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Subgraph counting aims to count the occurrences of a subgraph template T in a given network G. The basic problem of computing structural properties such as counting triangles and other subgraphs has found applications in diverse domains.…

Distributed, Parallel, and Cluster Computing · Computer Science 2019-03-12 Langshi Chen , Jiayu Li , Ariful Azad , Lei Jiang , Madhav Marathe , Anil Vullikanti , Andrey Nikolaev , Egor Smirnov , Ruslan Israfilov , Judy Qiu

Advances in DNA sequencing technology have stimulated the development of algorithms and tools for processing very large collections of short strings (reads). Short-read alignment and assembly are among the most well-studied problems. Many…

Genomics · Quantitative Biology 2014-01-30 Chi-Man Liu , Ruibang Luo , Tak-Wah Lam

The Burrows-Wheeler-Transform (BWT), a reversible string transformation, is one of the fundamental components of many current data structures in string processing. It is central in data compression, as well as in efficient query algorithms…

Data Structures and Algorithms · Computer Science 2024-04-16 Sara Giuliani , Shunsuke Inenaga , Zsuzsanna Lipták , Nicola Prezza , Marinella Sciortino , Anna Toffanello

Highly-repetitive collections of strings are increasingly being amassed by genome sequencing and genetic variation experiments, as well as by storing all versions of human-generated files, like webpages and source code. Existing indexes for…

Data Structures and Algorithms · Computer Science 2016-04-22 Djamal Belazzougui , Fabio Cunial , Travis Gagie , Nicola Prezza , Mathieu Raffinot

The Burrows-Wheeler transform (BWT) is a permutation whose applications are prevalent in data compression and text indexing. The bijective BWT (BBWT) is a bijective variant of it. Although it is known that the BWT can be constructed in…

Data Structures and Algorithms · Computer Science 2021-04-23 Hideo Bannai , Juha Kärkkäinen , Dominik Köppl , Marcin Picatkowski

The recently introduced class of Wheeler graphs, inspired by the Burrows-Wheeler Transform (BWT) of a given string, admits an efficient index data structure for searching for subpaths with a given path label, and lifts the applicability of…

Formal Languages and Automata Theory · Computer Science 2020-02-25 Jarno Alanko , Giovanna D'Agostino , Alberto Policriti , Nicola Prezza

A recent paradigm shift in bioinformatics from a single reference genome to a pangenome brought with it several graph structures. These graph structures must implement operations, such as efficient construction from multiple genomes and…

Data Structures and Algorithms · Computer Science 2023-06-27 Andrej Baláž , Alessia Petescia

The field of succinct data structures has flourished over the last 16 years. Starting from the compressed suffix array (CSA) by Grossi and Vitter (STOC 2000) and the FM-index by Ferragina and Manzini (FOCS 2000), a number of generalizations…

Data Structures and Algorithms · Computer Science 2016-09-22 Djamal Belazzougui , Fabio Cunial , Juha Kärkkäinen , Veli Mäkinen

Run-length encoding Burrows-Wheeler Transformed strings, resulting in Run-Length BWT (RLBWT), is a powerful tool for processing highly repetitive strings. We propose a new algorithm for online RLBWT working in run-compressed space, which…

Data Structures and Algorithms · Computer Science 2017-10-17 Tatsuya Ohno , Yoshimasa Takabatake , Tomohiro I , Hiroshi Sakamoto

The input/output complexity, which is the complexity of data exchange between the main memory and the external memory, has been elaborately studied by a lot of former researchers. However, the existing works failed to consider the…

Computational Complexity · Computer Science 2022-08-23 Hengzhao Ma , Jianzhong Li , Xiangyu Gao , Tianpeng Gao

The Burrows-Wheeler Transform (BWT) is often taught in undergraduate courses on algorithmic bioinformatics, because it underlies the FM-index and thus important tools such as Bowtie and BWA. Its admirers consider the BWT a thing of beauty…

Data Structures and Algorithms · Computer Science 2022-08-23 Travis Gagie , Giovanni Manzini , Marinella Sciortino

Discovering the underlying structures present in large real world graphs is a fundamental scientific problem. In this paper we show that a graph's clique tree can be used to extract a hyperedge replacement grammar. If we store an ordering…

Social and Information Networks · Computer Science 2016-08-11 Salvador Aguiñaga , Rodrigo Palacios , David Chiang , Tim Weninger

We generalize the problem of reconstructing strings from their substring compositions first introduced by Acharya et al. in 2015 motivated by polymer-based advanced data storage systems utilizing mass spectrometry. Namely, we see strings as…

Combinatorics · Mathematics 2025-04-02 Antoine Dailly , Tuomo Lehtilä

The Watson-Crick complementary properties of DNA make DNA a useful tool for the self-assembly of various target complexes. Concepts from graph theory can be used to model the self-assembling process in which the vertices of the graph…

Combinatorics · Mathematics 2023-02-28 Gabriel Lopez , Cory Johnson

There are currently plenty of programs available for mapping short sequences (reads) to a genome. Most of them, however, including such popular and actively developed programs as Bowtie, BWA, TopHat and many others, are based on…

Genomics · Quantitative Biology 2019-08-06 Igor Seledtsov , Jaroslav Efremov , Vladimir Molodtsov , Victor Solovyev

Parameterized strings are a generalization of strings in that their characters are drawn from two different alphabets, where one is considered to be the alphabet of static characters and the other to be the alphabet of parameter characters.…

Data Structures and Algorithms · Computer Science 2022-09-01 Daiki Hashimoto , Diptarama Hendrian , Dominik Köppl , Ryo Yoshinaka , Ayumi Shinohara

Training recurrent neural networks to model long term dependencies is difficult. Hence, we propose to use external linguistic knowledge as an explicit signal to inform the model which memories it should utilize. Specifically, external…

Computation and Language · Computer Science 2017-03-09 Bhuwan Dhingra , Zhilin Yang , William W. Cohen , Ruslan Salakhutdinov

Subgraph GNNs are provably expressive neural architectures that learn graph representations from sets of subgraphs. Unfortunately, their applicability is hampered by the computational complexity associated with performing message passing on…

Machine Learning · Computer Science 2024-03-22 Beatrice Bevilacqua , Moshe Eliasof , Eli Meirom , Bruno Ribeiro , Haggai Maron

Ordering the collection of states of a given automaton starting from an order of the underlying alphabet is a natural move towards a computational treatment of the language accepted by the automaton. Along this path, Wheeler \emph{graphs}…

Formal Languages and Automata Theory · Computer Science 2021-06-14 Giovanna D'Agostino , Davide Martincigh , Alberto Policriti

A subgraph is constructed by using a subset of vertices and edges of a given graph. There exist many graph properties that are hereditary for subgraphs. Hence, researchers from different communities have paid a great deal of attention in…

Combinatorics · Mathematics 2023-06-06 Kai Siong Yow , Ningyi Liao , Siqiang Luo , Reynold Cheng , Chenhao Ma , Xiaolin Han