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Early detection of dementia is crucial to devise effective interventions. Comprehensive cognitive tests, while being the most accurate means of diagnosis, are long and tedious, thus limiting their applicability to a large population,…

Computer Vision and Pattern Recognition · Computer Science 2025-05-30 Anusha A. S. , Uma Ranjan , Medha Sharma , Siddharth Dutt

Clinical SPECT-MPI images of 345 patients acquired from a dedicated cardiac SPECT in list-mode format were retrospectively employed to predict normal-dose images from low-dose data at the half, quarter, and one-eighth-dose levels. A…

Tremor is a key diagnostic feature of Parkinson's Disease (PD), Essential Tremor (ET), and other central nervous system (CNS) disorders. Clinicians or trained raters assess tremor severity with TETRAS scores by observing patients. Lacking…

Computer Vision and Pattern Recognition · Computer Science 2021-05-05 Li Zhang , Vijay Yadav , Vidya Koesmahargyo , Anzar Abbas , Isaac Galatzer-Levy

Convolutional Neural Network (CNN) has been successfully applied on classification of both natural images and medical images but not yet been applied to differentiating patients with schizophrenia from healthy controls. Given the subtle,…

Computer Vision and Pattern Recognition · Computer Science 2020-03-20 Mengjiao Hu , Kang Sim , Juan Helen Zhou , Xudong Jiang , Cuntai Guan

Early detection of Mild Cognitive Impairment (MCI) leads to early interventions to slow the progression from MCI into dementia. Deep Learning (DL) algorithms could help achieve early non-invasive, low-cost detection of MCI. This paper…

Computer Vision and Pattern Recognition · Computer Science 2024-06-25 Muath Alsuhaibani , Hiroko H. Dodge , Mohammad H. Mahoor

Automatic lesion segmentation on thoracic CT enables rapid quantitative analysis of lung involvement in COVID-19 infections. However, obtaining a large amount of voxel-level annotations for training segmentation networks is prohibitively…

Image and Video Processing · Electrical Eng. & Systems 2021-11-22 Weiyi Xie , Colin Jacobs , Jean-Paul Charbonnier , Bram van Ginneken

Objective: Optical coherence tomography (OCT) and its angiography (OCTA) have several advantages for the early detection and diagnosis of diabetic retinopathy (DR). However, automated, complete DR classification frameworks based on both OCT…

Image and Video Processing · Electrical Eng. & Systems 2020-09-28 Pengxiao Zang , Liqin Gao , Tristan T. Hormel , Jie Wang , Qisheng You , Thomas S. Hwang , Yali Jia

A significant number of people are suffering from cognitive impairment all over the world. Early detection of cognitive impairment is of great importance to both patients and caregivers. However, existing approaches have their shortages,…

Computer Vision and Pattern Recognition · Computer Science 2021-11-10 Zixiang Fei , Erfu Yang , Leijian Yu , Xia Li , Huiyu Zhou , Wenju Zhou

In this work we show that the classification performance of high-dimensional structural MRI data with only a small set of training examples is improved by the usage of dimension reduction methods. We assessed two different dimension…

Machine Learning · Computer Science 2015-05-27 Andreas Grünauer , Markus Vincze

A plethora of deep learning models have been developed for the task of Alzheimer's disease classification from brain MRI scans. Many of these models report high performance, achieving three-class classification accuracy of up to 95%.…

Computer Vision and Pattern Recognition · Computer Science 2019-04-18 Ziqiang Guan , Ritesh Kumar , Yi Ren Fung , Yeahuay Wu , Madalina Fiterau

Automatic diagnosis of coronary heart disease helps the doctor to support in decision making a diagnosis. Coronary heart disease have some types or levels. Referring to the UCI Repository dataset, it divided into 4 types or levels that are…

Machine Learning · Computer Science 2015-11-17 Wiharto Wiharto , Hari Kusnanto , Herianto Herianto

Saliency maps have been widely used to interpret deep learning classifiers for Alzheimer's disease (AD). However, since AD is heterogeneous and has multiple subtypes, the pathological mechanism of AD remains not fully understood and may…

Computer Vision and Pattern Recognition · Computer Science 2024-07-12 Yihan Zhang , Xuanshuo Zhang , Wei Wu , Haohan Wang

Alzheimer's Disease is a neurodegenerative condition characterized by dementia and impairment in neurological function. The study primarily focuses on the individuals above age 40, affecting their memory, behavior, and cognitive processes…

Computer Vision and Pattern Recognition · Computer Science 2025-01-20 Mohammad Rafsan , Tamer Oraby , Upal Roy , Sanjeev Kumar , Hansapani Rodrigo

Obsessive-compulsive disorder (OCD) presents itself as a highly debilitating disorder. The disorder has common associations with the prefrontal cortex and the glutamate receptor known as Metabotropic Glutamate Receptor 5 (mGluR5). This…

Neurons and Cognition · Quantitative Biology 2023-08-08 Tarun Eswar

In the complex realm of cognitive disorders, Alzheimer's disease (AD) and vascular dementia (VaD) are the two most prevalent dementia types, presenting entangled symptoms yet requiring distinct treatment approaches. The crux of effective…

Image and Video Processing · Electrical Eng. & Systems 2024-11-08 Salma Hassan , Dawlat Akaila , Maryam Arjemandi , Vijay Papineni , Mohammad Yaqub

Automatic segmentation in MR brain images is important for quantitative analysis in large-scale studies with images acquired at all ages. This paper presents a method for the automatic segmentation of MR brain images into a number of tissue…

Computer Vision and Pattern Recognition · Computer Science 2017-04-12 Pim Moeskops , Max A. Viergever , Adriënne M. Mendrik , Linda S. de Vries , Manon J. N. L. Benders , Ivana Išgum

The diagnosis and segmentation of tumors using any medical diagnostic tool can be challenging due to the varying nature of this pathology. Magnetic Reso- nance Imaging (MRI) is an established diagnostic tool for various diseases and…

Computer Vision and Pattern Recognition · Computer Science 2017-11-01 Tanvi Gupta , Pranay Manocha , Tapan K. Gandhi , RK Gupta , BK Panigrahi

In this paper, we present a Mirroring Neural Network architecture to perform non-linear dimensionality reduction and Object Recognition using a reduced lowdimensional characteristic vector. In addition to dimensionality reduction, the…

Computer Vision and Pattern Recognition · Computer Science 2008-12-13 Dasika Ratna Deepthi , Sujeet Kuchibhotla , K. Eswaran

Dementia of Alzheimer's Type (DAT) is a complex disorder influenced by numerous factors, but it is unclear how each factor contributes to disease progression. An in-depth examination of these factors may yield an accurate estimate of…

Computer-aided early diagnosis of Alzheimer's disease (AD) and its prodromal form mild cognitive impairment (MCI) based on structure Magnetic Resonance Imaging (sMRI) has provided a cost-effective and objective way for early prevention and…

Image and Video Processing · Electrical Eng. & Systems 2021-11-16 Xin Zhang , Liangxiu Han , Wenyong Zhu , Liang Sun , Daoqiang Zhang