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Multicellular systems play a key role in bioprocess and biomedical engineering. Cell ensembles encountered in these setups show phenotypic variability like size and biochemical composition. As this variability may result in undesired…

Systems and Control · Computer Science 2018-07-16 Armin Küper , Robert Dürr , Steffen Waldherr

In this contribution, a design of a synthetic calibration genetic circuit to characterize the relative strength of different sensing promoters is proposed and its specifications and performance are analyzed via an effective mathematical…

Molecular Networks · Quantitative Biology 2026-02-06 D. Gamermann , A. Montagud , P. Aparicio , E. Navarro , J. Triana , F. R. Villatoro , J. F. Urchueguía , P. Fernández de Córdoba

Distribution regression refers to the supervised learning problem where labels are only available for groups of inputs instead of individual inputs. In this paper, we develop a rigorous mathematical framework for distribution regression…

Machine Learning · Computer Science 2021-09-30 Maud Lemercier , Cristopher Salvi , Theodoros Damoulas , Edwin V. Bonilla , Terry Lyons

This study proposes a data condensation method for multivariate kernel density estimation by genetic algorithm. First, our proposed algorithm generates multiple subsamples of a given size with replacement from the original sample. The…

Methodology · Statistics 2022-03-04 Kiheiji Nishida

Computer vision is hard because of a large variability in lighting, shape, and texture; in addition the image signal is non-additive due to occlusion. Generative models promised to account for this variability by accurately modelling the…

Computer Vision and Pattern Recognition · Computer Science 2015-03-10 Varun Jampani , Sebastian Nowozin , Matthew Loper , Peter V. Gehler

While biological vision systems rely heavily on feedback connections to iteratively refine perception, most artificial neural networks remain purely feedforward, processing input in a single static pass. In this work, we propose a…

Computer Vision and Pattern Recognition · Computer Science 2025-07-15 David Calhas , Arlindo L. Oliveira

One approach for feedback control using high dimensional and rich sensor measurements is to classify the measurement into one out of a finite set of situations, each situation corresponding to a (known) control action. This approach…

Optimization and Control · Mathematics 2019-03-12 Hasan A. Poonawala , Niklas Lauffer , Ufuk Topcu

The ability to learn and respond to recurrent events depends on the capacity to remember transient biological signals received in the past. Moreover, it may be desirable to remember or ignore these transient signals conditioned upon other…

Molecular Networks · Quantitative Biology 2010-09-17 Georg Fritz , Nicolas E. Buchler , Terence Hwa , Ulrich Gerland

Generating synthetic datasets that accurately reflect real-world observational data is critical for evaluating causal estimators, but it remains a challenging task. Existing generative methods offer a solution by producing synthetic…

Machine Learning · Computer Science 2026-04-07 Pracheta Amaranath , Vinitra Muralikrishnan , Amit Sharma , David Jensen

We propose distributed algorithms for two well-established problems that operate efficiently under extremely harsh conditions. Our algorithms achieve state-of-the-art performance in a simple and novel way. Our algorithm for maximal…

Distributed, Parallel, and Cluster Computing · Computer Science 2016-01-19 Peter Jeavons , Alex Scott , Lei Xu

The performance of pre-trained masked diffusion models is often constrained by their sampling procedure, which makes decisions irreversible and struggles in low-step generation regimes. We introduce a novel sampling algorithm that works…

Genetic circuit design is a well-studied problem in synthetic biology. Ever since the first genetic circuits -- the repressilator and the toggle switch -- were designed and implemented, many advances have been made in this area of research.…

Molecular Networks · Quantitative Biology 2021-11-09 Debomita Chakraborty , Raghunathan Rengaswamy , Karthik Raman

Cluster analysis of biological samples using gene expression measurements is a common task which aids the discovery of heterogeneous biological sub-populations having distinct mRNA profiles. Several model-based clustering algorithms have…

Methodology · Statistics 2012-01-30 Alberto Cozzini , Ajay Jasra , Giovanni Montana

An interpretable generative model for handwritten digits synthesis is proposed in this work. Modern image generative models, such as Generative Adversarial Networks (GANs) and Variational Autoencoders (VAEs), are trained by backpropagation…

Computer Vision and Pattern Recognition · Computer Science 2018-11-13 Yao Zhu , Saksham Suri , Pranav Kulkarni , Yueru Chen , Jiali Duan , C. -C. Jay Kuo

We focus on generative autoencoders, such as variational or adversarial autoencoders, which jointly learn a generative model alongside an inference model. Generative autoencoders are those which are trained to softly enforce a prior on the…

Machine Learning · Computer Science 2017-01-13 Antonia Creswell , Kai Arulkumaran , Anil Anthony Bharath

Well-trained classifiers and their complete weight distributions provide us with a well-motivated and practicable method to test generative networks in particle physics. We illustrate their benefits for distribution-shifted jets,…

High Energy Physics - Phenomenology · Physics 2024-01-31 Ranit Das , Luigi Favaro , Theo Heimel , Claudius Krause , Tilman Plehn , David Shih

The machine learning community has mainly relied on real data to benchmark algorithms as it provides compelling evidence of model applicability. Evaluation on synthetic datasets can be a powerful tool to provide a better understanding of a…

Machine Learning · Computer Science 2022-11-01 Florence Regol , Anja Kroon , Mark Coates

Most generative models of audio directly generate samples in one of two domains: time or frequency. While sufficient to express any signal, these representations are inefficient, as they do not utilize existing knowledge of how sound is…

Machine Learning · Computer Science 2020-01-15 Jesse Engel , Lamtharn Hantrakul , Chenjie Gu , Adam Roberts

Accurately interpreting cardiac auscultation signals plays a crucial role in diagnosing and managing cardiovascular diseases. However, the paucity of labelled data inhibits classification models' training. Researchers have turned to…

Sound · Computer Science 2025-06-18 Leigh Abbott , Milan Marocchi , Matthew Fynn , Yue Rong , Sven Nordholm

Generating training examples for supervised tasks is a long sought after goal in AI. We study the problem of heart signal electrocardiogram (ECG) synthesis for improved heartbeat classification. ECG synthesis is challenging: the generation…

Signal Processing · Electrical Eng. & Systems 2020-06-30 Tomer Golany , Daniel Freedman , Kira Radinsky