English
Related papers

Related papers: A Simple Data-Adaptive Probabilistic Variant Calli…

200 papers

Data efficient voice cloning aims at synthesizing target speaker's voice with only a few enrollment samples at hand. To this end, speaker adaptation and speaker encoding are two typical methods based on base model trained from multiple…

Audio and Speech Processing · Electrical Eng. & Systems 2020-08-12 Jian Cong , Shan Yang , Lei Xie , Guoqiao Yu , Guanglu Wan

Next Generation Sequencing can sample the whole genome (WGS) or the 1-2% of the genome that codes for proteins called the whole exome (WES). Machine learning approaches to variant calling achieve high accuracy in WGS data, but the reduced…

Genomics · Quantitative Biology 2019-11-19 Ren Yi , Pi-Chuan Chang , Gunjan Baid , Andrew Carroll

Additive Noise Models (ANMs) are a common model class for causal discovery from observational data and are often used to generate synthetic data for causal discovery benchmarking. Specifying an ANM requires choosing all parameters,…

Machine Learning · Statistics 2023-11-02 Alexander G. Reisach , Myriam Tami , Christof Seiler , Antoine Chambaz , Sebastian Weichwald

While measurement advances now allow extensive surveys of gene activity (large numbers of genes across many samples), interpretation of these data is often confounded by noise -- expression counts can differ strongly across samples due to…

We present a simple noise-robust margin-based active learning algorithm to find homogeneous (passing the origin) linear separators and analyze its error convergence when labels are corrupted by noise. We show that when the imposed noise…

Machine Learning · Statistics 2015-11-25 Yining Wang , Aarti Singh

Standing genetic variation provides a rich reservoir of potentially useful mutations facilitating the adaptation to novel environments. Experimental evolution studies have demonstrated that rapid and strong phenotypic responses to selection…

Populations and Evolution · Quantitative Biology 2013-07-19 Robert Kofler , Christian Schlötterer

Motivation: Whole-genome high-coverage sequencing has been widely used for personal and cancer genomics as well as in various research areas. However, in the lack of an unbiased whole-genome truth set, the global error rate of variant calls…

Genomics · Quantitative Biology 2018-07-27 Heng Li

Noise in data appears to be inevitable in most real-world machine learning applications and would cause severe overfitting problems. Not only can data features contain noise, but labels are also prone to be noisy due to human input. In this…

Machine Learning · Computer Science 2025-05-09 Weipeng Huang , Qin Li , Yang Xiao , Cheng Qiao , Tie Cai , Junwei Liang , Neil J. Hurley , Guangyuan Piao

An important stage of most state-of-the-art (SOTA) noisy-label learning methods consists of a sample selection procedure that classifies samples from the noisy-label training set into noisy-label or clean-label subsets. The process of…

Computer Vision and Pattern Recognition · Computer Science 2024-11-05 Filipe R. Cordeiro , Gustavo Carneiro

In this work, we propose a novel variational Bayesian adaptive learning approach for cross-domain knowledge transfer to address acoustic mismatches between training and testing conditions, such as recording devices and environmental noise.…

Audio and Speech Processing · Electrical Eng. & Systems 2025-01-28 Hu Hu , Sabato Marco Siniscalchi , Chao-Han Huck Yang , Chin-Hui Lee

This paper addresses variational data assimilation from a learning point of view. Data assimilation aims to reconstruct the time evolution of some state given a series of observations, possibly noisy and irregularly-sampled. Using automatic…

Computational Physics · Physics 2021-11-10 Ronan Fablet , Bertrand Chapron , Lucas. Drumetz , Etienne Memin , Olivier Pannekoucke , Francois Rousseau

Sample selection is an effective strategy to mitigate the effect of label noise in robust learning. Typical strategies commonly apply the small-loss criterion to identify clean samples. However, those samples lying around the decision…

Computer Vision and Pattern Recognition · Computer Science 2022-08-25 Qi Wei , Haoliang Sun , Xiankai Lu , Yilong Yin

Nonlinear vector autoregression (NVAR) and reservoir computing (RC) have shown promise in forecasting chaotic dynamical systems, such as the Lorenz-63 model and El Nino-Southern Oscillation. However, their reliance on fixed nonlinear…

Machine Learning · Computer Science 2025-12-02 Azimov Sherkhon , Susana Lopez-Moreno , Eric Dolores-Cuenca , Sieun Lee , Sangil Kim

Adaptive sampling algorithms are modern and efficient methods that dynamically adjust the sample size throughout the optimization process. However, they may encounter difficulties in risk-averse settings, particularly due to the challenge…

Optimization and Control · Mathematics 2025-02-17 Sandra Pieraccini , Tommaso Vanzan

A noisy training set usually leads to the degradation of the generalization and robustness of neural networks. In this paper, we propose a novel theoretically guaranteed clean sample selection framework for learning with noisy labels.…

Machine Learning · Computer Science 2023-11-30 Yikai Wang , Yanwei Fu , Xinwei Sun

Background: While benchmarks on short-read variant calling suggest low error rate below 0.5%, they are only applicable to predefined confident regions. For a human sample without such regions, the error rate could be 10 times higher.…

Genomics · Quantitative Biology 2025-09-23 Heng Li

A framework is introduced for solving a sequence of slowly changing optimization problems, including those arising in regression and classification applications, using optimization algorithms such as stochastic gradient descent (SGD). The…

Machine Learning · Computer Science 2015-09-25 Craig Wilson , Venugopal V. Veeravalli

The assumption that training and testing samples are generated from the same distribution does not always hold for real-world machine-learning applications. The procedure of tackling this discrepancy between the training (source) and…

Machine Learning · Computer Science 2018-12-05 Debasmit Das , C. S. George Lee

Most neural-network based speaker-adaptive acoustic models for speech synthesis can be categorized into either layer-based or input-code approaches. Although both approaches have their own pros and cons, most existing works on speaker…

Audio and Speech Processing · Electrical Eng. & Systems 2018-10-02 Hieu-Thi Luong , Junichi Yamagishi

We present SVCnet, a system for modelling speaker variability. Encoder Neural Networks specialized for each speech sound produce low dimensionality models of acoustical variation, and these models are further combined into an overall model…

Sound · Computer Science 2022-11-17 Michael Witbrock , Patrick Haffner