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We present a message-passing algorithm to solve the edge disjoint path problem (EDP) on graphs incorporating under a unique framework both traffic optimization and path length minimization. The min-sum equations for this problem present an…

Disordered Systems and Neural Networks · Physics 2016-01-21 Fabrizio Altarelli , Alfredo Braunstein , Luca Dall'Asta , Caterina De Bacco , Silvio Franz

We present an efficient algorithm for calculating the minimum energy path (MEP) and energy barriers between local minima on a multidimensional potential energy surface (PES). Such paths play a central role in the understanding of transition…

Computational Physics · Physics 2012-04-19 Amit Samanta , Weinan E

Global optimization of transition paths in complex atomic scale systems is addressed in the context of misfit dislocation formation in a strained Ge film on Si(001). Such paths contain multiple intermediate minima connected by minimum…

Materials Science · Physics 2016-06-22 Emile Maras , Oleg Trushin , Alexander Stukowski , Tapio Ala-Nissila , Hannes Jonsson

Path optimization methods have been widely used and highly successful for the analysis of chemical reactions. Yet, they can fail to capture intrinsically multidimensional features of potential energy surfaces (PES). We introduce the nudged…

Statistical Mechanics · Physics 2026-04-23 Uday Sankar Manoj , Nicole Drew , Ismaila Dabo , Lukas Muechler

This paper presents a simple approach to low-thrust optimal-fuel and optimal-time transfer problems between two elliptic orbits using the Cartesian coordinates system. In this case, an orbit is described by its specific angular momentum and…

Optimization and Control · Mathematics 2014-12-09 Hantian Zhang , Dong Eui Chang , Qingjie Cao

We show that neural networks can be optimized to represent minimum energy paths as continuous functions, offering a flexible alternative to discrete path-search methods such as Nudged Elastic Band (NEB). Our approach parameterizes reaction…

Machine Learning · Computer Science 2025-07-10 Kalyan Ramakrishnan , Lars L. Schaaf , Chen Lin , Guangrun Wang , Philip Torr

Efficient and reliable identification and optimization of transition state structures is a longstanding challenge in computational chemistry. Popular chain-of-states methods require hundreds if not thousands of ab initio calculations to…

Chemical Physics · Physics 2025-11-27 Diptarka Hait , Jan D. Estrada Pabón , Martin Stöhr , Todd J. Martínez

Characterizing conformational transitions in physical systems remains a fundamental challenge, as traditional sampling methods struggle with the high-dimensional nature of molecular systems and high-energy barriers between stable states.…

Chemical Physics · Physics 2025-09-22 Magnus Petersen , Gemma Roig , Roberto Covino

Intramolecular symmetry-adapted perturbation theory (ISAPT) is a method to compute and decompose the noncovalent interaction energy between two molecular fragments A and B connected via a linker C. The existing ISAPT algorithm displays…

Chemical Physics · Physics 2022-09-13 Du Luu , Konrad Patkowski

We introduce Parametric Density Path Optimization (PDPO), a novel method for computing action-minimizing paths between probability densities. The core idea is to represent the target probability path as the pushforward of a reference…

Optimization and Control · Mathematics 2025-12-08 Sebastian Gutierrez Hernandez , Peng Chen , Haomin Zhou

Iron phosphate glasses (IPG) have been proposed as futuristic glass material for nuclear waste immobilization, anode material for lithium batteries and also as bioactive glass. In the last decade, there have been attempts to propose…

Materials Science · Physics 2025-04-28 Shakti Singh , Manan Dholakia , Sharat Chandra

This paper addresses local path re-planning for $n$-dimensional systems by introducing an informed sampling scheme and cost function to achieve collision avoidance with minimum deviation from an (optimal) nominal path. The proposed informed…

Robotics · Computer Science 2023-01-04 Thomas T. Enevoldsen , Roberto Galeazzi

Recently, sophisticated deep learning-based approaches have been developed for generating efficient initial guesses to accelerate the convergence of density functional theory (DFT) calculations. While the actual initial guesses are often…

Chemical Physics · Physics 2026-03-24 Zhe Liu , Yuyan Ni , Zhichen Pu , Qiming Sun , Siyuan Liu , Wen Yan

The performance of time-independent, orbital optimized calculations of excited states is assessed with respect to charge transfer excitations in organic molecules in comparison to the linear-response time-dependent density functional theory…

Chemical Physics · Physics 2024-05-22 Elli Selenius , Alec Elías Sigurdarson , Yorick L. A. Schmerwitz , Gianluca Levi

The minimum energy path (MEP) is the most probable transition path that connects two equilibrium states of a potential energy landscape. It has been widely used to study transition mechanisms as well as transition rates in the fields of…

Numerical Analysis · Mathematics 2022-07-01 Xuanyu Liu , Huajie Chen , Christoph Ortner

We describe a robust and efficient chain-of-states method for computing Minimum Energy Paths~(MEPs) associated to barrier-crossing events in poly-atomic systems. The path is parametrized in terms of a continuous variable $t \in [0,1]$ that…

Chemical Physics · Physics 2015-10-26 E. R. Hernandez , C. P. Herrero , J. M. Soler

The convergence of self-consistent field equations in mean-field nuclear-electronic orbital methods strongly depends on the choice of initial guesses for quantum nuclei. Although several such guesses have been proposed in the literature, a…

Chemical Physics · Physics 2026-02-18 Denis G. Artiukhin

This paper proposes a learning-based approach to accelerate the interior-point method (IPM) for solving optimal power flow (OPF) problems by learning the structure of the IPM central path from its early stable iterations. Unlike traditional…

Systems and Control · Electrical Eng. & Systems 2026-03-05 Farshad Amani , Amin Kargarian , Ramachandran Vaidyanathan

Given a multidimensional free-energy or potential-energy landscape, finding reaction paths that connect an initial (or reactant) state and a final (or product) state is important for biophysics and materials science. The likelihood of a…

Statistical Mechanics · Physics 2024-12-12 Tetsuro Nagai , Koji Yoshida

The discovery of a minimum energy pathway (MEP) between metastable states is crucial for scientific tasks including catalyst and biomolecular design. However, the standard nudged elastic band (NEB) algorithm requires hundreds to tens of…

Materials Science · Physics 2025-12-18 Pranav Kakhandiki , Sathya Chitturi , Daniel Ratner , Sean Gasiorowski