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We study possible applications of artificial neural networks to examine the string landscape. Since the field of application is rather versatile, we propose to dynamically evolve these networks via genetic algorithms. This means that we…

High Energy Physics - Theory · Physics 2017-09-13 Fabian Ruehle

We survey the different methods used for extending the BWT to collections of strings, following largely [Cenzato and Lipt\'ak, CPM 2022, Bioinformatics 2024]. We analyze the specific aspects and combinatorial properties of the resulting BWT…

Data Structures and Algorithms · Computer Science 2025-06-03 Davide Cenzato , Zsuzsanna Lipták , Nadia Pisanti , Giovanna Rosone , Marinella Sciortino

The de Bruijn graph $G_K$ of a set of strings $S$ is a key data structure in genome assembly that represents overlaps between all the $K$-length substrings of $S$. Construction and navigation of the graph is a space and time bottleneck in…

Data Structures and Algorithms · Computer Science 2014-11-18 Christina Boucher , Alex Bowe , Travis Gagie , Simon J. Puglisi , Kunihiko Sadakane

Sequence feature embedding is a challenging task due to the unstructuredness of sequence, i.e., arbitrary strings of arbitrary length. Existing methods are efficient in extracting short-term dependencies but typically suffer from…

Machine Learning · Statistics 2021-10-06 Chitta Ranjan , Samaneh Ebrahimi , Kamran Paynabar

Clustering is an unsupervised learning technique in which data or objects are grouped into sets based on some similarity measure. Most of the clustering algorithms assume that the main memory is infinite and can accommodate the set of…

Data Structures and Algorithms · Computer Science 2015-05-25 Pankaj Kumar Yadav , Sriniwas Pandey , Sraban Kumar Mohanty

In this paper, we consider the outer channel for DNA-based data storage. When transmitting over the outer channel, each DNA string is treated as a unit/symbol that would be either correctly received, or erased, or corrupted by uniformly…

Information Theory · Computer Science 2025-09-23 Xuan He , Yi Ding , Kui Cai , Guanghui Song , Bin Dai , Xiaohu Tang

Analyzing interconnection structures among underlying entities or objects in a dataset through the use of graph analytics has been shown to provide tremendous value in many application domains. However, graphs are not the primary…

Databases · Computer Science 2017-02-14 Konstantinos Xirogiannopoulos , Amol Deshpande

We engineer algorithms for sorting huge data sets on massively parallel machines. The algorithms are based on the multiway merging paradigm. We first outline an algorithm whose I/O requirement is close to a lower bound. Thus, in contrast to…

Data Structures and Algorithms · Computer Science 2009-10-15 Mirko Rahn , Peter Sanders , Johannes Singler

LFR is a popular benchmark graph generator used to evaluate community detection algorithms. We present EM-LFR, the first external memory algorithm able to generate massive complex networks following the LFR benchmark. Its most expensive…

Data Structures and Algorithms · Computer Science 2017-06-15 Michael Hamann , Ulrich Meyer , Manuel Penschuck , Hung Tran , Dorothea Wagner

Finding Minimal Unsatisfiable Subsets (MUSes) of binary constraints is a common problem in infeasibility analysis of over-constrained systems. However, because of the exponential search space of the problem, enumerating MUSes is extremely…

Artificial Intelligence · Computer Science 2024-02-27 Panagiotis Lymperopoulos , Liping Liu

To understand the structure of a network, it can be useful to break it down into its constituent pieces. This is the approach taken in a multitude of successful network analysis methods, such as motif analysis. These methods require one to…

Physics and Society · Physics 2023-08-02 Tarmo Nurmi , Mikko Kivelä

A string matching -- and more generally, sequence matching -- algorithm is presented that has a linear worst-case computing time bound, a low worst-case bound on the number of comparisons (2n), and sublinear average-case behavior that is…

Data Structures and Algorithms · Computer Science 2008-10-02 David R. Musser , Gor V. Nishanov

String diagrams provide an intuitive language for expressing networks of interacting processes graphically. A discrete representation of string diagrams, called string graphs, allows for mechanised equational reasoning by double-pushout…

Logic in Computer Science · Computer Science 2015-10-14 Aleks Kissinger , Vladimir Zamdzhiev

The reduction of the fragment assembly problem to (variations of) the classical Eulerian trail problem [Pevzner et al., PNAS 2001] has led to remarkable progress in genome assembly. This reduction employs the notion of de Bruijn graph…

Data Structures and Algorithms · Computer Science 2025-10-17 Ben Bals , Sebastiaan van Krieken , Solon P. Pissis , Leen Stougie , Hilde Verbeek

Gene assembly is an intricate biological process that has been studied formally and modeled through string and graph rewriting systems. Recently, a restriction of the general (intramolecular) model, called simple gene assembly, has been…

Logic in Computer Science · Computer Science 2007-12-21 Robert Brijder , Hendrik Jan Hoogeboom

Prediction of protein secondary structure from the amino acid sequence is a classical bioinformatics problem. Common methods use feed forward neural networks or SVMs combined with a sliding window, as these models does not naturally handle…

Quantitative Methods · Quantitative Biology 2015-01-06 Søren Kaae Sønderby , Ole Winther

Memory is an important cognitive function for humans. How a brain with such a small power can complete such a complex memory function, the working mechanism behind this is undoubtedly fascinating. Engram theory views memory as the…

Distributed, Parallel, and Cluster Computing · Computer Science 2023-07-13 Hui Wei , Weihua Miao , Fushun Li

Machine learning on graphs is an important and ubiquitous task with applications ranging from drug design to friendship recommendation in social networks. The primary challenge in this domain is finding a way to represent, or encode, graph…

Social and Information Networks · Computer Science 2018-04-11 William L. Hamilton , Rex Ying , Jure Leskovec

Omics data, such as transcriptomics, proteomics, and metabolomics, provide critical insights into disease mechanisms and clinical outcomes. However, their high dimensionality, small sample sizes, and intricate biological networks pose major…

Machine Learning · Computer Science 2026-01-22 Tiantian Yang , Yuxuan Wang , Zhenwei Zhou , Ching-Ti Liu

Neural networks that compute over graph structures are a natural fit for problems in a variety of domains, including natural language (parse trees) and cheminformatics (molecular graphs). However, since the computation graph has a different…

Neural and Evolutionary Computing · Computer Science 2017-02-23 Moshe Looks , Marcello Herreshoff , DeLesley Hutchins , Peter Norvig