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The standard methods for detecting differential gene expression are mostly designed for analyzing a single gene expression experiment. When data from multiple related gene expression studies are available, separately analyzing each study is…

Methodology · Statistics 2013-11-07 Yingying Wei , Hongkai Ji

Manifold matching works to identify embeddings of multiple disparate data spaces into the same low-dimensional space, where joint inference can be pursued. It is an enabling methodology for fusion and inference from multiple and massive…

Machine Learning · Statistics 2012-09-18 Ming Sun , Carey E. Priebe , Minh Tang

Envelope model also known as multivariate regression model was proposed to solve the multiple response regression problems. It measures the linear association between predictors and multiple responses by using the minimal reducing subspace…

Methodology · Statistics 2018-05-07 Bochao Jia

The classical Canonical Correlation Analysis (CCA) identifies the correlations between two sets of multivariate variables based on their covariance, which has been widely applied in diverse fields such as computer vision, natural language…

Optimization and Control · Mathematics 2024-01-02 Yongchun Li , Santanu S. Dey , Weijun Xie

We propose Cooperative Component Analysis (CoCA), a new method for unsupervised multi-view analysis: it identifies the component that simultaneously captures significant within-view variance and exhibits strong cross-view correlation. The…

Methodology · Statistics 2024-07-25 Daisy Yi Ding , Alden Green , Min Woo Sun , Robert Tibshirani

Identifying relationships between molecular variations and their clinical presentations has been challenged by the heterogeneous causes of a disease. It is imperative to unveil the relationship between the high dimensional molecular…

Methodology · Statistics 2021-09-02 Wennan Chang , Changlin Wan , Yong Zang , Chi Zhang , Sha Cao

Multi-view data are increasingly prevalent in practice. It is often relevant to analyze the relationships between pairs of views by multi-view component analysis techniques such as Canonical Correlation Analysis (CCA). However, data may…

Machine Learning · Statistics 2019-12-10 Eric Lei , Kyle Miller , Michael R. Pinsky , Artur Dubrawski

The idea of representation has been used in various fields of study from data analysis to political science. In this paper, we define representativeness and describe a method to isolate data points that can represent the entire data set.…

Information Retrieval · Computer Science 2016-10-20 Ashwinkumar Ganesan , Tim Oates , Matt Schmill

Multimodal manifold modeling methods extend the spectral geometry-aware data analysis to learning from several related and complementary modalities. Most of these methods work based on two major assumptions: 1) there are the same number of…

Machine Learning · Computer Science 2021-05-13 Maysam Behmanesh , Peyman Adibi , Jocelyn Chanussot , Sayyed Mohammad Saeed Ehsani

With advances in neural recording techniques, neuroscientists are now able to record the spiking activity of many hundreds of neurons simultaneously, and new statistical methods are needed to understand the structure of this large-scale…

Neurons and Cognition · Quantitative Biology 2023-03-03 Ganchao Wei , Ian H. Stevenson , Xiaojing Wang

Over the years, Principal Component Analysis (PCA) has served as the baseline approach for dimensionality reduction in gene expression data analysis. It primary objective is to identify a subset of disease-causing genes from a vast pool of…

Algebraic Topology · Mathematics 2023-06-13 Sean Cottrell , Rui Wang , Guowei Wei

To understand the biology of cancer, joint analysis of multiple data modalities, including imaging and genomics, is crucial. The involved nature of gene-microenvironment interactions necessitates the use of algorithms which treat both data…

Signal Processing · Electrical Eng. & Systems 2018-02-27 Vaishnavi Subramanian , Benjamin Chidester , Jian Ma , Minh N. Do

Root Cause Analysis (RCA) aims at identifying the underlying causes of system faults by uncovering and analyzing the causal structure from complex systems. It has been widely used in many application domains. Reliable diagnostic conclusions…

Artificial Intelligence · Computer Science 2024-07-15 Chang Gong , Di Yao , Jin Wang , Wenbin Li , Lanting Fang , Yongtao Xie , Kaiyu Feng , Peng Han , Jingping Bi

Canonical Correlation Analysis (CCA) is a classical tool for finding correlations among the components of two random vectors. In recent years, CCA has been widely applied to the analysis of genomic data, where it is common for researchers…

Machine Learning · Computer Science 2012-06-22 Sivaraman Balakrishnan , Kriti Puniyani , John Lafferty

Canonical correlation analysis is a statistical technique that is used to find relations between two sets of variables. An important extension in pattern analysis is to consider more than two sets of variables. This problem can be expressed…

Machine Learning · Computer Science 2013-02-06 Jan Rupnik , Primoz Skraba , John Shawe-Taylor , Sabrina Guettes

Most multi-view clustering methods are limited by shallow models without sound nonlinear information perception capability, or fail to effectively exploit complementary information hidden in different views. To tackle these issues, we…

Machine Learning · Computer Science 2022-10-14 Fu Lele , Zhang Lei , Yang Jinghua , Chen Chuan , Zhang Chuanfu , Zheng Zibin

Correspondence analysis (CA) is a multivariate statistical tool used to visualize and interpret data dependencies by finding maximally correlated embeddings of pairs of random variables. CA has found applications in fields ranging from…

Machine Learning · Computer Science 2020-07-01 Hsiang Hsu , Salman Salamatian , Flavio P. Calmon

A new approach to the sparse Canonical Correlation Analysis (sCCA)is proposed with the aim of discovering interpretable associations in very high-dimensional multi-view, i.e.observations of multiple sets of variables on the same subjects,…

Machine Learning · Statistics 2019-09-18 Omid S. Solari , James B. Brown , Peter J. Bickel

Canonical Correlation Analysis (CCA) is a widespread technique for discovering linear relationships between two sets of variables $X \in \mathbb{R}^{n \times p}$ and $Y \in \mathbb{R}^{n \times q}$. In high dimensions however, standard…

Methodology · Statistics 2024-05-31 Claire Donnat , Elena Tuzhilina

This paper is concerned with the analysis of correlation between two high-dimensional data sets when there are only few correlated signal components but the number of samples is very small, possibly much smaller than the dimensions of the…

Information Theory · Computer Science 2016-04-08 Yang Song , Peter J. Schreier , David Ramirez , Tanuj Hasija