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Epileptic seizures are characterized by abnormal and excessive neural activity, where cortical network dynamics seem to become unstable. However, most of the time, during seizure-free periods, cortex of epilepsy patients shows perfectly…

Neurons and Cognition · Quantitative Biology 2021-04-06 Annika Hagemann , Jens Wilting , Bita Samimizad , Florian Mormann , Viola Priesemann

A system driven in the vicinity of its critical point by varying a relevant field in an arbitrary function of time is a generic system that possesses a long relaxation time compared with the driving time scale and thus represents a large…

Statistical Mechanics · Physics 2016-10-26 Baoquan Feng , Shuai Yin , Fan Zhong

We discuss the complex dynamics of a non-linear random networks model, as a function of the connectivity k between the elements of the network. We show that this class of networks exhibit an order-chaos phase transition for a critical…

Adaptation and Self-Organizing Systems · Physics 2013-05-29 M. Andrecut , S. A. Kauffman

We present a neuronal network model inspired by the Ising model, where each neuron is a binary spin ($s_i = \pm1$) interacting with its neighbors on a 2D lattice. Updates are asynchronous and follow Metropolis dynamics, with a…

Neurons and Cognition · Quantitative Biology 2025-06-10 Sajedeh Sarmastani , Maliheh Ghodrat , Yousef Jamali

Epilepsy is one of the most common neurological disorders globally, affecting millions of individuals. Despite significant advancements, the precise mechanisms underlying this condition remain largely unknown, making accurately predicting…

Systems and Control · Electrical Eng. & Systems 2024-04-05 Yuzhen Qin , Ahmed El-Gazzar , Danielle S. Bassett , Fabio Pasqualetti , Marcel van Gerven

Transient or partial synchronization can be used to do computations, although a fully synchronized network is frequently related to epileptic seizures. Here, we propose a homeostatic mechanism that is capable of maintaining a neuronal…

Adaptation and Self-Organizing Systems · Physics 2024-05-21 Sue L. Rhâmidda , Mauricio Girardi-Schappo , Osame Kinouchi

Non-equilibrium critical phenomena generally exist in many dynamic systems, like chemical reactions and some driven-dissipative {reactive} particle systems. Here, by using computer simulation and theoretical analysis, we demonstrate the…

Soft Condensed Matter · Physics 2021-05-26 Qun-Li Lei , Hao Hu , Ran Ni

Novel computing hardwares are necessary to keep up with today's increasing demand for data storage and processing power. In this research project, we turn to the brain for inspiration to develop novel computing substrates that are…

Neurons and Cognition · Quantitative Biology 2019-07-05 Kristine Heiney , Vibeke Devold Valderhaug , Ioanna Sandvig , Axel Sandvig , Gunnar Tufte , Hugo Lewi Hammer , Stefano Nichele

A prominent hypothesis in neuroscience proposes that brains achieve optimal performance by operating near a critical point. However, this framework, which often assumes a universal critical point, fails to account for the extensive…

Neurons and Cognition · Quantitative Biology 2025-12-04 Kejian Wu , Dante R. Chialvo , Changsong Zhou , Lianchun Yu

Hallmarks of criticality, such as power-laws and scale invariance, have been empirically found in cortical networks and it has been conjectured that operating at criticality entails functional advantages, such as optimal computational…

Disordered Systems and Neural Networks · Physics 2014-11-13 Paolo Moretti , Miguel A. Muñoz

The criticality hypothesis posits that biological neural networks operate near a phase transition, yet within standard Gaussian mean-field theories this regime appears fragile and requires fine tuning. Here we show that heavy-tailed…

Biological Physics · Physics 2026-03-20 Ryota Kojima

In this work, we present a mathematical model for cyclic and sequential patterns of brain activity, combining heteroclinic dynamics with discrete neural-field models. We first show that spatial-discrete neural-field equations with…

Dynamical Systems · Mathematics 2026-05-05 M Virginia Bolelli , Luca Greco , Dario Prandi

Cortical activity in-vivo displays relaxational time scales much longer than the membrane time constant of the neurons or the deactivation time of ionotropic synaptic conductances. The mechanisms responsible for such slow dynamics are not…

Disordered Systems and Neural Networks · Physics 2025-08-07 Ferdinand Tixidre , Gianluigi Mongillo , Alessandro Torcini

Neuronal firing activities have attracted a lot of attention since a large population of spatiotemporal patterns in the brain is the basis for adaptive behavior and can also reveal the signs for various neurological disorders including…

Neurons and Cognition · Quantitative Biology 2017-03-13 Wenyuan Li , Igor V. Ovchinnikov , Honglin Chen , Zhe Wang , Albert Lee , Hochul Lee , Carlos Cepeda , Robert N. Schwartz , Karlheinz Meier , Kang L. Wang

We assess electrical brain dynamics before, during, and after one-hundred human epileptic seizures with different anatomical onset locations by statistical and spectral properties of functionally defined networks. We observe a concave-like…

Neurons and Cognition · Quantitative Biology 2013-11-25 Kaspar A. Schindler , Stephan Bialonski , Marie-Therese Horstmann , Christian E. Elger , Klaus Lehnertz

Dynamical balance of excitation and inhibition is usually invoked to explain the irregular low firing activity observed in the cortex. We propose a robust nonlinear balancing mechanism for a random network of spiking neurons, which works…

Disordered Systems and Neural Networks · Physics 2025-05-29 Antonio Politi , Alessandro Torcini

Extended numerical simulations of threshold models have been performed on a human brain network with N=836733 connected nodes available from the Open Connectome project. While in case of simple threshold models a sharp discontinuous phase…

Disordered Systems and Neural Networks · Physics 2016-12-28 Géza Ódor

The interplay between cytoskeletal architecture and the nonlinearity of the interactions due to bucklable filaments plays a key role in modulating the cell's mechanical stability and affecting its structural rearrangements. We study a model…

Statistical Mechanics · Physics 2011-07-01 Shenshen Wang , Tongye Shen , Peter G. Wolynes

The critical brain hypothesis receives increasing support from recent experimental results. It postulates that the brain is at a critical point between an ordered and a chaotic regime, sometimes referred to as the "edge of chaos." Another…

Disordered Systems and Neural Networks · Physics 2022-02-08 Lorenz Baumgarten , Stefan Bornholdt

Neural mass models are used to simulate cortical dynamics and to explain the electrical and magnetic fields measured using electro- and magnetoencephalography. Simulations evince a complex phase-space structure for these kinds of models;…

Neurons and Cognition · Quantitative Biology 2022-08-25 Gerald Cooray , Richard Rosch , Karl Friston