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Although individual neurons and neural populations exhibit the phenomenon of representational drift, perceptual and behavioral outputs of many neural circuits can remain stable across time scales over which representational drift is…

The different active roles of neurons and astrocytes during neuronal activation are associated with the metabolic processes necessary to supply the energy needed for their respective tasks at rest and during neuronal activation. Metabolism,…

Tissues and Organs · Quantitative Biology 2022-11-07 Gideon Idumah , Erkki Somersalo , Daniela Calvetti

Convolutional Neural Networks (CNNs) have shown to be powerful classification tools in tasks that range from check reading to medical diagnosis, reaching close to human perception, and in some cases surpassing it. However, the problems to…

Distributed, Parallel, and Cluster Computing · Computer Science 2017-12-08 Jose Marques , Gabriel Falcao , Luís A. Alexandre

Neural processes are a family of models which use neural networks to directly parametrise a map from data sets to predictions. Directly parametrising this map enables the use of expressive neural networks in small-data problems where neural…

Machine Learning · Statistics 2024-08-20 Wessel P. Bruinsma

Diffusion models, a powerful and universal generative AI technology, have achieved tremendous success in computer vision, audio, reinforcement learning, and computational biology. In these applications, diffusion models provide flexible…

Machine Learning · Computer Science 2024-04-12 Minshuo Chen , Song Mei , Jianqing Fan , Mengdi Wang

Conventional diffusion models typically relies on a fixed forward process, which implicitly defines complex marginal distributions over latent variables. This can often complicate the reverse process' task in learning generative…

Machine Learning · Statistics 2025-06-10 Grigory Bartosh , Dmitry Vetrov , Christian A. Naesseth

Diffusion generative models have emerged as a powerful framework for addressing problems in structural biology and structure-based drug design. These models operate directly on 3D molecular structures. Due to the unfavorable scaling of…

Biomolecules · Quantitative Biology 2024-05-10 Ian Dunn , David Ryan Koes

Mathematical thinking is a fundamental aspect of human cognition. Cognitive scientists have investigated the mechanisms that underlie our ability to thinking geometrically and numerically, to take two prominent examples, and developmental…

Computer Vision and Pattern Recognition · Computer Science 2025-11-20 Zekun Wang , Sashank Varma

Generating visual instructions in a given context is essential for developing interactive world simulators. While prior works address this problem through either text-guided image manipulation or video prediction, these tasks are typically…

Computer Vision and Pattern Recognition · Computer Science 2025-11-25 Yujiang Pu , Zhanbo Huang , Vishnu Boddeti , Yu Kong

In contrast to conventional artificial neural networks, which are structurally static, we present two approaches for evolving small networks into larger ones during training. The first method employs an auxiliary weight that directly…

Machine Learning · Computer Science 2025-07-29 Anil Radhakrishnan , John F. Lindner , Scott T. Miller , Sudeshna Sinha , William L. Ditto

Recent development in computer processing power leads to new paradigms of how problems in many-body physics and especially polymer physics can be addressed. GPU parallel processors can be employed to generate millions of independent…

Soft Condensed Matter · Physics 2019-05-01 Marco Werner , Yachong Guo , Vladimir A. Baulin

Morphogenesis in the central nervous system has received intensive attention as elucidating fundamental mechanisms of morphogenesis will shed light on the physiology and pathophysiology of the developing central nervous system.…

Neurons and Cognition · Quantitative Biology 2022-07-25 Joseph Sutlive , Hamed Seyyedhosseinzadeh , Zheng Ao , Haning Xiu , Kun Gou , Feng Guo , Zi Chen

In this paper the authors extend [1] and provide more details of how the brain may act like a quantum computer. In particular, positing the difference between voltages on two axons as the environment for ions undergoing spatial…

Neurons and Cognition · Quantitative Biology 2022-11-15 Aman Chawla , Salvatore Domenic Morgera

The human brain undergoes rapid development during the third trimester of pregnancy. In this work, we model the neonatal development of the infant brain in this age range. As a basis, we use MR images of preterm- and term-birth neonates…

Image and Video Processing · Electrical Eng. & Systems 2024-08-19 Florentin Bieder , Paul Friedrich , Hélène Corbaz , Alicia Durrer , Julia Wolleb , Philippe C. Cattin

In this article, we review a class of neuro-mimetic computational models that we place under the label of spiking predictive coding. Specifically, we review the general framework of predictive processing in the context of neurons that emit…

Neurons and Cognition · Quantitative Biology 2024-09-10 Antony W. N'dri , William Gebhardt , Céline Teulière , Fleur Zeldenrust , Rajesh P. N. Rao , Jochen Triesch , Alexander Ororbia

The deep neural networks (DNNs) have been enormously successful in tasks that were hitherto in the human-only realm such as image recognition, and language translation. Owing to their success the DNNs are being explored for use in ever more…

Distributed, Parallel, and Cluster Computing · Computer Science 2019-06-20 Sanket Tavarageri , Srinivas Sridharan , Bharat Kaul

Functional brain graphs are often characterized with separate graph-theoretic or spectral descriptors, overlooking how these properties covary and partially overlap across brains and conditions. We anticipate that dense, weighted functional…

Neurons and Cognition · Quantitative Biology 2025-11-07 Subati Abulikemu , Tiago Azevedo , Michail Mamalakis , John Suckling

Current concepts of neural networks have emerged over two centuries of progress beginning with the neural doctrine to the idea of neural cell assemblies. Presently the model of neural networks involves distributed neural circuits of nodes,…

Neurons and Cognition · Quantitative Biology 2024-07-30 M. Ram Murty , A. Narayan Prasad

It is becoming increasingly appreciated that the signal transduction systems used by eukaryotic cells to achieve a variety of essential responses represent highly complex networks rather than simple linear pathways. While significant effort…

Molecular Networks · Quantitative Biology 2009-11-10 Kevin S. Brown , Colin C. Hill , Guillermo A. Calero , Kelvin H. Lee , James P. Sethna , Richard A. Cerione

The mechanisms of psychotic symptoms like hallucinations and delusions are often investigated in fully-formed illness, well after symptoms emerge. These investigations have yielded key insights, but are not well-positioned to reveal the…