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Lymph node (LN) assessment is a critical, indispensable yet very challenging task in the routine clinical workflow of radiology and oncology. Accurate LN analysis is essential for cancer diagnosis, staging, and treatment planning. Finding…

Computer Vision and Pattern Recognition · Computer Science 2025-04-24 Yirui Wang , Qinji Yu , Ke Yan , Haoshen Li , Dazhou Guo , Li Zhang , Le Lu , Na Shen , Qifeng Wang , Xiaowei Ding , Xianghua Ye , Dakai Jin

Enlarged lymph nodes (LNs) can provide important information for cancer diagnosis, staging, and measuring treatment reactions, making automated detection a highly sought goal. In this paper, we propose a new algorithm representation of…

Computer Vision and Pattern Recognition · Computer Science 2014-08-15 Ari Seff , Le Lu , Kevin M. Cherry , Holger Roth , Jiamin Liu , Shijun Wang , Joanne Hoffman , Evrim B. Turkbey , Ronald M. Summers

Automatic lymph node (LN) segmentation and detection for cancer staging are critical. In clinical practice, computed tomography (CT) and positron emission tomography (PET) imaging detect abnormal LNs. Despite its low contrast and variety in…

Image and Video Processing · Electrical Eng. & Systems 2022-12-23 Al-Akhir Nayan , Boonserm Kijsirikul , Yuji Iwahori

Purpose: Lymph nodes (LNs) in the chest have a tendency to enlarge due to various pathologies, such as lung cancer or pneumonia. Clinicians routinely measure nodal size to monitor disease progression, confirm metastatic cancer, and assess…

Image and Video Processing · Electrical Eng. & Systems 2024-01-15 Tejas Sudharshan Mathai , Bohan Liu , Ronald M. Summers

Purpose: Identification of abdominal Lymph Nodes (LN) that are suspicious for metastasis in T2 Magnetic Resonance Imaging (MRI) scans is critical for staging of lymphoproliferative diseases. Prior work on LN detection has been limited to…

Image and Video Processing · Electrical Eng. & Systems 2022-04-05 Tejas Sudharshan Mathai , Sungwon Lee , Thomas C. Shen , Zhiyong Lu , Ronald M. Summers

As lung cancer evolves, the presence of enlarged and potentially malignant lymph nodes must be assessed to properly estimate disease progression and select the best treatment strategy. Following the clinical guidelines, estimation of…

Image and Video Processing · Electrical Eng. & Systems 2022-05-03 David Bouget , André Pedersen , Johanna Vanel , Haakon O. Leira , Thomas Langø

Lymph node (LN) assessment is an essential task in the routine radiology workflow, providing valuable insights for cancer staging, treatment planning and beyond. Identifying scatteredly-distributed and low-contrast LNs in 3D CT scans is…

Computer Vision and Pattern Recognition · Computer Science 2025-03-14 Qinji Yu , Yirui Wang , Ke Yan , Dandan Zheng , Dashan Ai , Dazhou Guo , Zhanghexuan Ji , Yanzhou Su , Yun Bian , Na Shen , Xiaowei Ding , Le Lu , Xianghua Ye , Dakai Jin

Early detection of lung cancer is crucial for effective treatment and relies on accurate volumetric assessment of pulmonary nodules in CT scans. Traditional methods, such as consolidation-to-tumor ratio (CTR) and spherical approximation,…

Image and Video Processing · Electrical Eng. & Systems 2025-08-29 Yihan Zhou , Haocheng Huang , Yue Yu , Jianhui Shang

Robust localization of lymph nodes (LNs) in multiparametric MRI (mpMRI) is critical for the assessment of lymphadenopathy. Radiologists routinely measure the size of LN to distinguish benign from malignant nodes, which would require…

Image and Video Processing · Electrical Eng. & Systems 2025-04-08 Tejas Sudharshan Mathai , Sungwon Lee , Thomas C. Shen , Zhiyong Lu , Ronald M. Summers

Lymph node station (LNS) delineation from computed tomography (CT) scans is an indispensable step in radiation oncology workflow. High inter-user variabilities across oncologists and prohibitive laboring costs motivated the automated…

