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We present a particle separation mechanism which induces motion of particles of different sizes in opposite directions. The mechanism is based on the combined action of a driving force and an entropic rectification of the Brownian…

Statistical Mechanics · Physics 2012-02-10 D. Reguera , A. Luque , P. S. Burada , G. Schmid , J. M. Rubí , P. Hänggi

Pinched flow fractionation is shown to be an efficient and selective way to quickly separate particles by size in a very polydisperse semi-concentrated suspension. In an effort to optimize the method, we discuss the quantitative influence…

Fluid Dynamics · Physics 2012-04-17 Aparna Srivastav , Thomas Podgorski , Gwennou Coupier

Transport of spherical Brownian particles of finite size possessing radii through narrow channels with varying cross-section area is considered. Applying the so-called Fick-Jacobs approximation, i.e. assuming fast equilibration in…

Mesoscale and Nanoscale Physics · Physics 2015-05-19 Wolfgang Riefler , Gerhard Schmid , P Sekhar Burada , Peter Hanggi

Efficient particle sorting in microfluidic systems is vital for advancements in biomedical diagnostics and industrial applications. This study numerically investigates particle migration and passive sorting in symmetric serpentine…

Fluid Dynamics · Physics 2025-09-16 Sayan Karmakar , Anish Pal , Sourav Sarkar , Achintya Mukhopadhyay

Inertial effects should be considered for micro- and nano-swimmers moving in a low-density medium confined by irregular structures that create entropic barriers, where viscous effects are no longer paramount. Here, we present a separation…

Soft Condensed Matter · Physics 2024-05-03 Narender Khatri

Particle isolation techniques are in the spotlight of many areas of science and engineering. In food industry, a harmful bacterial activity can be prevented with the help of separation schemes. In health care, isolation techniques are used…

Statistical Mechanics · Physics 2021-03-25 Aleksandra Słapik , Jakub Spiechowicz

A prerequisite for isolating diseased cells requires a mechanism for effective mass-based separation. This objective, however, is generally rather challenging because typically no valid correlation exists between the size of the particles…

Statistical Mechanics · Physics 2019-03-27 Aleksandra Słapik , Jerzy Łuczka , Peter Hänggi , Jakub Spiechowicz

Rectification of interacting Brownian particles is investigated in a two-dimensional asymmetric channel in the presence of an external periodic driving force. The periodic driving force can break the thermodynamic equilibrium and induces…

Soft Condensed Matter · Physics 2021-07-19 Narender Khatri , P. S. Burada

An effective approach to isolation of sub-micro sized particles is desired to separate cancer and healthy cells or in therapy of Parkinson's and Alzheimer's disease. However, since bioparticles span a large size range comprising several…

Statistical Mechanics · Physics 2021-03-25 Aleksandra Słapik , Jerzy Łuczka , Jakub Spiechowicz

We present an amelioration of current known algorithms for optimal spectral partitioning problems. The idea is to use the advantage of a representation using density functions while decreasing the computational time. This is done by…

Optimization and Control · Mathematics 2017-05-25 Beniamin Bogosel

We present a mechanism to sort out particles of different masses in an asymmetric channel, where the entropic barriers arise naturally and control the diffusion of these particles. When particles are subjected to an oscillatory force, with…

Soft Condensed Matter · Physics 2021-10-18 Narender Khatri , P. S. Burada

Microscopic particle separation plays vital role in various scientific and industrial domains. In this Letter, we propose a universal non-equilibrium thermodynamic approach, employing the concept of Shortcuts to Isothermality, to realize…

Statistical Mechanics · Physics 2026-05-19 Xiu-Hua Zhao , Z. C. Tu , Yu-Han Ma

Efficiency of a Brownian particle moving along the axis of a three-dimensional asymmetric periodic channel is investigated in the presence of a symmetric unbiased force and a load. Reduction of the spatial dimensionality from two or three…

Statistical Mechanics · Physics 2009-11-13 Bao-quan Ai , Hui-zhang Xie , Liang-gang Liu

The size- and fluorescence-based sorting of micro- and nano-scale particles suspended in fluid presents a significant and important challenge for both sample analysis and for manufacturing of nanoparticle-based products. Here we demonstrate…

Soft Condensed Matter · Physics 2015-02-16 Sukumar Rajauria , Christopher Axline , Claudia Gottstein , Andrew N. Cleland

The transport of independent active Brownian particles within a two-dimensional narrow channel, modeled as an open-wedge, is studied both numerically and theoretically. We show that the active force tends to localize the particles near the…

Statistical Mechanics · Physics 2019-05-01 Lorenzo Caprini , Fabio Cecconi , Umberto Marini Bettolo Marconi

We consider a molecular machine described as a Brownian particle diffusing in a tilted periodic potential. We evaluate the absorbed and released power of the machine as a function of the applied molecular and chemical forces, by using the…

Statistical Mechanics · Physics 2012-03-23 N. Golubeva , A. Imparato , L. Peliti

We analyze the diffusive transport of Brownian particles in narrow channels with periodically varying cross-section. The geometrical confinements lead to entropic barriers, the particle has to overcome in order to proceed in transport…

Statistical Mechanics · Physics 2012-01-06 P. S. Burada , G. Schmid , Y. Li , P. Hanggi

This article presents a physical biology approach to understanding organization and segregation of bacterial chromosomes. The author uses a "piston" analogy for bacterial chromosomes in a cell, which leads to a phase diagram for the…

Subcellular Processes · Quantitative Biology 2010-06-01 Suckjoon Jun

We describe a method to track particles undergoing large displacements. Starting with a list of particle positions sampled at different time points, we assign particle identities by minimizing the sum across all particles of the trace of…

Soft Condensed Matter · Physics 2016-09-02 Rostislav Boltyanskiy , Jason W. Merrill , Eric R. Dufresne

We study the current rectification of particles moving in a pulsating channel under the in uence of an applied force. We have shown the existence of diferent rectification scenarios in which entropic and energetic effects compete. The…

Soft Condensed Matter · Physics 2018-06-13 M. Florencia Carusela , J. Miguel Rubi
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