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Survival analysis is a widely-used technique for analyzing time-to-event data in the presence of censoring. In recent years, numerous survival analysis methods have emerged which scale to large datasets and relax traditional assumptions…

Machine Learning · Computer Science 2023-11-06 Mert Ketenci , Shreyas Bhave , Noémie Elhadad , Adler Perotte

We introduce two new tools to assess the validity of statistical distributions. These tools are based on components derived from a new statistical quantity, the $comparison$ $curve$. The first tool is a graphical representation of these…

Methodology · Statistics 2024-05-16 Gilles R. Ducharme , Teresa Ledwina

Over the last decades, many prognostic models based on artificial intelligence techniques have been used to provide detailed predictions in healthcare. Unfortunately, the real-world observational data used to train and validate these models…

Machine Learning · Computer Science 2023-11-21 Alice Bernasconi , Alessio Zanga , Peter J. F. Lucas , Marco Scutari , Fabio Stella

Excess hazard modeling is one of the main tools in population-based cancer survival research. Indeed, this setting allows for direct modeling of the survival due to cancer even in the absence of reliable information on the cause of death,…

Methodology · Statistics 2022-04-12 A. Eletti , G. Marra , M. Quaresma , R. Radice , F. J. Rubio

The large majority of inferences drawn in empirical political research follow from model-based associations (e.g. regression). Here, we articulate the benefits of predictive modeling as a complement to this approach. Predictive models aim…

Methodology · Statistics 2016-12-20 Skyler J. Cranmer , Bruce A. Desmarais

Reliability (survival analysis, to biostatisticians) is a key ingredient for mak- ing decisions that mitigate the risk of failure. The other key ingredient is utility. A decision theoretic framework harnesses the two, but to invoke this…

Methodology · Statistics 2009-07-24 Nozer D. Singpurwalla

We propose a family of tests to assess the goodness-of-fit of a high-dimensional generalized linear model. Our framework is flexible and may be used to construct an omnibus test or directed against testing specific non-linearities and…

Methodology · Statistics 2019-11-14 Jana Janková , Rajen D. Shah , Peter Bühlmann , Richard J. Samworth

We consider the problem of model building for rare events prediction in longitudinal follow-up studies. In this paper, we compare several resampling methods to improve standard regression models on a real life example. We evaluate the…

Methodology · Statistics 2023-06-21 Pierre Druilhet , Mathieu Berthe , Stéphanie Léger

Survival prediction aims to evaluate the risk level of cancer patients. Existing methods primarily rely on pathology and genomics data, either individually or in combination. From the perspective of cancer pathogenesis, epigenetic changes,…

Machine Learning · Computer Science 2025-06-23 Haipeng Zhou , Sicheng Yang , Sihan Yang , Jing Qin , Lei Chen , Lei Zhu

The impact of machine learning models on healthcare will depend on the degree of trust that healthcare professionals place in the predictions made by these models. In this paper, we present a method to provide people with clinical expertise…

Machine Learning · Computer Science 2021-03-05 Aniruddh Raghu , John Guttag , Katherine Young , Eugene Pomerantsev , Adrian V. Dalca , Collin M. Stultz

In cancer research there is much interest in building and validating outcome predicting outcomes to support treatment decisions. However, because most outcome prediction models are developed and validated without regard to the causal…

Machine Learning · Computer Science 2024-04-29 Wouter A. C. van Amsterdam , Pim A. de Jong , Joost J. C. Verhoeff , Tim Leiner , Rajesh Ranganath

Probabilistic models analyze data by relying on a set of assumptions. Data that exhibit deviations from these assumptions can undermine inference and prediction quality. Robust models offer protection against mismatch between a model's…

Machine Learning · Statistics 2018-06-20 Yixin Wang , Alp Kucukelbir , David M. Blei

A variety of works in the literature strive to uncover the factors associated with survival behaviour. However, the computational tools to provide such information are global models designed to predict if or when a (survival) event will…

Machine Learning · Computer Science 2021-09-07 Juliana Barcellos Mattos , Paulo S. G. de Mattos Neto , Renato Vimieiro

Discrimination and calibration represent two important properties of survival analysis, with the former assessing the model's ability to accurately rank subjects and the latter evaluating the alignment of predicted outcomes with actual…

Machine Learning · Computer Science 2024-06-04 Shi-ang Qi , Yakun Yu , Russell Greiner

Many methods of estimating causal models do not provide estimates of confidence in the resulting model. In this work, a metric is proposed for validating the output of a causal model fit; the robustness of the model structure with resampled…

Suppose that a sequence of data points follows a distribution of a certain parametric form, but that one or more of the underlying parameters may change over time. This paper addresses various natural questions in such a framework. We…

Methodology · Statistics 2026-05-19 Nils Lid Hjort , Alex J. Koning

Longitudinal and time-to-event data are often analyzed in biomarker research to study the association between the longitudinal biomarker measurements and the event-time outcome, in which the longitudinal information contributes to the…

Methodology · Statistics 2025-09-09 Minzee Kim , Joel A. Dubin

Survivor bias in observational data leads the optimization of recommender systems towards local optima. Currently most solutions re-mines existing human-system collaboration patterns to maximize longer-term satisfaction by reinforcement…

Machine Learning · Computer Science 2023-10-31 Jialin Liu , Xinyan Su , Peng Zhou , Xiangyu Zhao , Jun Li

In this paper, we propose the use of causal inference techniques for survival function estimation and prediction for subgroups of the data, upto individual units. Tree ensemble methods, specifically random forests were modified for this…

Econometrics · Economics 2018-03-23 Vikas Ramachandra

Traditional survival models such as the Cox proportional hazards model are typically based on scalar or categorical clinical features. With the advent of increasingly large image datasets, it has become feasible to incorporate quantitative…

Computer Vision and Pattern Recognition · Computer Science 2020-01-09 Christoph Haarburger , Philippe Weitz , Oliver Rippel , Dorit Merhof