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Many cells face search problems, such as finding food, mates or shelter, where their success depends on their search strategy. In contrast to other unicellular organisms, the slime mold Physarum polycephalum forms a giant network-shaped…

Biological Physics · Physics 2024-09-20 Lucas Tröger , Florian Goirand , Karen Alim

P. polycephalum may be considered as a spatially represented parallel unconventional computing substrate, but how can this `computer' be programmed? In this paper we examine and catalogue individual low-level mechanisms which may be used to…

Emerging Technologies · Computer Science 2016-10-23 Jeff Jones

Plasmodium of Physarum polycephalum is a single cell visible by unaided eye. During its foraging behavior the cell spans spatially distributed sources of nutrients with a protoplasmic network. Geometrical structure of the protoplasmic…

Pattern Formation and Solitons · Physics 2015-03-17 Andrew Adamatzky , Genaro J. Martinez , Sergio V. Chapa-Vergara , Rene Asomoza-Palacio , Christopher R. Stephens

Plasmodium of Physarum polycephalum is a large cell capable of solving graph-theoretic, optimization and computational geometry problems due to its unique foraging behavior. Also the plasmodium is unique biological substrate that mimics…

Adaptation and Self-Organizing Systems · Physics 2010-11-23 Andrew Adamatzky , Jeff Jones

Physarum polycephalum is a single-celled, multi-nucleated slime mold whose body constitutes a network of veins. As it explores its environment, it adapts and optimizes its network to external stimuli. It has been shown to exhibit complex…

Fluid Dynamics · Physics 2023-09-20 Ana Filipa Valente

Plasmodium of Physarum polycephalum is a single cell visible by unaided eye. During its foraging behaviour the cell spans spatially distributed sources of nutrients with a protoplasmic network. Geometrical structure of the protoplasmic…

Pattern Formation and Solitons · Physics 2015-05-14 Andrew Adamatzky , Jeff Jones

A fundamental question regarding biological transport networks is the interplay between the network development or reorganization and the flows it carries. We use Physarum polycephalum, a true slime mould with a transport network which…

Biological Physics · Physics 2022-12-27 Raphaël Saiseau , Valentin Busson , Laura Xénard , Marc Durand

We propose a novel model of unconventional computing where a structural part of computation is presented by dynamics of plasmodium of Physarum polycephalum, a large single cell. We sketch a new logical approach combining conventional logic…

Logic in Computer Science · Computer Science 2011-05-23 Andrew Schumann , Andrew Adamatzky

A plasmodium of Physarum polycephalum is a very large cell visible by unaided eye. The plasmodium is capable for distributed sensing, parallel information processing, and decentralized optimization. It is an ideal substrate for future and…

Pattern Formation and Solitons · Physics 2012-08-14 Andrew Adamatzky

Belgium is amongst few artificial countries, established on purpose, when Dutch and French speaking parts were joined in a single unit. This makes Belgium a particularly interesting testbed for studying bio-inspired techniques for…

Adaptation and Self-Organizing Systems · Physics 2011-12-21 Andrew Adamatzky , Bernard De Baets , Wesley Van Dessel

The plasmodium of Physarum polycephalum is renowned for spanning sources of nutrients with networks of protoplasmic tubes. The networks transport nutrients and metabolites across the plasmodium's body. To imitate a hypothetical colonisation…

Adaptation and Self-Organizing Systems · Physics 2012-09-19 Andrew Adamatzky

In laboratory experiments we demonstrate that protoplasmic tubes of acellular slime mould \emph{Physarum polycephalum} show current versus voltage profiles consistent with memristive systems and that the effect is due to the living…

Emerging Technologies · Computer Science 2014-11-25 Ella Gale , Andrew Adamatzky , Ben de Lacy Costello

Slime mould Physarum polycephalum builds up sophisticated networks to transport nutrients between distant part of its extended body. The slime mould's protoplasmic network is optimised for maximum coverage of nutrients yet minimum energy…

Pattern Formation and Solitons · Physics 2015-03-19 Andrew Adamatzky , Selim G. Akl

Coordination of cytoplasmic flows on large scales in space and time are at the root of many cellular processes, including growth, migration or division. These flows are driven by organized contractions of the actomyosin cortex. In order to…

Adaptation and Self-Organizing Systems · Physics 2022-07-29 Busson Valentin , Saiseau Raphaël , Durand Marc

The Physarum network expands or retracts in response to environmental stimuli, demonstrating an intelligent adaptive capability to locate optimal paths for nutrient transport. The underlying physical mechanism governing this intelligence…

Biological Physics · Physics 2026-02-03 Bingyang Han , Luolan Chen , Tieyan Si

This paper introduces Polyphorm, an interactive visualization and model fitting tool that provides a novel approach for investigating cosmological datasets. Through a fast computational simulation method inspired by the behavior of Physarum…

Instrumentation and Methods for Astrophysics · Physics 2020-09-08 Oskar Elek , Joseph N. Burchett , J. Xavier Prochaska , Angus G. Forbes

We investigate flow-driven amoeboid motility as exhibited by microplasmodia of Physarum polycephalum. A poroelastic two-phase model with rigid boundaries is extended to the case of free boundaries and substrate friction. The cytoskeleton is…

Soft Condensed Matter · Physics 2018-11-14 Dirk Alexander Kulawiak , Jakob Löber , Markus Bär , Harald Engel

Lateral Inhibition (LI) phenomena occur in a wide range of sensory modalities and are most famously described in the human visual system. In LI the activity of a stimulated neuron is itself excited and suppresses the activity of its local…

Emerging Technologies · Computer Science 2015-11-25 Jeff Dale Jones

Acellular slime mould Physarum polycephalum is a monstrously large single cell visible by an unaided eye. It shows sophisticated behavioural traits in foraging for nutrients and developing an optimal transport network of protoplasmic tubes…

Pattern Formation and Solitons · Physics 2013-05-17 Andrew Adamatzky

Wounding is a severe impairment of function, especially for an exposed organism like the network-forming true slime mould Physarum polycephalum. The tubular network making up the organism's body plan is entirely interconnected and shares a…

Quantitative Methods · Quantitative Biology 2017-10-25 Felix Bäuerle , Mirna Kramar , Karen Alim