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For practical construction of complex synthetic genetic networks able to perform elaborate functions it is important to have a pool of relatively simple "bio-bricks" with different functionality which can be compounded together. To…

Molecular Networks · Quantitative Biology 2018-11-21 Oleg Kanakov , Roman Kotelnikov , Ahmed Alsaedi , Lev Tsimring , Ramon Huerta , Alexey Zaikin , Mikhail Ivanchenko

Deep learning models are known to be overconfident in their predictions on out of distribution inputs. There have been several pieces of work to address this issue, including a number of approaches for building Bayesian neural networks, as…

Machine Learning · Statistics 2018-12-04 Kumar Sricharan , Ashok Srivastava

Genetic oscillators are a major theme of interest in the emerging field of synthetic biology. Until recently, most work has been carried out using intra-cellular oscillators, but this approach restricts the broader applicability of such…

Cell Behavior · Quantitative Biology 2010-07-28 Angel Goni-Moreno , Martyn Amos

Although deep neural networks are effective on supervised learning tasks, they have been shown to be brittle. They are prone to overfitting on their training distribution and are easily fooled by small adversarial perturbations. In this…

Machine Learning · Computer Science 2020-10-07 Laëtitia Shao , Yang Song , Stefano Ermon

We consider the problem of training generative models with deep neural networks as generators, i.e. to map latent codes to data points. Whereas the dominant paradigm combines simple priors over codes with complex deterministic models, we…

Machine Learning · Statistics 2017-07-31 Yannic Kilcher , Aurélien Lucchi , Thomas Hofmann

Associative learning is one of the key mechanisms displayed by living organisms in order to adapt to their changing environments. It was early recognized to be a general trait of complex multicellular organisms but also found in "simpler"…

Cell Behavior · Quantitative Biology 2017-01-24 Javier Macia , Blai Vidiella , Ricard Sole

In quantum many-body systems, measurements can induce qualitative new features, but their simulation is hindered by the exponential complexity involved in sampling the measurement results. We propose to use machine learning to assist the…

Quantum Physics · Physics 2024-12-03 Yuchen Zhu , Molei Tao , Yuebo Jin , Xie Chen

We train a network to generate mappings between training sets and classification policies (a 'classifier generator') by conditioning on the entire training set via an attentional mechanism. The network is directly optimized for test set…

Machine Learning · Computer Science 2018-04-02 Nicholas Guttenberg , Ryota Kanai

The discriminative approach to classification using deep neural networks has become the de-facto standard in various fields. Complementing recent reservations about safety against adversarial examples, we show that conventional…

Machine Learning · Computer Science 2018-07-25 William Wang , Angelina Wang , Aviv Tamar , Xi Chen , Pieter Abbeel

We consider the problem of training generative models with deep neural networks as generators, i.e. to map latent codes to data points. Whereas the dominant paradigm combines simple priors over codes with complex deterministic models, we…

Machine Learning · Computer Science 2018-01-09 Yannic Kilcher , Aurelien Lucchi , Thomas Hofmann

Many dynamic ensemble selection (DES) methods are known in the literature. A previously-developed by the authors, method consists in building a randomized classifier which is treated as a model of the base classifier. The model is…

Machine Learning · Computer Science 2021-09-17 Pawel Trajdos , Marek Kurzynski

Deep networks have shown great performance in classification tasks. However, the parameters learned by the classifier networks usually discard stylistic information of the input, in favour of information strictly relevant to classification.…

Neural and Evolutionary Computing · Computer Science 2018-03-07 Rey Wiyatno , Jeff Orchard

In bacterial populations, cells are able to cooperate in order to yield complex collective functionalities. Interest in population-level cellular behaviour is increasing, due to both our expanding knowledge of the underlying biological…

Multiagent Systems · Computer Science 2012-11-07 Angel Goni-Moreno , Martyn Amos

Neural network based generative models with discriminative components are a powerful approach for semi-supervised learning. However, these techniques a) cannot account for model uncertainty in the estimation of the model's discriminative…

Machine Learning · Statistics 2017-06-30 Jonathan Gordon , José Miguel Hernández-Lobato

The research community continues to seek increasingly more advanced synthetic data generators to reliably evaluate the strengths and limitations of machine learning methods. This work aims to increase the availability of datasets…

Machine Learning · Computer Science 2026-01-30 Joanna Komorniczak

Living organisms rely on endogenous feedback mechanisms to maintain homeostasis in the presence of uncertainty and environmental fluctuations. An emerging challenge at the interface of control systems engineering and synthetic biology is…

Systems and Control · Electrical Eng. & Systems 2026-02-24 Mario di Bernardo

A common assumption in causal modeling posits that the data is generated by a set of independent mechanisms, and algorithms should aim to recover this structure. Standard unsupervised learning, however, is often concerned with training a…

Machine Learning · Computer Science 2019-03-05 Francesco Locatello , Damien Vincent , Ilya Tolstikhin , Gunnar Rätsch , Sylvain Gelly , Bernhard Schölkopf

We consider the problem of distributed feature quantization, where the goal is to enable a pretrained classifier at a central node to carry out its classification on features that are gathered from distributed nodes through communication…

Machine Learning · Computer Science 2019-11-04 Osama A. Hanna , Yahya H. Ezzeldin , Tara Sadjadpour , Christina Fragouli , Suhas Diggavi

Microbiological systems evolve to fulfill their tasks with maximal efficiency. The immune system is a remarkable example, where self-non self distinction is accomplished by means of molecular interaction between self proteins and antigens,…

Cell Behavior · Quantitative Biology 2013-08-26 Marcio Argollo de Menezes , Edgardo Brigatti , Veit Schwämmle

We investigate the ability of a genetic algorithm to design cellular automata that perform computations. The computational strategies of the resulting cellular automata can be understood using a framework in which ``particles'' embedded in…

adap-org · Physics 2015-06-30 James P. Crutchfield , Melanie Mitchell , Rajarshi Das
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