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Vector quantization (VQ) based ANN indexes, such as Inverted File System (IVF) and Product Quantization (PQ), have been widely applied to embedding based document retrieval thanks to the competitive time and memory efficiency. Originally,…

Information Retrieval · Computer Science 2022-04-29 Shitao Xiao , Zheng Liu , Weihao Han , Jianjin Zhang , Defu Lian , Yeyun Gong , Qi Chen , Fan Yang , Hao Sun , Yingxia Shao , Denvy Deng , Qi Zhang , Xing Xie

Although the expenses associated with DNA sequencing have been rapidly decreasing, the current cost of sequencing information stands at roughly $120/GB, which is dramatically more expensive than reading from existing archival storage…

Discrete Mathematics · Computer Science 2023-11-30 Daniella Bar-Lev , Omer Sabary , Ryan Gabrys , Eitan Yaakobi

Aligning millions of short DNA or RNA reads, of 75 to 250 base pairs each, to a reference genome is a significant computation problem in bioinformatics. We present a flexible and fast FPGA-based short read alignment tool. Our aligner makes…

Genomics · Quantitative Biology 2018-05-02 Nathaniel McVicar , Akina Hoshino , Anna La Torre , Thomas A. Reh , Walter L. Ruzzo , Scott Hauck

Web search and other large-scale web data analytics rely on processing archives of web pages stored in a standardized and efficient format. Since its introduction in 2008, the IIPC's Web ARCive (WARC) format has become the standard format…

Information Retrieval · Computer Science 2021-12-07 Janek Bevendorff , Martin Potthast , Benno Stein

The recent super-exponential growth in the amount of sequencing data generated worldwide has put techniques for compressed storage into the focus. Most available solutions, however, are strictly tied to specific bioinformatics formats,…

Genomics · Quantitative Biology 2021-11-01 Łukasz Roguski , Paolo Ribeca

Genomic data has become increasingly accessible to the general public with the advent of companies offering whole genome sequencing at a relatively low cost. However, their reports are not verifiable due to a lack of crucial details and…

In a private database query scheme (PDQ), a server maintains a database, and users send queries to retrieve records of interest from the server while keeping their queries private. A crucial step in PDQ protocols based on homomorphic…

Cryptography and Security · Computer Science 2024-09-02 Jung Hee Cheon , Keewoo Lee , Jai Hyun Park , Yongdong Yeo

Deoxyribonucleic Acid (DNA), with its high density and long durability, is a promising storage medium for long-term archival storage and has attracted much attention. Several studies have verified the feasibility of using DNA for archival…

Emerging Technologies · Computer Science 2022-09-15 Yixun Wei , Bingzhe Li , David H. C. Du

DNA sequencing is revolutionising the field of medicine. DNA sequencers, the machines which perform DNA sequencing, have evolved from the size of a fridge to that of a mobile phone over the last two decades. The cost of sequencing a human…

Genomics · Quantitative Biology 2021-01-14 Hasindu Gamaarachchi

With the explosive growth of multi-modal information on the Internet, unimodal search cannot satisfy the requirement of Internet applications. Text-image retrieval research is needed to realize high-quality and efficient retrieval between…

Information Retrieval · Computer Science 2024-04-02 Haoyu Liu , Yaoxian Song , Xuwu Wang , Zhu Xiangru , Zhixu Li , Wei Song , Tiefeng Li

Deep neural network powered artificial intelligence has rapidly changed our daily life with various applications. However, as one of the essential steps of deep neural networks, training a heavily weighted network requires a tremendous…

Quantum Physics · Physics 2021-08-23 Samuel A. Stein , Ryan L'Abbate , Wenrui Mu , Yue Liu , Betis Baheri , Ying Mao , Qiang Guan , Ang Li , Bo Fang

Metagenomic studies have increasingly utilized sequencing technologies in order to analyze DNA fragments found in environmental samples.One important step in this analysis is the taxonomic classification of the DNA fragments. Conventional…

Genomics · Quantitative Biology 2020-02-11 Andreas Georgiou , Vincent Fortuin , Harun Mustafa , Gunnar Rätsch

Recent technological advances in Next Generation Sequencing tools have led to increasing speeds of DNA sample collection, preparation, and sequencing. One instrument can produce over 600 Gb of genetic sequence data in a single run. This…

Quantitative Methods · Quantitative Biology 2016-11-18 Stephanie Dodson , Darrell O. Ricke , Jeremy Kepner

Deep Neural Networks (DNNs) typically require massive amount of computation resource in inference tasks for computer vision applications. Quantization can significantly reduce DNN computation and storage by decreasing the bitwidth of…

We consider the problem of producing compact architectures for text classification, such that the full model fits in a limited amount of memory. After considering different solutions inspired by the hashing literature, we propose a method…

Computation and Language · Computer Science 2016-12-19 Armand Joulin , Edouard Grave , Piotr Bojanowski , Matthijs Douze , Hérve Jégou , Tomas Mikolov

Multimodal encoders have pushed the boundaries of visual document retrieval, matching textual query tokens directly to image patches and achieving state-of-the-art performance on public benchmarks. Recent models relying on this paradigm…

Computation and Language · Computer Science 2026-04-08 Omri Uzan , Asaf Yehudai , Roi pony , Eyal Shnarch , Ariel Gera

DNA sequence classification requires not only high predictive accuracy but also the ability to uncover latent site interactions, combinatorial regulation, and epistasis-like higher-order dependencies. Although the standard Transformer…

Machine Learning · Computer Science 2026-03-30 Zhixuan Cao , Yishu Xu , Xuang WU

The recent detection transformer (DETR) has advanced object detection, but its application on resource-constrained devices requires massive computation and memory resources. Quantization stands out as a solution by representing the network…

Computer Vision and Pattern Recognition · Computer Science 2023-04-04 Sheng Xu , Yanjing Li , Mingbao Lin , Peng Gao , Guodong Guo , Jinhu Lu , Baochang Zhang

We provide an overview of current approaches to DNA-based storage system design and accompanying synthesis, sequencing and editing methods. We also introduce and analyze a suite of new constrained coding schemes for both archival and random…

Emerging Technologies · Computer Science 2015-07-08 S. M. Hossein Tabatabaei Yazdi , Han Mao Kiah , Eva Ruiz Garcia , Jian Ma , Huimin Zhao , Olgica Milenkovic

The search for similar genetic sequences is one of the main bioinformatics tasks. The genetic sequences data banks are growing exponentially and the searching techniques that use linear time are not capable to do the search in the required…

Distributed, Parallel, and Cluster Computing · Computer Science 2015-07-13 Felipe Albrecht