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Tracking of plant cells in images obtained by microscope is a challenging problem due to biological phenomena such as large number of cells, non-uniform growth of different layers of the tightly packed plant cells and cell division.…

Computer Vision and Pattern Recognition · Computer Science 2023-09-22 Md Shazid Islam , Arindam Dutta , Calvin-Khang Ta , Kevin Rodriguez , Christian Michael , Mark Alber , G. Venugopala Reddy , Amit K. Roy-Chowdhury

Automatic cell image segmentation methods in connectomics produce merge and split errors, which require correction through proofreading. Previous research has identified the visual search for these errors as the bottleneck in interactive…

Computer Vision and Pattern Recognition · Computer Science 2017-04-05 Daniel Haehn , Verena Kaynig , James Tompkin , Jeff W. Lichtman , Hanspeter Pfister

Reconstruction of neuroanatomy is a fundamental problem in neuroscience. Stochastic expression of colors in individual cells is a promising tool, although its use in the nervous system has been limited due to various sources of variability…

Neurons and Cognition · Quantitative Biology 2017-01-24 Uygar Sümbül , Douglas Roussien , Fei Chen , Nicholas Barry , Edward S. Boyden , Dawen Cai , John P. Cunningham , Liam Paninski

We present a novel automated method to segment the myocardium of both left and right ventricles in MRI volumes. The segmentation is consistent in 3D across the slices such that it can be directly used for mesh generation. Two specific…

Computer Vision and Pattern Recognition · Computer Science 2018-03-30 Qiao Zheng , Hervé Delingette , Nicolas Duchateau , Nicholas Ayache

In this work, we utilize image segmentation to visually identify blood vessels in retinal examination images. This process is typically carried out manually. However, we can employ heuristic methods and machine learning to automate or at…

Image and Video Processing · Electrical Eng. & Systems 2023-09-01 João Henrique Pereira Machado , Gilson Adamczuk Oliveira , Érick Oliveira Rodrigues

Convolutional Neural Networks (CNNs) have been recently employed to solve problems from both the computer vision and medical image analysis fields. Despite their popularity, most approaches are only able to process 2D images while most…

Computer Vision and Pattern Recognition · Computer Science 2016-06-16 Fausto Milletari , Nassir Navab , Seyed-Ahmad Ahmadi

Recently, several image segmentation methods that welcome and leverage different types of user assistance have been developed. In these methods, the user inputs can be provided by drawing bounding boxes over image objects, drawing scribbles…

Computer Vision and Pattern Recognition · Computer Science 2022-04-06 Huseyin Afser

Image segmentation plays an essential role in medicine for both diagnostic and interventional tasks. Segmentation approaches are either manual, semi-automated or fully-automated. Manual segmentation offers full control over the quality of…

Computer Vision and Pattern Recognition · Computer Science 2019-03-21 Tomas Sakinis , Fausto Milletari , Holger Roth , Panagiotis Korfiatis , Petro Kostandy , Kenneth Philbrick , Zeynettin Akkus , Ziyue Xu , Daguang Xu , Bradley J. Erickson

Segmentation of blood vessels in murine cerebral 3D OCTA images is foundational for in vivo quantitative analysis of the effects of neurovascular disorders, such as stroke or Alzheimer's, on the vascular network. However, to accurately…

Image and Video Processing · Electrical Eng. & Systems 2024-03-13 Bastian Wittmann , Lukas Glandorf , Johannes C. Paetzold , Tamaz Amiranashvili , Thomas Wälchli , Daniel Razansky , Bjoern Menze

3D volume segmentation is a fundamental task in many scientific and medical applications. Producing accurate segmentations efficiently is challenging, in part due to low imaging data quality (e.g., noise and low image resolution) and…

Human-Computer Interaction · Computer Science 2020-04-08 Anahita Sanandaji , Cindy Grimm , Ruth West , Max Parola , Meghan Kajihara , Kathryn Hays , Luke Hillard , Brandon Lane , Molly Beyer

