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Triangular lattice models for pattern formation by hard-core soft-shell particles at interfaces are introduced and studied in order to determine the effect of the shell thickness and structure. In model I, we consider particles with…

Soft Condensed Matter · Physics 2020-08-26 V. S. Grishina , V. S. Vikhrenko , A. Ciach

We study the stability and shapes of domains with spontaneous curvature in fluid films and membranes, embedded in a surrounding membrane with zero spontaneous curvature. These domains can result from the inclusion of an impurity in a fluid…

Soft Condensed Matter · Physics 2009-11-11 James L. Harden , Fred C. MacKintosh , Peter D. Olmsted

We construct a coarse-grained (CG) model for dipalmitoylphosphatidylcholine (DPPC)/cholesterol bilayers and apply it to large-scale simulation studies of lipid membranes. Our CG model is a two-dimensional representation of the membrane,…

Soft Condensed Matter · Physics 2009-11-10 Teemu Murtola , Emma Falck , Michael Patra , Mikko Karttunen , Ilpo Vattulainen

Molecular dynamics simulations are used to study structure formation in simple model polymer chains that are subject to excluded volume and torsional interactions. The changing conformations exhibited by chains of different lengths under…

Soft Condensed Matter · Physics 2009-11-07 D. C. Rapaport

Multivalent interactions between deformable mesoscopic units are ubiquitous in biology, where membrane macromolecules mediate the interactions between neighbouring living cells and between cells and solid substrates. Lately, analogous…

Biological Physics · Physics 2015-04-20 S. F. Shimobayashi , B. M. Mognetti , L. Parolini , D. Orsi , P. Cicuta , L. Di Michele

A new discrete cohesive zone model (DCZM) is presented for modeling the interface behavior of adhesive-bonded thin laminates and sandwich panels. The proposed model treats the interface as a spring element and the adherent as a beam…

Computational Physics · Physics 2024-10-04 Himanshu , Ananth Ramaswamy

Lipid monolayers and bilayers have been used as experimental models for the investigation of membrane thermal transitions. The main transition takes place near ambient temperatures for several lipids and reflects the order-disorder…

Biological Physics · Physics 2015-06-17 Henrique S. Guidi , Vera B. Henriques

We investigate the behavior of colloidal suspensions with different volume fractions confined between parallel walls under a range of steady shears. We model the particles using molecular dynamics (MD) with full hydrodynamic interactions…

Soft Condensed Matter · Physics 2014-09-18 Frances E. Mackay , Kyle Pastor , Mikko Karttunen , Colin Denniston

We study a model of phantom tethered membranes, embedded in three-dimensional space, by extensive Monte Carlo simulations. The membranes have hexagonal lattice structure where each monomer is interacting with six nearest-neighbors (NN).…

Statistical Mechanics · Physics 2009-11-07 J-P. Kownacki , H. T. Diep

We present a simple and computationally efficient coarse-grained and solvent-free model for simulating lipid bilayer membranes. In order to be used in concert with particle-based reaction-diffusion simulations, the model is purely based on…

Biological Physics · Physics 2018-01-31 Mohsen Sadeghi , Thomas R. Weikl , Frank Noé

Membrane phase-separation is a mechanism that biological membranes often use to locally concentrate specific lipid species in order to organize diverse membrane processes. Phase separation has also been explored as a tool for the design of…

Computational Physics · Physics 2020-06-26 Alexander Zhiliakov , Yifei Wang , Annalisa Quaini , Maxim Olshanskii , Sheereen Majd

We present a model for the efficient simulation of generic bilayer membranes. Individual lipids are represented by one head- and two tail-beads. By means of simple pair potentials these robustly self-assemble to a fluid bilayer state over a…

Soft Condensed Matter · Physics 2009-11-11 Ira R. Cooke , Kurt Kremer , Markus Deserno

The adhesion of biomembranes is mediated by the binding of membrane-anchored receptor and ligand proteins. The proteins can only bind if the separation between apposing membranes is sufficiently close to the length of the protein complexes,…

Subcellular Processes · Quantitative Biology 2019-11-22 Thomas R. Weikl , Jinglei Hu , Batuhan Kav , Bartosz Rozycki

We examine the budding of a nanoscale particle through a lipid bilayer using molecular dynamics simulations, free energy calculations, and an elastic theory, with the aim of determining the extent to which equilibrium elasticity theory can…

Subcellular Processes · Quantitative Biology 2012-02-22 Teresa Ruiz-Herrero , Enrique Velasco , Michael F. Hagan

The first-order phase transitions in the lattice model of Janus-like particles confined in slit-like pores are studied. We assume a cubic lattice with molecules that can freely change their orientation on a lattice site. Moreover, the…

Soft Condensed Matter · Physics 2017-02-13 M. Borówko , A. Patrykiejew , W. Rzysko , S. Sokołowski

In order to precisely quantify the fundamental interactions between heterogeneous lipid membranes with coexisting liquid-ordered (Lo) and liquid-disordered (Ld) domains, we performed detailed osmotic stress SAXS experiments by exploiting…

Soft Condensed Matter · Physics 2015-06-24 Benjamin Kollmitzer , Peter Heftberger , Rudolf Podgornik , John F. Nagle , Georg Pabst

We report a numerical evidence of the discontinuous transition of a tethered membrane model which is defined within a framework of the membrane elasticity of Helfrich. Two kinds of phantom tethered membrane models are studied via the…

Statistical Mechanics · Physics 2009-11-10 Hiroshi Koibuchi , Nobuyuki Kusano , Atsusi Nidaira , Komei Suzuki , Mitsuru Yamada

We present a simple, and physically motivated, coarse-grained model of a lipid bilayer, suited for micron scale computer simulations. Each ~25 nm^2 patch of bilayer is represented by a spherical particle. Mimicking forces of hydrophobic…

Soft Condensed Matter · Physics 2015-05-13 Andrea Pasqua , Lutz Maibaum , George Oster , Daniel A. Fletcher , Phillip L. Geissler

We propose a model that accounts for the budding transition of asymmetric two-component lipid domains, where the two monolayers (leaflets) have different average compositions controlled by independent chemical potentials. Assuming a…

Soft Condensed Matter · Physics 2016-09-16 Jean Wolff , Shigeyuki Komura , David Andelman

The structure of membrane-active peptides and their interaction with lipid bilayers can be studied in oriented lipid membranes deposited on solid substrates. Such systems are desirable for a number of surface-sensitive techniques. Here we…

Soft Condensed Matter · Physics 2015-04-10 Chenghao Li , Doru Constantin , Tim Salditt
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