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Segmentation is essential for medical image analysis tasks such as intervention planning, therapy guidance, diagnosis, treatment decisions. Deep learning is becoming increasingly prominent for segmentation, where the lack of annotations,…

Computer Vision and Pattern Recognition · Computer Science 2019-03-19 Firat Ozdemir , Zixuan Peng , Christine Tanner , Philipp Fuernstahl , Orcun Goksel

A collaborative network is a social network that is comprised of experts who cooperate with each other to fulfill a special goal. Analyzing this network yields meaningful information about the expertise of these experts and their subject…

Social and Information Networks · Computer Science 2021-04-14 N. Nikzad-Khasmakhi , M. A. Balafar , M. Reza Feizi-Derakhshi , Cina Motamed

Graph-based machine learning methods are useful tools in the identification and prediction of variation in genetic data. In particular, the comprehension of phenotypic effects at the cellular level is an accelerating research area in…

Quantitative Methods · Quantitative Biology 2024-12-06 Nandini Gadhia , Michalis Smyrnakis , Po-Yu Liu , Damer Blake , Melanie Hay , Anh Nguyen , Dominic Richards , Dong Xia , Ritesh Krishna

Contemporary techniques in biology produce readouts for large numbers of genes simultaneously, the typical example being differential gene expression measurements. Moreover, those genes are often richly annotated using GO terms that…

Genomics · Quantitative Biology 2016-02-24 Fran Supek , Nives Škunca

Knowledge base construction is crucial for summarising, understanding and inferring relationships between biomedical entities. However, for many practical applications such as drug discovery, the scarcity of relevant facts (e.g. gene X is…

Computation and Language · Computer Science 2019-07-04 Julien Fauqueur , Ashok Thillaisundaram , Theodosia Togia

Image segmentation is a fundamental problem in biomedical image analysis. Recent advances in deep learning have achieved promising results on many biomedical image segmentation benchmarks. However, due to large variations in biomedical…

Computer Vision and Pattern Recognition · Computer Science 2017-06-16 Lin Yang , Yizhe Zhang , Jianxu Chen , Siyuan Zhang , Danny Z. Chen

Development of deep learning systems for biomedical segmentation often requires access to expert-driven, manually annotated datasets. If more than a single expert is involved in the annotation of the same images, then the inter-expert…

The performance of current supervised AI systems is tightly connected to the availability of annotated datasets. Annotations are usually collected through annotation tools, which are often designed for specific tasks and are difficult to…

Human-Computer Interaction · Computer Science 2023-05-24 Naihao Deng , Yikai Liu , Mingye Chen , Winston Wu , Siyang Liu , Yulong Chen , Yue Zhang , Rada Mihalcea

Modular structure is pervasive in many complex networks of interactions observed in natural, social and technological sciences. Its study sheds light on the relation between the structure and function of complex systems. Generally speaking,…

Data Analysis, Statistics and Probability · Physics 2010-05-10 Alex Arenas , Javier Borge-Holthoefer , Sergio Gomez , Gorka Zamora-Lopez

Machine Learning algorithms are increasingly being used in recent years due to their flexibility in model fitting and increased predictive performance. However, the complexity of the models makes them hard for the data analyst to interpret…

Machine Learning · Statistics 2018-06-07 Joel Vaughan , Agus Sudjianto , Erind Brahimi , Jie Chen , Vijayan N. Nair

Collecting annotations from multiple independent sources could mitigate the impact of potential noises and biases from a single source, which is a common practice in medical image segmentation. Learning segmentation networks from…

Image and Video Processing · Electrical Eng. & Systems 2023-11-14 Yifeng Wang , Luyang Luo , Mingxiang Wu , Qiong Wang , Hao Chen

Large software projects are among most sophisticated human-made systems consisting of a network of interdependent parts. Past studies of software systems from the perspective of complex networks have already led to notable discoveries with…

Social and Information Networks · Computer Science 2015-05-21 Lovro Šubelj , Slavko Žitnik , Neli Blagus , Marko Bajec

Nowadays, due to the increasing amount of experimental data obtained by sequencing, the most interest is focused on determining the functions and characteristics of its individual parts of the genome instead of determining the nucleotide…

Genomics · Quantitative Biology 2021-02-09 Marina Galchenkova , Aleksei Korzhenkov

Fluorescence microscopy allows for a detailed inspection of cells, cellular networks, and anatomical landmarks by staining with a variety of carefully-selected markers visualized as color channels. Quantitative characterization of…

Computer Vision and Pattern Recognition · Computer Science 2021-08-26 Alvaro Gomariz , Tiziano Portenier , Patrick M. Helbling , Stephan Isringhausen , Ute Suessbier , César Nombela-Arrieta , Orcun Goksel

Many real-world applications require automated data annotation, such as identifying tissue origins based on gene expressions and classifying images into semantic categories. Annotation classes are often numerous and subject to changes over…

Computation and Language · Computer Science 2018-07-03 Maxim Grechkin , Hoifung Poon , Bill Howe

The aim of this paper is threefold. We inform the AI practitioner about the human visual system with an extensive literature review; we propose a novel biologically motivated neural network for image classification; and, finally, we present…

Computer Vision and Pattern Recognition · Computer Science 2024-09-09 Gianluca Carloni , Sara Colantonio

A graph with semantically attributed nodes are a common data structure in a wide range of domains. It could be interlinked web data or citation networks of scientific publications. The essential problem for such a data type is to determine…

Machine Learning · Computer Science 2025-12-09 Elizaveta Kovtun , Maksim Makarenko , Natalia Semenova , Alexey Zaytsev , Semen Budennyy

Network embedding, which aims to learn low-dimensional representations of nodes, has been used for various graph related tasks including visualization, link prediction and node classification. Most existing embedding methods rely solely on…

Social and Information Networks · Computer Science 2019-08-22 Palash Goyal , Homa Hosseinmardi , Emilio Ferrara , Aram Galstyan

Systems biology approaches to the integrative study of cells, organs and organisms offer the best means of understanding in a holistic manner the diversity of molecular assays that can be now be implemented in a high throughput manner. Such…

Quantitative Methods · Quantitative Biology 2016-11-15 David Rhee , Kevin Shieh , Julie Sullivan , Gos Micklem , Kami Kim , Aaron Golden

Objective: Human-curated disease ontologies are widely used for diagnostic evaluation, treatment and data comparisons over time, and clinical decision support. The classification principles underlying these ontologies are guided by the…

Molecular Networks · Quantitative Biology 2021-04-02 Giorgio Grani , Lorenzo Madeddu , Paola Velardi