Computational fluid dynamics (CFD) can be used for evaluation of hemodynamics. However, its routine use is limited by labor-intensive manual segmentation, CFD mesh creation, and time-consuming simulation. This study aims to train a deep…

Computer Vision and Pattern Recognition · Computer Science 2025-02-18 Tina Yao , Endrit Pajaziti , Michael Quail , Silvia Schievano , Jennifer A Steeden , Vivek Muthurangu

We propose a cell segmentation method for analyzing images of densely clustered cells. The method combines the strengths of marker-controlled watershed transformation and a convolutional neural network (CNN). We demonstrate the method…

Image and Video Processing · Electrical Eng. & Systems 2020-04-06 Filip Lux , Petr Matula

Recent advances in electron microscopy have enabled the imaging of single cells in 3D at nanometer length scale resolutions. An uncharted frontier for in silico biology is the ability to simulate cellular processes using these observed…

Many end-user evaluations of data visualization techniques have been run during the last decades. Their results are cornerstones to build efficient visualization systems. However, designing such an evaluation is always complex and…

Human-Computer Interaction · Computer Science 2020-04-20 L. Giovannangeli , R. Bourqui , R. Giot , D. Auber

We present a dual-stage neural network architecture for analyzing fine shape details from microscopy recordings in 3D. The system, tested on red blood cells, uses training data from both healthy donors and patients with a congenital blood…

Quantitative Methods · Quantitative Biology 2020-05-29 G. Simionato , K. Hinkelmann , R. Chachanidze , P. Bianchi , E. Fermo , R. van Wijk , M. Leonetti , C. Wagner , L. Kaestner , S. Quint

The quantitative analysis of cellular membranes helps understanding developmental processes at the cellular level. Particularly 3D microscopic image data offers valuable insights into cell dynamics, but error-free automatic segmentation…

Computer Vision and Pattern Recognition · Computer Science 2018-10-17 Dennis Eschweiler , Thiago V. Spina , Rohan C. Choudhury , Elliot Meyerowitz , Alexandre Cunha , Johannes Stegmaier

Tracking cells in 3D at high speed continues to attract extensive attention for many biomedical applications, such as monitoring immune cell migration and observing tumor metastasis in flowing blood vessels. Here, we propose a deep…

Optics · Physics 2018-05-16 Kan Liu , Hui Qiao , Jiamin Wu , Haoqian Wang , Lu Fang , Qionghai Dai

Tracking many cells in time-lapse 3D image sequences is an important challenging task of bioimage informatics. Motivated by a study of brain-wide 4D imaging of neural activity in C. elegans, we present a new method of multi-cell tracking.…

Computer Vision and Pattern Recognition · Computer Science 2018-01-18 Osamu Hirose , Shotaro Kawaguchi , Terumasa Tokunaga , Yu Toyoshima , Takayuki Teramoto , Sayuri Kuge , Takeshi Ishihara , Yuichi Iino , Ryo Yoshida

Cellular electron cryo-tomography enables the 3D visualization of cellular organization in the near-native state and at submolecular resolution. However, the contents of cellular tomograms are often complex, making it difficult to…

Quantitative Methods · Quantitative Biology 2017-12-29 Xiangrui Zeng , Miguel Ricardo Leung , Tzviya Zeev-Ben-Mordehai , Min Xu

We propose a fully automatic system to reconstruct and visualize 3D blood vessels in Augmented Reality (AR) system from stereo X-ray images with bones and body fat. Currently, typical 3D imaging technologies are expensive and carrying the…

Computer Vision and Pattern Recognition · Computer Science 2017-09-25 Qiuyu Chen , Ryoma Bise , Lin Gu , Yinqiang Zheng , Imari Sato , Jenq-Neng Hwang , Nobuaki Imanishi , Sadakazu Aiso