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Medical researchers have solved the problem of estimating the sensitivity and specificity of binary medical diagnostic tests without gold standard tests for comparison. That problem is the same as estimating confusion matrices for…

Machine Learning · Statistics 2022-12-29 Richard Evans

The interplay between missing data and model uncertainty -- two classic statistical problems -- leads to primary questions that we formally address from an objective Bayesian perspective. For the general regression problem, we discuss the…

The usual advantages put forward for including nullability declarations in the type systems of programming languages are that they improve program reliability or performance. But there is another, entirely different, reason for doing so. In…

Programming Languages · Computer Science 2011-08-25 William Harrison , Tim Walsh , Paul Biggar

It is often said that the fundamental problem of causal inference is a missing data problem -- the comparison of responses to two hypothetical treatment assignments is made difficult because for every experimental unit only one potential…

Methodology · Statistics 2024-11-21 Razieh Nabi , Rohit Bhattacharya , Ilya Shpitser , James M. Robins

We study the identification and estimation of statistical functionals of multivariate data missing non-monotonically and not-at-random, taking a semiparametric approach. Specifically, we assume that the missingness mechanism satisfies what…

Methodology · Statistics 2022-12-26 Daniel Malinsky , Ilya Shpitser , Eric J Tchetgen Tchetgen

This paper considers (partial) identification of a variety of counterfactual parameters in binary response models with possibly endogenous regressors. Our framework allows for nonseparable index functions with multi-dimensional latent…

Econometrics · Economics 2022-07-26 Jiaying Gu , Thomas M. Russell

It is "well known" that in linear models: (1) testable constraints on the marginal distribution of observed variables distinguish certain cases in which an unobserved cause jointly influences several observed variables; (2) the technique of…

Artificial Intelligence · Computer Science 2013-01-14 David Danks , Clark Glymour

A large variety of dynamical systems, such as chemical and biomolecular systems, can be seen as networks of nonlinear entities. Prediction, control, and identification of such nonlinear networks require knowledge of the state of the system.…

Optimization and Control · Mathematics 2018-06-27 Aleksandar Haber , Ferenc Molnar , Adilson E. Motter

There are things we know, things we know we don't know, and then there are things we don't know we don't know. In this paper we address the latter two issues in a Bayesian framework, introducing the notion of doubt to quantify the degree of…

Data Analysis, Statistics and Probability · Physics 2008-11-18 Glenn D Starkman , Roberto Trotta , Pascal M Vaudrevange

Pattern-mixture models provide a transparent approach for handling missing data, where the full-data distribution is factorized in a way that explicitly shows the parts that can be estimated from observed data alone, and the parts that…

Methodology · Statistics 2019-04-26 Yen-Chi Chen , Mauricio Sadinle

Latent class models have wide applications in social and biological sciences. In many applications, pre-specified restrictions are imposed on the parameter space of latent class models, through a design matrix, to reflect practitioners'…

Statistics Theory · Mathematics 2019-06-03 Yuqi Gu , Gongjun Xu

The increasing availability of experimental data has intensified interest in calibrating stochastic models, raising fundamental questions about parameter identifiability. Structural identifiability determines whether parameters can be…

Methodology · Statistics 2026-05-14 Arianna Ceccarelli , Alexander P. Browning , Ruth E. Baker

Parameter identifiability describes whether, for a given differential model, one can determine parameter values from model equations. Knowing global or local identifiability properties allows construction of better practical experiments to…

Mathematical Software · Computer Science 2021-07-02 Ilia Ilmer , Alexey Ovchinnikov , Gleb Pogudin

This study examines the characterization of binary star systems using Spectral Energy Distributions (SEDs), a technique increasingly essential with the rise of large-scale astronomical surveys. Binaries can emit flux at different regions of…

Solar and Stellar Astrophysics · Physics 2025-03-20 Vikrant V. Jadhav

A tacit assumption in classical linear regression problems is the full knowledge of the existing link between the covariates and responses. In Unlinked Linear Regression (ULR) this link is either partially or completely missing. While the…

Statistics Theory · Mathematics 2025-07-22 Fadoua Balabdaoui , Martin Slawski , Jonathan Steffani

Many important datasets contain samples that are missing one or more feature values. Maintaining the interpretability of machine learning models in the presence of such missing data is challenging. Singly or multiply imputing missing values…

Machine Learning · Computer Science 2026-02-10 Hayden McTavish , Jon Donnelly , Margo Seltzer , Cynthia Rudin

In this paper, we extend graph-based identification methods by allowing background knowledge in the form of non-zero parameter values. Such information could be obtained, for example, from a previously conducted randomized experiment, from…

Methodology · Statistics 2016-05-04 Bryant Chen , Judea Pearl , Elias Bareinboim

Most practical data science problems encounter missing data. A wide variety of solutions exist, each with strengths and weaknesses that depend upon the missingness-generating process. Here we develop a theoretical framework for training and…

Machine Learning · Computer Science 2022-11-15 Jahan C. Penny-Dimri , Christoph Bergmeir , Julian Smith

The condition of parameter identifiability is essential for the consistency of all estimators and is often challenging to prove. As a consequence, this condition is often assumed for simplicity although this may not be straightforward to…

Statistics Theory · Mathematics 2016-07-21 Stéphane Guerrier , Roberto Molinari

Missing data is a common problem in medical research, and is commonly addressed using multiple imputation. Although traditional imputation methods allow for valid statistical inference when data are missing at random (MAR), their…