characterizing and interpreting the structure and dynamics of co-citation clusters. The method facilitates analytic and sense making tasks by integrating network…

Computers and Society · Computer Science 2017-10-24 Chaomei Chen , Fidelia Ibekwe-SanJuan , Jianhua Hou

Canonical correlation analysis is a family of multivariate statistical methods for the analysis of paired sets of variables. Since its proposition, canonical correlation analysis has for instance been extended to extract relations between…

Machine Learning · Computer Science 2017-11-08 Viivi Uurtio , João M. Monteiro , Jaz Kandola , John Shawe-Taylor , Delmiro Fernandez-Reyes , Juho Rousu

Principal Component analysis (PCA) is a useful statistical technique that is commonly used for multivariate analysis of correlated variables. It is usually applied as a dimension reduction method: the top principal components (PCs)…

Coarse-grained (CG) modeling simplifies molecular systems by mapping groups of atoms into representative units. However, traditional CG approaches rely on fixed mapping rules, which limit their ability to handle diverse chemical systems and…

Computational Physics · Physics 2025-09-26 Zhixuan Zhong , Linbo Ma , Jian Jiang

A core task in multi-modal learning is to integrate information from multiple feature spaces (e.g., text and audio), offering modality-invariant essential representations of data. Recent research showed that, classical tools such as {\it…

Machine Learning · Computer Science 2024-10-02 Subash Timilsina , Sagar Shrestha , Xiao Fu

Multivariate Functional Principal Component Analysis (MFPCA) is a valuable tool for exploring relationships and identifying shared patterns of variation in multivariate functional data. However, controlling the roughness of the extracted…

Methodology · Statistics 2023-06-27 Hossein Haghbin , Yue Zhao , Mehdi Maadooliat

Semi-supervised learning has become increasingly popular in medical image segmentation due to its ability to leverage large amounts of unlabeled data to extract additional information. However, most existing semi-supervised segmentation…

Computer Vision and Pattern Recognition · Computer Science 2023-07-13 Shengbo Gao , Ziji Zhang , Jiechao Ma , Zihao Li , Shu Zhang

Feature extraction and dimensionality reduction are important tasks in many fields of science dealing with signal processing and analysis. The relevance of these techniques is increasing as current sensory devices are developed with ever…

Machine Learning · Statistics 2013-10-21 Jerónimo Arenas-García , Kaare Brandt Petersen , Gustavo Camps-Valls , Lars Kai Hansen

We propose a novel algorithm for supervised dimensionality reduction named Manifold Partition Discriminant Analysis (MPDA). It aims to find a linear embedding space where the within-class similarity is achieved along the direction that is…

Machine Learning · Computer Science 2020-11-24 Yang Zhou , Shiliang Sun

Root cause analysis (RCA) in microservice systems is challenging, requiring on-call engineers to rapidly diagnose failures across heterogeneous telemetry such as metrics, logs, and traces. Traditional RCA methods often focus on single…

Artificial Intelligence · Computer Science 2025-08-19 Yifang Tian , Yaming Liu , Zichun Chong , Zihang Huang , Hans-Arno Jacobsen

Recent developments in regularized Canonical Correlation Analysis (CCA) promise powerful methods for high-dimensional, multiview data analysis. However, justifying the structural assumptions behind many popular approaches remains a…

Methodology · Statistics 2025-11-18 Lennie Wells , Kumar Thurimella , Sergio Bacallado

This paper proposes multivariate copula models for hierarchical data. They account for two types of correlation: one is between variables measured on the same unit and the other is a correlation between units in the same cluster. This model…

Methodology · Statistics 2023-04-24 Talagbe Gabin Akpo , Louis-Paul Rivest

Colocalization analysis aims to study complex spatial associations between bio-molecules via optical imaging techniques. However, existing colocalization analysis workflows only assess an average degree of colocalization within a certain…

Principal component analysis (PCA) is a dimensionality reduction method in data analysis that involves diagonalizing the covariance matrix of the dataset. Recently, quantum algorithms have been formulated for PCA based on diagonalizing a…

Quantum Physics · Physics 2022-10-26 Max Hunter Gordon , M. Cerezo , Lukasz Cincio , Patrick J. Coles

In this paper, we propose an effective feature extraction algorithm, called Multi-Subregion based Correlation Filter Bank (MS-CFB), for robust face recognition. MS-CFB combines the benefits of global-based and local-based feature extraction…

Computer Vision and Pattern Recognition · Computer Science 2016-03-25 Yan Yan , Hanzi Wang , David Suter

Canonical correlation analysis (CCA) is a classical and important multivariate technique for exploring the relationship between two sets of continuous variables. CCA has applications in many fields, such as genomics and neuroimaging. It can…

Methodology · Statistics 2020-05-12 Lin Qiu , Vernon M. Chinchilli

Correspondence analysis (CA) is a multivariate statistical tool used to visualize and interpret data dependencies. CA has found applications in fields ranging from epidemiology to social sciences. However, current methods used to perform CA…

Machine Learning · Statistics 2019-02-22 Hsiang Hsu , Salman Salamatian , Flavio P. Calmon

Canonical Correlation Analysis (CCA) is a linear representation learning method that seeks maximally correlated variables in multi-view data. Non-linear CCA extends this notion to a broader family of transformations, which are more powerful…

Machine Learning · Computer Science 2020-02-11 Amichai Painsky , Meir Feder , Naftali Tishby