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Spatial light modulators are widely used to perform modulations of different properties of the electromagnetic field. In this work, a simple optimization method for general double-pass setups was developed. It takes into account the…

Optics · Physics 2022-02-09 Sebastián Bordakevich , Lorena Rebón , Silvia Ledesma

Many emerging reconfigurable optical systems are limited by routing complexity when producing dynamic, two-dimensional (2D) electric fields. Using a gradient-based inverse designed, static phase-mask doublet, we propose an optical system to…

Multifocal microscopy (MFM) offers high-speed three-dimensional imaging through the simultaneous image capture from multiple focal planes. Conventional MFM systems use a fabricated grating in the emission path for a single emission…

Biological Physics · Physics 2019-07-31 M. Junaid Amin , Sabine Petry , Haw Yang , Joshua W. Shaevitz

The evolution of X-ray detection technology has significantly enhanced sensitivity and spatial resolution in non-destructive imaging of internal structure. However, the problem of low luminescence and transparency of scintillator materials…

Optics · Physics 2025-07-16 Tatsunori Shibuya , Eichi Terasawa , Hiromi Kimura , Takeshi Fujiwara

Structured illumination microscopy (SIM) achieves superresolution in fluorescence imaging through patterned illumination and computational image reconstruction, yet current methods require bulky, costly modulation optics and high-precision…

Optics · Physics 2024-04-15 Tamal Roy , Peter T. Brown , Douglas P. Shepherd , Lisa V. Poulikakos

Fourier ptychographic (FP) microscope is a coherent imaging method that can synthesize an image with a higher bandwidth using multiple low-bandwidth images captured at different spatial frequency regions. The method's demand for multiple…

Optics · Physics 2016-03-25 Jaebum Chung , Hangwen Lu , Xiaoze Ou , Haojiang Zhou , Changhuei Yang

A resolution-enhanced dark-field microscope by structured light illumination is proposed to improve resolution and contrast. A set of phase-shifted fringes are projected to the sample plane at large angle to capture modulated dark-field…

Image and Video Processing · Electrical Eng. & Systems 2022-02-14 Shaobai Li , Bofan Song , Rongguang Liang

Intensity modulators are an essential component in optics for controlling free-space beams. Many applications require the intensity of a free-space beam to be modulated at a single frequency, including wide-field lock-in detection for…

We report a novel extension to structured illumination (SI) microscopy that utilizes the Talbot self-imaging effect to generate a SI pattern on a sample with field-of-view (FOV) and resolution unconstrained by the numerical aperture (NA) of…

Optics · Physics 2018-01-12 Shwetadwip Chowdhury , Jeffrey Chen , Joseph A. Izatt

Single-beam super-resolution microscopy, also known as superlinear microscopy, exploits the nonlinear response of fluorescent probes in confocal microscopy. The technique requires no complex purpose-built system, light field modulation, or…

We demonstrate a reconfigurable optical filter implemented using a phase-only two-dimensional liquid crystal on silicon spatial light modulator. To achieve this we utilize two different approaches leading to two different configurations in…

By integrating a phase-only Spatial Light Modulator (SLM) into the illumination arm of a cylindrical-lens-based Selective Plane Illumination Microscope (SPIM), we have created a versatile system able to deliver high quality images by…

Biological Physics · Physics 2018-08-10 Chiara Garbellotto , Jonathan M. Taylor

We present a novel, interferometric, two-color, high-order harmonic generation setup, based on a turn-key Ytterbium-doped femtosecond laser source and its second harmonic. Each interferometer arm contains a spatial light modulator, with…

Structured illumination microscopy (SIM) is an important super-resolution based microscopy technique that breaks the diffraction limit and enhances optical microscopy systems. With the development of biology and medical engineering, there…

Image and Video Processing · Electrical Eng. & Systems 2021-11-18 Xi Cheng , Jun Li , Qiang Dai , Zhenyong Fu , Jian Yang

Fast, reprogrammable control over the transverse structure of light beams plays an essential role in applications such as structured illumination microscopy, optical trapping, and quantum information processing. Existing technologies, such…

Reconfigurable photonic devices capable of routing the flow of light enable flexible integrated-optic circuits that are not hard-wired but can be externally controlled. Analogous to free-space spatial light modulators, we demonstrate…

We present a technique for rapid site-selective control of the quantum state of particles in a large array using a combination of a fast deflector (e.g. an acousto-optic deflector) and a relatively slow spatial light modulator. The use of…

Quantum Physics · Physics 2023-05-03 T. M. Graham , E. Oh , M. Saffman

Wide-field fluorescence microscopy, while much faster than confocal microscopy, suffers from a lack of optical sectioning and poor axial resolution. 3D structured illumination microscopy (SIM) has been demonstrated to provide optical…

Structured illumination in Single Molecule Localization Microscopy provides new information on the position of molecules and thus improves the localization precision compared to standard localization methods. Here, we used a time-shifted…

Spatial light modulators (SLMs) are central to numerous applications ranging from high-speed displays to adaptive optics, structured illumination microscopy, and holography. After decades of advances, SLM arrays based on liquid crystals can…

Optics · Physics 2019-10-23 Cheng Peng , Ryan Hamerly , Mohammad Soltani , Dirk Englund