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This thesis investigates the design of algorithms for solving min-max optimization problems, which form the mathematical foundation of many modern applications in machine learning, game theory, and optimization. This work offers new…

Optimization and Control · Mathematics 2025-12-16 Sayantan Choudhury

Algorithmic discrimination is an important aspect when data is used for predictive purposes. This paper analyzes the relationships between discrimination and classification, data set partitioning, and decision models, as well as…

Computers and Society · Computer Science 2018-11-08 Jixue Liu , Jiuyong Li , Feiyue Ye , Lin Liu , Thuc Duy Le , Ping Xiong

Biomolecular networks have already found great utility in characterizing complex biological systems arising from pair-wise interactions amongst biomolecules. Here, we review how graph theoretical approaches can be applied not only for a…

Molecular Networks · Quantitative Biology 2018-12-03 Heeralal Janwa , Steven E. Massey , Julian Velev , Bud Mishra

In the real world, most objects and data have multiple types of attributes and inter-connections. Such data structures are named "Heterogeneous Information Networks" (HIN) and have been widely researched. Biological systems are also…

Molecular Networks · Quantitative Biology 2017-12-27 Koki Tsuyuzaki , Itoshi Nikaido

In recent years, ideas from statistics and scientific computing have begun to interact in increasingly sophisticated and fruitful ways with ideas from computer science and the theory of algorithms to aid in the development of improved…

Data Structures and Algorithms · Computer Science 2010-10-11 Michael W. Mahoney

One of the main tasks of post-genomic informatics is to systematically investigate all molecules and their interactions within a living cell so as to understand how these molecules and the interactions between them relate to the function of…

Molecular Networks · Quantitative Biology 2007-05-23 Jing Zhao , Hong Yu , Jianhua Luo , Z. W. Cao , Yi-Xue Li

We explore the main characteristics of big brain network data that offer unique statistical challenges. The brain networks are biologically expected to be both sparse and hierarchical. Such unique characterizations put specific topological…

Neurons and Cognition · Quantitative Biology 2017-12-27 Moo K. Chung

We consider optimization problems involving the multiplication of variable matrices to be selected from a given family, which might be a discrete set, a continuous set or a combination of both. Such nonlinear, and possibly discrete,…

Optimization and Control · Mathematics 2021-03-12 Burak Kocuk

Mathematical information is essential for technical work, but its creation, interpretation, and search are challenging. To help address these challenges, researchers have developed multimodal search engines and mathematical question…

Information Retrieval · Computer Science 2025-01-15 Richard Zanibbi , Behrooz Mansouri , Anurag Agarwal

Can machine learning help discover new mathematical structures? In this article we discuss an approach to doing this which one can call "mathematical data science". In this paradigm, one studies mathematical objects collectively rather than…

History and Overview · Mathematics 2025-02-14 Michael R. Douglas , Kyu-Hwan Lee

This article highlights some of the basic concepts of bioinformatics and data mining. The major research areas of bioinformatics are highlighted. The application of data mining in the domain of bioinformatics is explained. It also…

Computational Engineering, Finance, and Science · Computer Science 2012-05-08 Khalid Raza

The fields of computing and biology have begun to cross paths in new ways. In this paper a review of the current research in biological computing is presented. Fundamental concepts are introduced and these foundational elements are explored…

Computational Engineering, Finance, and Science · Computer Science 2009-11-10 Balaji Akula , James Cusick

As the bioinformatics field grows, it must keep pace not only with new data but with new algorithms. Here we contribute a thorough analysis of 13 state-of-the-art, commonly used machine learning algorithms on a set of 165 publicly available…

Quantitative Methods · Quantitative Biology 2018-01-09 Randal S. Olson , William La Cava , Zairah Mustahsan , Akshay Varik , Jason H. Moore

The vision of Organic Computing addresses challenges that arise in the design of future information systems that are comprised of numerous, heterogeneous, resource-constrained and error-prone components or devices. Here, the notion organic…

Networking and Internet Architecture · Computer Science 2012-04-26 Ingo Scholtes , Claudio Juan Tessone

Complex networks are frequently employed to model physical or virtual complex systems. When certain entities exist across multiple systems simultaneously, unveiling their corresponding relationships across the networks becomes crucial. This…

Physics and Society · Physics 2025-04-16 Rui Tang , Ziyun Yong , Shuyu Jiang , Xingshu Chen , Yaofang Liu , Yi-Cheng Zhang , Gui-Quan Sun , Wei Wang

Bayesian network is a complete model for the variables and their relationships, it can be used to answer probabilistic queries about them. A Bayesian network can thus be considered a mechanism for automatically applying Bayes' theorem to…

Artificial Intelligence · Computer Science 2010-11-08 Jianguo Ding

The paper aims to investigate relevant computational issues of deep neural network architectures with an eye to the interaction between the optimization algorithm and the classification performance. In particular, we aim to analyze the…

Optimization and Control · Mathematics 2024-05-06 Corrado Coppola , Lorenzo Papa , Marco Boresta , Irene Amerini , Laura Palagi

This chapter introduces statistical methods used in the analysis of social networks and in the rapidly evolving parallel-field of network science. Although several instances of social network analysis in health services research have…

Physics and Society · Physics 2014-04-02 A. James O'Malley , Jukka-Pekka Onnela

This paper presents a comprehensive survey of various established mathematical models pertaining to Somitogenesis, a biological process. The study begins by revisiting and replicating the findings from prominent research papers in this…

Dynamical Systems · Mathematics 2023-10-09 Hanyu Song

Inference and prediction are fundamental to the study of complex systems, where network data are often incomplete, inaccurate or obtained indirectly. In this paper, we review recent advances in network sampling and comparison, as well as in…

Statistical Mechanics · Physics 2025-12-09 Francisco A. Rodrigues