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Background: Recent models of genome-proteome evolution have shown that some of the key traits displayed by the global structure of cellular networks might be a natural result of a duplication-diversification (DD) process. One of the…

Genomics · Quantitative Biology 2007-05-23 Ricard V. Sole , Pau Fernandez

Understanding how the structure of community interactions is modified by coevolution is vital for understanding system responses to change at all scales. However, in absence of a group selection process, collective community behaviours…

Populations and Evolution · Quantitative Biology 2015-06-23 Daniel A. Power , Richard A. Watson , Eörs Szathmáry , Rob Mills , Simon T Powers , C Patrick Doncaster , Błażej Czapp

Biological approximations, which are universal for diverse species, are well known. With no other experimental data, their invariance to transformations from one species to another yields exact conservation (with respect to biological…

Statistical Mechanics · Physics 2007-05-23 Mark Ya. Azbel'

Biological networks such as gene regulatory networks possess desirable properties. They are more robust and controllable than random networks. This motivates the search for structural and dynamical features that evolution has incorporated…

Molecular Networks · Quantitative Biology 2024-02-16 Claus Kadelka , David Murrugarra

Theoretical analysis proves that human survivability is dominated by an unusual physical, rather than biological, mechanism, which yields an exact law. The law agrees with all experimental data, but, contrary to existing theories, it is the…

Biological Physics · Physics 2009-11-07 Mark Ya. Azbel'

Despite the obvious advantage of simple life forms capable of fast replication, different levels of cognitive complexity have been achieved by living systems in terms of their potential to cope with environmental uncertainty. Against the…

Populations and Evolution · Quantitative Biology 2017-10-18 Luís F Seoane , Ricard Solé

Reduction of information entropy along with ever-increasing complexity are among the key signatures of living matter. Understanding the onset of such behavior in early prebiotic world is essential for solving the problem of origins of life.…

Populations and Evolution · Quantitative Biology 2018-10-17 Alexei V. Tkachenko , Sergei Maslov

Many biological phenomena or social events critically depend on how information evolves in complex networks. However, a general theory to characterize information evolution is yet absent. Consequently, numerous unknowns remain about the…

Biological Physics · Physics 2022-07-20 Yang Tian , Guoqi Li , Pei Sun

The Darwinian paradigm of biological evolution is based on the separability of the variation and selection processes. As a result, the population thinking had always been an integral part of the Darwinian approach. I propose an alternative…

Other Quantitative Biology · Quantitative Biology 2007-05-23 Vasily Ogryzko

Modern generative machine learning models demonstrate surprising ability to create realistic outputs far beyond their training data, such as photorealistic artwork, accurate protein structures, or conversational text. These successes…

Machine Learning · Computer Science 2024-01-17 William Gilpin

Significant fraction (about 98.5% in humans, 24% in microbe Rickettsia prowazekii) of most animal genomes is non-coding DNA. Although recent studies established functions of its certain portions, it remains genomic dark matter. The paper…

Genomics · Quantitative Biology 2007-05-23 Mark Ya. Azbel

It has been hypothesized that one of the main reasons evolution has been able to produce such impressive adaptations is because it has improved its own ability to evolve -- "the evolution of evolvability". Rupert Riedl, for example, an…

Populations and Evolution · Quantitative Biology 2016-12-20 Loizos Kounios , Jeff Clune , Kostas Kouvaris , Günter P. Wagner , Mihaela Pavlicev , Daniel M. Weinreich , Richard A. Watson

A self-replicator is usually understood to be an object of definite form that promotes the conversion of materials in its environment into a nearly identical copy of itself. The challenge of engineering novel, micro- or nano-scale…

Soft Condensed Matter · Physics 2019-09-04 Sumantra Sarkar , Jeremy L. England

Dawkins' replicator-based conception of evolution has led to widespread mis-application selectionism across the social sciences because it does not address the paradox that inspired the theory of natural selection in the first place: how do…

Populations and Evolution · Quantitative Biology 2019-07-02 Liane Gabora

Culture evolves, not just in the trivial sense that cultures change over time, but also in the strong sense that such change is governed by Darwinian principles. Both biological and cultural evolution are essentially cumulative selection…

Populations and Evolution · Quantitative Biology 2016-09-16 Chris Buskes

We demonstrate with a thought experiment that fitness-based population dynamical approaches to evolution are not able to make quantitative, falsifiable predictions about the long-term behavior of evolutionary systems. A key characteristic…

Populations and Evolution · Quantitative Biology 2015-05-14 Peter Klimek , Stefan Thurner , Rudolf Hanel

In both natural and artificial studies, evolution is often seen as synonymous to natural selection. Individuals evolve under pressures set by environments that are either reset or do not carry over significant changes from previous…

Populations and Evolution · Quantitative Biology 2023-05-17 Eleni Nisioti , Clément Moulin-Frier

Although Darwinian models are rampant in the social sciences, social scientists do not face the problem that motivated Darwin's theory of natural selection: the problem of explaining how lineages evolve despite that any traits they acquire…

Populations and Evolution · Quantitative Biology 2019-07-09 Liane Gabora

Organisms result from adaptive processes interacting across different time scales. One such interaction is that between development and evolution. Models have shown that development sweeps over several traits in a single agent, sometimes…

Populations and Evolution · Quantitative Biology 2018-09-19 Sam Kriegman , Nick Cheney , Josh Bongard

A new model for generating survival trajectories and data based on applying an autoencoder of a specific structure is proposed. It solves three tasks. First, it provides predictions in the form of the expected event time and the survival…

Machine Learning · Computer Science 2024-02-20 Andrei V. Konstantinov , Stanislav R. Kirpichenko , Lev V. Utkin
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