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Many ecological questions center on complex phenomena, such as species interactions, behaviors, phenology, and responses to disturbance, that are inherently difficult to observe and sparsely documented. Community science platforms such as…

The unprecedented prowess of measurement techniques provides a detailed, multi-scale look into the depths of living systems. Understanding these avalanches of high-dimensional data -- by distilling underlying principles and mechanisms --…

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Time-series data exists in every corner of real-world systems and services, ranging from satellites in the sky to wearable devices on human bodies. Learning representations by extracting and inferring valuable information from these time…

Machine Learning · Computer Science 2026-05-19 Patara Trirat , Yooju Shin , Junhyeok Kang , Youngeun Nam , Jihye Na , Minyoung Bae , Joeun Kim , Byunghyun Kim , Jae-Gil Lee

Sample-efficient exploration is crucial not only for discovering rewarding experiences but also for adapting to environment changes in a task-agnostic fashion. A principled treatment of the problem of optimal input synthesis for system…

Machine Learning · Computer Science 2019-10-10 Matthias Schultheis , Boris Belousov , Hany Abdulsamad , Jan Peters

The rapid evolution of scientific fields introduces challenges in organizing and retrieving scientific literature. While expert-curated taxonomies have traditionally addressed this need, the process is time-consuming and expensive.…

Computation and Language · Computer Science 2025-06-13 Priyanka Kargupta , Nan Zhang , Yunyi Zhang , Rui Zhang , Prasenjit Mitra , Jiawei Han

Understanding the future climate is crucial for informed policy decisions on climate change prevention and mitigation. Earth system models play an important role in predicting future climate, requiring accurate representation of complex…

Machine Learning · Computer Science 2024-01-09 Christian Reimers , David Hafezi Rachti , Guahua Liu , Alexander J. Winkler

The development of multicellular organisms entails a deep connection between time-dependent biochemical processes taking place at the subcellular level, and the resulting macroscopic phenotypes that arise in populations of up to trillions…

Biological Physics · Physics 2025-10-07 Ben Ansbacher , Malachy Guzman , Jordi Garcia-Ojalvo , Arjendu K Pattanayak

Emerging data analysis involves the ingestion and exploration of new data sets, application of complex functions, and frequent query revisions based on observing prior query answers. We call this new type of analysis evolutionary analytics…

Databases · Computer Science 2013-06-28 Jeff LeFevre , Jagan Sankaranarayanan , Hakan Hacigumus , Junichi Tatemura , Neoklis Polyzotis

In the past few decades, the life sciences have experienced an unprecedented accumulation of data, ranging from genomic sequences and proteomic profiles to heavy-content imaging, clinical assays, and commercial biological products for…

Databases · Computer Science 2025-09-22 Rosalia Moreddu

We propose a generic model of eco-systems, with a {\it hierarchical} food web structure. In our computer simulations we let the eco-system evolve continuously for so long that that we can monitor extinctions as well as speciations over…

Populations and Evolution · Quantitative Biology 2009-11-10 Debashish Chowdhury , Dietrich Stauffer

Ancestral sequence reconstruction is a key task in computational biology. It consists in inferring a molecular sequence at an ancestral species of a known phylogeny, given descendant sequences at the tip of the tree. In addition to its many…

Populations and Evolution · Quantitative Biology 2022-07-27 Brandon Legried , Sebastien Roch

Differential Evolution (DE) is a renowned optimization stratagem that can easily solve nonlinear and comprehensive problems. DE is a well known and uncomplicated population based probabilistic approach for comprehensive optimization. It has…

Neural and Evolutionary Computing · Computer Science 2015-06-22 Sandeep Kumar , Vivek Kumar Sharma , Rajani Kumari

Recent technological advances and long-term data studies provide interaction data that can be modelled through dynamic networks, i.e a sequence of different snapshots of an evolving ecological network. Most often time is the parameter along…

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E. coli chemotactic motion in the presence of a chemoattractant field has been extensively studied using wet laboratory experiments, stochastic computational models as well as partial differential equation-based models (PDEs). The most…

Quantitative Methods · Quantitative Biology 2022-08-26 Yorgos M. Psarellis , Seungjoon Lee , Tapomoy Bhattacharjee , Sujit S. Datta , Juan M. Bello-Rivas , Ioannis G. Kevrekidis

Astronomy is undergoing through a methodological revolution triggered by an unprecedented wealth of complex and accurate data. The new panchromatic, synoptic sky surveys require advanced tools for discovering patterns and trends hidden…

Here we introduce a new design framework for synthetic biology that exploits the advantages of Bayesian model selection. We will argue that the difference between inference and design is that in the former we try to reconstruct the system…

Molecular Networks · Quantitative Biology 2015-05-27 Chris Barnes , Daniel Silk , Xia Sheng , Michael P. H. Stumpf

This article presents GenSQL, a probabilistic programming system for querying probabilistic generative models of database tables. By augmenting SQL with only a few key primitives for querying probabilistic models, GenSQL enables complex…

Dynamic Bayesian networks (DBNs) offer an elegant way to integrate various aspects of language in one model. Many existing algorithms developed for learning and inference in DBNs are applicable to probabilistic language modeling. To…

Computation and Language · Computer Science 2007-05-23 Leonid Peshkin , Avi Pfeffer

Predicting the dynamics of complex systems is crucial for various scientific and engineering applications. The accuracy of predictions depends on the model's ability to capture the intrinsic dynamics. While existing methods capture key…

Computational Engineering, Finance, and Science · Computer Science 2025-06-10 Ruikun Li , Jingwen Cheng , Huandong Wang , Qingmin Liao , Yong Li

Time-delayed differential equations (TDDEs) are widely used to model complex dynamic systems where future states depend on past states with a delay. However, inferring the underlying TDDEs from observed data remains a challenging problem…

Machine Learning · Statistics 2025-01-07 Debangshu Chowdhury , Souvik Chakraborty