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We consider the problem of designing synthetic cells to achieve a complex goal (e.g., mimicking the immune system by seeking invaders) in a complex environment (e.g., the circulatory system), where they might have to change their control…

Robotics · Computer Science 2020-03-10 Ana Pervan , Todd Murphey

Neural receivers have demonstrated strong performance in wireless communication systems. However, their effectiveness typically depends on access to large-scale, scenario-specific channel data for training, which is often difficult to…

Information Theory · Computer Science 2025-11-04 Xingyu Zhou , Le Liang , Xinjie Li , Jing Zhang , Peiwen Jiang , Xiao Li , Shi Jin

Akin to electric circuits, we construct biocircuits that are manipulated by cutting and assembling channels through which stochastic information flows. This diagrammatic manipulation allows us to create a method which constructs networks by…

Molecular Networks · Quantitative Biology 2016-11-15 Cameron Ferwerda , Ovidiu Lipan

Generative adversarial networks (GANs) are deep neural networks that allow us to sample from an arbitrary probability distribution without explicitly estimating the distribution. There is a generator that takes a latent vector as input and…

Machine Learning · Computer Science 2021-06-22 Alper Ahmetoğlu , Ethem Alpaydın

We tackle the problem of Selective Classification where the objective is to achieve the best performance on a predetermined ratio (coverage) of the dataset. Recent state-of-the-art selective methods come with architectural changes either…

Machine Learning · Computer Science 2023-03-03 Leo Feng , Mohamed Osama Ahmed , Hossein Hajimirsadeghi , Amir Abdi

In this paper, we consider statistical inference with generalized linear models in high dimensions under a longitudinal clustered data framework. Specifically, we propose a de-sparsified version of an initial Dantzig-type regularized…

Methodology · Statistics 2025-08-13 Nathan Huey

We develop a method for generating causal post-hoc explanations of black-box classifiers based on a learned low-dimensional representation of the data. The explanation is causal in the sense that changing learned latent factors produces a…

Machine Learning · Computer Science 2020-10-23 Matthew O'Shaughnessy , Gregory Canal , Marissa Connor , Mark Davenport , Christopher Rozell

State-of-the-art techniques of artificial intelligence, in particular deep learning, are mostly data-driven. However, collecting and manually labeling a large scale dataset is both difficult and expensive. A promising alternative is to…

Computer Vision and Pattern Recognition · Computer Science 2018-07-31 Qi Chen , Weichao Qiu , Yi Zhang , Lingxi Xie , Alan Yuille

In this paper, we make a bold attempt toward an ambitious task: given a pre-trained classifier, we aim to reconstruct an image generator, without relying on any data samples. From a black-box perspective, this challenge seems intractable,…

Machine Learning · Computer Science 2023-12-06 Runpeng Yu , Xinchao Wang

Despite significant advances in deep models for music generation, the use of these techniques remains restricted to expert users. Before being democratized among musicians, generative models must first provide expressive control over the…

Sound · Computer Science 2023-02-28 Ninon Devis , Nils Demerlé , Sarah Nabi , David Genova , Philippe Esling

Quantifying biomechanical properties of the human vasculature could deepen our understanding of cardiovascular diseases. Standard nonlinear regression in constitutive modeling requires considerable high-quality data and an explicit form of…

Machine Learning · Computer Science 2023-09-26 Minglang Yin , Zongren Zou , Enrui Zhang , Cristina Cavinato , Jay D. Humphrey , George Em Karniadakis

This work considers distributed sensing and transmission of sporadic random samples. Lower bounds are derived for the reconstruction error of a single normally or uniformly-distributed finite-dimensional vector imperfectly measured by a…

Information Theory · Computer Science 2015-11-20 Ayşe Ünsal , Raymond Knopp

The spread of microbial infections is governed by the self-organization of bacteria on surfaces. Limitations of live imaging techniques make collective behaviors in clinically relevant systems challenging to quantify. Here, novel…

Biological Physics · Physics 2024-07-19 Vincent Hickl , Abid Khan , René M. Rossi , Bruno F. B. Silva , Katharina Maniura-Weber

This paper presents an automatic formal controller synthesis method for nonlinear sampled-data systems with safety and reachability specifications. Fundamentally, the presented method is not restricted to polynomial systems and controllers.…

Systems and Control · Computer Science 2018-12-07 Cees F. Verdier , Manuel Mazo

Distributionally balanced sampling designs are low-discrepancy probability designs obtained by minimizing the expected discrepancy between the auxiliary-variable distribution of a random sample and the target population distribution.…

Methodology · Statistics 2026-03-26 Anton Grafström , Wilmer Prentius

We present a conditional generative model to learn variation in cell and nuclear morphology and the location of subcellular structures from microscopy images. Our model generalizes to a wide range of subcellular localization and allows for…

Machine Learning · Statistics 2017-05-02 Gregory R. Johnson , Rory M. Donovan-Maiye , Mary M. Maleckar

Engineering simple, artificial models of living cells allows synthetic biologists to study cellular functions under well-controlled conditions. Reconstituting multicellular behaviors with synthetic cell-mimics is still a challenge because…

Biomolecules · Quantitative Biology 2021-04-29 Imre Banlaki , Francois-Xavier Lehr , Henrike Niederholtmeyer

We introduce a class of auto-encoder neural networks tailored to data from the natural exponential family (e.g., count data). The architectures are inspired by the problem of learning the filters in a convolutional generative model with…

Machine Learning · Computer Science 2020-06-30 Bahareh Tolooshams , Andrew H. Song , Simona Temereanca , Demba Ba

We demonstrate in this paper that a generative model can be designed to perform classification tasks under challenging settings, including adversarial attacks and input distribution shifts. Specifically, we propose a conditional variational…

Computer Vision and Pattern Recognition · Computer Science 2019-02-12 Houpu Yao , Malcolm Regan , Yezhou Yang , Yi Ren

Unsupervised training of generative models is a machine learning task that has many applications in scientific computing. In this work we evaluate the efficacy of using quantum circuit-based generative models to generate synthetic data of…

Quantum Physics · Physics 2022-11-23 Andrea Delgado , Kathleen E. Hamilton