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Weighing particles above MegaDalton mass range has been a persistent challenge in commercial mass spectrometry. Recently, nanoelectromechanical systems-based mass spectrometry (NEMS-MS) has shown remarkable performance in this mass range,…

Applied Physics · Physics 2023-06-26 Batuhan E. Kaynak , Mohammed Alkhaled , Enise Kartal , Cenk Yanik , M. Selim Hanay

Nanoelectromechanical Systems (NEMS) have emerged as a promising technology for performing the mass spectrometry of large biomolecules and nanoparticles. As nanoscale objects land on NEMS sensor one by one, they induce resolvable shifts in…

Mesoscale and Nanoscale Physics · Physics 2019-07-24 Mert Yuksel , Ezgi Orhan , Cenk Yanik , Atakan B. Ari , Alper Demir , M. Selim Hanay

Mass spectrometry of intact nanoparticles and viruses can serve as a potent characterization tool for material science and biophysics. Inaccessible by widespread commercial techniques, the mass of single nanoparticles and viruses (>10MDa)…

One of the main challenges to overcome to perform nanomechanical Mass Spectrometry (NEMS-MS) analysis in a practical time frame stems from the size mismatch between the analyte beam and the extremely small nanomechanical detector area. We…

We describe the application of nanoelectromechanical systems (NEMS) to ultrasensitive mass detection. In these experiments, a modulated flux of atoms was adsorbed upon the surface of a 32.8 MHz NEMS resonator within an ultrahigh vacuum…

Other Condensed Matter · Physics 2009-11-10 K. L. Ekinci , X. M. H. Huang , M. L. Roukes

Nanomechanical spectroscopy (NMS) is a recently developed approach to determine optical absorption spectra of nanoscale materials via mechanical measurements. It is based on measuring changes in the resonance frequency of a membrane…

Nanoelectromechanical systems (NEMS) have generated considerable interest as inertial mass sensors. NEMS resonators have been used to weigh cells, biomolecules, and gas molecules, creating many new possibilities for biological and chemical…

Mesoscale and Nanoscale Physics · Physics 2012-04-13 J. Chaste , A. Eichler , J. Moser , G. Ceballos , R. Rurali , A. Bachtold

Mass spectrometry is a widespread approach to work out what are the constituents of a material. Atoms and molecules are removed from the material and collected, and subsequently, a critical step is to infer their correct identities based…

It has been demonstrated in the recent years that nanomechanical mass spectrometry was well suited for the analysis of specific high mass species such as viruses. Still, the exclusive use of one-dimensional devices such as vibrating beams…

Most technologies, including conventional mass spectrometry, struggle to measure the mass of particles in the MDa to GDa range. Although this mass range appears optimal for nanomechanical resonators, early nanomechanical-MS systems suffered…

Accelerator mass spectrometry (AMS) is a widely-used technique with multiple applications, including geology, molecular biology and archeology. In order to achieve a high dynamic range, AMS requires tandem accelerators and large magnets,…

Quantum Physics · Physics 2023-05-23 Radu Ionicioiu

The Alpha Magnetic Spectrometer (AMS) is a particle physics detector designed to measure charged cosmic ray spectra with energies up to the TeV region and with high energy photon detection capability up to few hundred GeV. It will be…

Astrophysics · Physics 2008-01-31 AMS Collaboration , Luísa Arruda

This article presents a comprehensive study and design methodology of co-integrated oscillators for nano mass sensing application based on resonant Nano-Electro-Mechanical-System (NEMS). In particular, it reports the capacitive with the…

Mesoscale and Nanoscale Physics · Physics 2015-05-14 Eric Colinet , Laurent Duraffourg , Sebastien Labarthe , Philippe Andreucci , Sebastien Hentz , Philippe Robert

Nanoelectromechanical systems, or NEMS, are MEMS scaled to submicron dimensions. In this size regime, it is possible to attain extremely high fundamental frequencies while simultaneously preserving very high mechanical responsivity (small…

Mesoscale and Nanoscale Physics · Physics 2007-05-23 M. L. Roukes

The coupling of an electron monochromator (EM) to a mass spectrometer (MS) has created a new analytical technique, EM-MS, for the investigation of electrophilic compounds. This method provides a powerful tool for molecular identification of…

The Alpha Magnetic Spectrometer (AMS) is a particle physics detector designed to operate on the International Space Station (ISS). The aim of AMS is the direct detection of charged particles in the rigidity range from 0.5 GV to few TV to…

Astrophysics · Physics 2007-05-23 Carmen Palomares

Magnetic particle spectroscopy (MPS) is one of the most versatile methods to characterize the magnetic properties of magnetic nanoparticles (MNPs). The excitation magnetic field is one of the most crucial factors that affects the MPS signal…

Applied Physics · Physics 2023-04-25 Shaoqi Sun , Shijie Sun , Lijun Xu , Jing Zhong

The VAMOS++ magnetic spectrometer is a multi-parametric system that integrates ion optical magnetic elements with a multi-detector stack. The magnetic elements, along with the tracking and timing detectors and the trajectory reconstruction…

Instrumentation and Detectors · Physics 2025-08-14 M. Rejmund , A. Lemasson

The knowledge of absolute fluxes of reactive species such as radicals or energetic ions to the surface is crucial for understanding the growth or etching of thin films. These species have due to their high reactivity very low densities and…

Plasma Physics · Physics 2011-05-16 Jan Benedikt , Dirk Ellerweg , Achim von Keudell

Magnetic nanoparticles (MNPs) have been extensively used as contrasts and tracers for bioimaging, heating sources for tumor therapy, carriers for controlled drug delivery, and labels for magnetic immunoassays. Here, we describe a MNP…

Applied Physics · Physics 2019-09-11 Kai Wu , Jinming Liu , Diqing Su , Renata Saha , Jian-Ping Wang
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