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This article discusses futility analyses for the MCP-Mod methodology. Formulas are derived for calculating predictive and conditional power for MCP-Mod, which also cover the case when longitudinal models are used allowing to utilize…

Methodology · Statistics 2024-07-01 Björn Bornkamp , Jie Zhou , Dong Xi , Weihua Cao

The latent class model is a powerful unsupervised clustering algorithm for categorical data. Many statistics exist to test the fit of the latent class model. However, traditional methods to evaluate those fit statistics are not always…

Methodology · Statistics 2018-01-30 Geert H. van Kollenburg , Joris Mulder , Jeroen K. Vermunt

This paper investigates the robustness of futility analyses in clinical trials when interim analysis population deviates from the target population. We demonstrate how population shifts can distort early stopping decisions and propose…

Methodology · Statistics 2025-07-31 Rui Jin , Cai Wu , Peter Mesenbrink

Hyperparameter optimization is crucial for obtaining peak performance of machine learning models. The standard protocol evaluates various hyperparameter configurations using a resampling estimate of the generalization error to guide…

Machine Learning · Statistics 2024-11-11 Thomas Nagler , Lennart Schneider , Bernd Bischl , Matthias Feurer

Software refactoring is the process of changing the structure of software without any alteration in its behavior and functionality. Presuming it is carried out in appropriate opportunities, refactoring enhances software quality…

Software Engineering · Computer Science 2023-01-20 Hanieh Khosravi , Abbas Rasoolzadegan

Bootstrap techniques (also called resampling computation techniques) have introduced new advances in modeling and model evaluation. Using resampling methods to construct a series of new samples which are based on the original data set,…

Statistics Theory · Mathematics 2007-06-13 Riadh Kallel , Marie Cottrell , Vincent Vigneron

One possible approach to tackle the class imbalance in classification tasks is to resample a training dataset, i.e., to drop some of its elements or to synthesize new ones. There exist several widely-used resampling methods. Recent research…

Machine Learning · Computer Science 2018-09-18 Smolyakov Dmitry , Alexander Korotin , Pavel Erofeev , Artem Papanov , Evgeny Burnaev

Combining the mutual information criterion with a forward feature selection strategy offers a good trade-off between optimality of the selected feature subset and computation time. However, it requires to set the parameter(s) of the mutual…

Machine Learning · Computer Science 2007-09-26 Damien François , Fabrice Rossi , Vincent Wertz , Michel Verleysen

Test-time training provides a new approach solving the problem of domain shift. In its framework, a test-time training phase is inserted between training phase and test phase. During test-time training phase, usually parts of the model are…

Machine Learning · Computer Science 2022-10-05 Bochao Zhang , Rui Shao , Jingda Du , PC Yuen

The correct use of model evaluation, model selection, and algorithm selection techniques is vital in academic machine learning research as well as in many industrial settings. This article reviews different techniques that can be used for…

Machine Learning · Computer Science 2020-11-12 Sebastian Raschka

In this paper, we develop an implementation of cross-validation for penalized linear mixed models. While these models have been proposed for correlated high-dimensional data, the current literature implicitly assumes that tuning parameter…

Methodology · Statistics 2025-03-19 Tabitha K. Peter , Patrick J. Breheny

Existing well investigated Predictive Process Monitoring techniques typically construct a predictive model based on past process executions, and then use it to predict the future of new ongoing cases, without the possibility of updating it…

Machine Learning · Computer Science 2023-10-26 Williams Rizzi , Chiara Di Francescomarino , Chiara Ghidini , Fabrizio Maria Maggi

The era of huge data necessitates highly efficient machine learning algorithms. Many common machine learning algorithms, however, rely on computationally intensive subroutines that are prohibitively expensive on large datasets. Oftentimes,…

Machine Learning · Computer Science 2023-09-26 Mo Tiwari

In this paper the accuracy and robustness of quality measures for the assessment of machine learning models are investigated. The prediction quality of a machine learning model is evaluated model-independent based on a cross-validation…

Machine Learning · Statistics 2024-10-07 Thomas Most , Lars Gräning , Sebastian Wolff

A common problem machine learning developers are faced with is overfitting, that is, fitting a pipeline too closely to the training data that the performance degrades for unseen data. Automated machine learning aims to free (or at least…

Machine Learning · Computer Science 2021-02-11 Benjamin Patrick Evans , Bing Xue , Mengjie Zhang

Cross-validation is a widely used technique for evaluating the performance of prediction models, ranging from simple binary classification to complex precision medicine strategies. It helps correct for optimism bias in error estimates,…

Fine-tuning a pre-trained model on a downstream task often degrades its original capabilities, a phenomenon known as "catastrophic forgetting". This is especially an issue when one does not have access to the data and recipe used to develop…

Machine Learning · Computer Science 2025-06-13 Sunny Sanyal , Hayden Prairie , Rudrajit Das , Ali Kavis , Sujay Sanghavi

Machine learning models are often used at test-time subject to constraints and trade-offs not present at training-time. For example, a computer vision model operating on an embedded device may need to perform real-time inference, or a…

Machine Learning · Statistics 2017-02-28 Augustus Odena , Dieterich Lawson , Christopher Olah

While many statistical models and methods are now available for network analysis, resampling network data remains a challenging problem. Cross-validation is a useful general tool for model selection and parameter tuning, but is not directly…

Methodology · Statistics 2020-05-04 Tianxi Li , Elizaveta Levina , Ji Zhu

In the Machine Learning (ML) model development lifecycle, training candidate models using an offline holdout dataset and identifying the best model for the given task is only the first step. After the deployment of the selected model,…

Machine Learning · Computer Science 2023-11-20 Jaykumar Kasundra , Claudia Schulz , Melicaalsadat Mirsafian , Stavroula Skylaki
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