Image and Video Processing · Electrical Eng. & Systems 2021-09-21 Dazhou Guo , Xianghua Ye , Jia Ge , Xing Di , Le Lu , Lingyun Huang , Guotong Xie , Jing Xiao , Zhongjie Liu , Ling Peng , Senxiang Yan , Dakai Jin

Lymph node metastasis (LNM) is a significant prognostic factor in patients with head and neck cancer, and the ability to predict it accurately is essential for treatment optimization. PET and CT imaging are routinely used for LNM…

Finding abnormal lymph nodes in radiological images is highly important for various medical tasks such as cancer metastasis staging and radiotherapy planning. Lymph nodes (LNs) are small glands scattered throughout the body. They are…

Computer Vision and Pattern Recognition · Computer Science 2023-07-31 Ke Yan , Dakai Jin , Dazhou Guo , Minfeng Xu , Na Shen , Xian-Sheng Hua , Xianghua Ye , Le Lu

Lymph node metastasis (LNM) is a significant prognostic factor in patients with head and neck cancer, and the ability to predict it accurately is essential for treatment optimization. PET and CT imaging are routinely used for LNM…

Effective treatment for rectal cancer relies on accurate lymph node metastasis (LNM) staging. However, radiological criteria based on lymph node (LN) size, shape and texture morphology have limited diagnostic accuracy. In this work, we…

Computer Vision and Pattern Recognition · Computer Science 2025-07-17 Benjamin Keel , Aaron Quyn , David Jayne , Maryam Mohsin , Samuel D. Relton

Automated computer-aided detection (CADe) in medical imaging has been an important tool in clinical practice and research. State-of-the-art methods often show high sensitivities but at the cost of high false-positives (FP) per patient…

Computer Vision and Pattern Recognition · Computer Science 2016-04-26 Holger R. Roth , Le Lu , Jiamin Liu , Jianhua Yao , Ari Seff , Kevin Cherry , Lauren Kim , Ronald M. Summers

Early detection of pulmonary nodules in computed tomography (CT) images is essential for successful outcomes among lung cancer patients. Much attention has been given to deep convolutional neural network (DCNN)-based approaches to this…

Computer Vision and Pattern Recognition · Computer Science 2019-03-26 Hao Tang , Daniel R. Kim , Xiaohui Xie

Objective: In clinical practice, small lung nodules can be easily overlooked by radiologists. The paper aims to provide an efficient and accurate detection system for small lung nodules while keeping good performance for large nodules.…

Image and Video Processing · Electrical Eng. & Systems 2021-06-09 Sunyi Zheng , Ludo J. Cornelissen , Xiaonan Cui , Xueping Jing , Raymond N. J. Veldhuis , Matthijs Oudkerk , Peter M. A. van Ooijen

Purpose Segmentation of the liver from abdominal computed tomography (CT) image is an essential step in some computer assisted clinical interventions, such as surgery planning for living donor liver transplant (LDLT), radiotherapy and…

Computer Vision and Pattern Recognition · Computer Science 2016-05-11 Fang Lu , Fa Wu , Peijun Hu , Zhiyi Peng , Dexing Kong

Radiation therapy (RT) is widely employed in the clinic for the treatment of head and neck (HaN) cancers. An essential step of RT planning is the accurate segmentation of various organs-at-risks (OARs) in HaN CT images. Nevertheless,…

Image and Video Processing · Electrical Eng. & Systems 2021-09-28 Zijie Chen , Cheng Li , Junjun He , Jin Ye , Diping Song , Shanshan Wang , Lixu Gu , Yu Qiao

Determining the spread of GTV$_{LN}$ is essential in defining the respective resection or irradiating regions for the downstream workflows of surgical resection and radiotherapy for many cancers. Different from the more common enlarged…

Computer Vision and Pattern Recognition · Computer Science 2020-09-01 Chun-Hung Chao , Zhuotun Zhu , Dazhou Guo , Ke Yan , Tsung-Ying Ho , Jinzheng Cai , Adam P. Harrison , Xianghua Ye , Jing Xiao , Alan Yuille , Min Sun , Le Lu , Dakai Jin
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