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This review provides a critical overview of current developments on nanoelectronic biochemical sensors based on graphene. Composed of a single layer of conjugated carbon atoms, graphene has outstanding high carrier mobility and low…

Materials Science · Physics 2020-12-14 Xiaoyan Zhang , Qiushi Jing , Shen Ao , Grégory F. Schneider , Dmitry Kireev , Zhengjun Zhang , Wangyang Fu

We implemented a nanoelectronic interface between graphene field effect transistors (FETs) and soluble proteins. This enables production of bioelectronic devices that combine functionalities of the biomolecular and inorganic components. The…

Mesoscale and Nanoscale Physics · Physics 2015-06-03 Ye Lu , Mitchell B. Lerner , Zhengqing John Qi , Joseph J. Mitala , Jong Hsien Lim , Bohdana M. Discher , A. T. Charlie Johnson

This work presents an innovative magnetoelastic (ME) biosensor using graphene functionalized with the SARS-CoV-2 N protein for antibody detection via magnetoelastic resonance. Graphene was chosen for its biocompatibility and high surface…

Graphene field effect transistors (G-FETs) have appeared as suitable candidates for sensing charges and have thus attracted large interest for ion and chemical detections. In particular, their high sensitivity, chemical robustness,…

Mesoscale and Nanoscale Physics · Physics 2024-02-08 Océane Terral , Guillaume Audic , Arnaud Claudel , Justine Magnat , Aurélie Dupont , Christophe J. Moreau , Cécile Delacour

Current situation of COVID-19 demands a rapid, reliable, cost-effective, facile detection strategy to break the transmission chain and biosensor has emerged as a feasible solution for this purpose. Introduction of nanomaterials has…

Applied Physics · Physics 2020-12-11 Joydip Sengupta , Chaudhery Mustansar Hussain

Graphene has good mechanical properties including large Young's modulus, making it ideal for many resonant sensing applications. Nonetheless, the development of graphene based sensors has been limited due to difficulties in fabrication,…

Applied Physics · Physics 2023-07-11 Swapnil More , Akshay Naik

Graphene based nanomaterials have attracted significant attention for their potentials in biomedical and biotechnology applications in recent years, owing to the outstanding physical and chemical properties. However, the interaction…

Biomolecules · Quantitative Biology 2024-04-09 Jing Ye , Minzhi Fan , Xiaoyu Zhang , Shasha Lu , Mengyao Chai , Yunshan Zhang , Xiaoyu Zhao , Shuang Li , Diming Zhang

Infrared spectroscopy is the technique of choice for chemical identification of biomolecules through their vibrational fingerprints. However, infrared light interacts poorly with nanometric size molecules. Here, we exploit the unique…

Simpler and more rapid approaches for therapeutic drug-level monitoring are highly desirable to enable use at the point-of-care. We have developed an all-electronic approach for detection of the HIV drug tenofovir based on scalable…

Large-scale neural recording with high spatio-temporal resolution is essential for understanding information processing in brain, yet current neural interfaces fall far short of comprehensively capturing brain activity due to extremely high…

Scalable production of all-electronic DNA biosensors with high sensitivity and selectivity is a critical enabling step for research and applications associated with detection of DNA hybridization. We have developed a scalable and very…

Applied Physics · Physics 2017-08-31 Jinglei Ping , Ramya Vishnubhotla , Amey Vrudhula , A. T. Charlie Johnson

Biomonitoring wearable sensors based on two-dimensional nanomaterials have lately elicited keen research interest and potential for a new range of flexible nanoelectronic devices. Practical nanomaterial-based devices suited for real-world…

Nanoscale engineered materials combined with wearable wireless technologies can deliver a new level of health monitoring. A reduced graphene oxide-nylon composite material is developed and tested, demonstrating its usefulness as a material…

Oxygen (O2)-sensing matrices are promising tools for the live monitoring of extracellular O2 consumption levels in long-term cell cultures. In this study, ratiometric O2-sensing membranes were prepared by electrospinning, an easy, low-cost,…

The reliability of analysis is becoming increasingly important as point-of-care diagnostics are transitioning from single analyte detection towards multiplexed multianalyte detection. Multianalyte detection benefits greatly from…

Graphene, the atomically-thin honeycomb carbon lattice, is a highly conducting 2D material whose exposed electronic structure offers an ideal platform for sensing. Its biocompatible, flexible, and chemically inert nature associated to the…

Inspired by the dendritic integration and spiking operation of a biological neuron, flexible oxide-based neuron transistors gated by solid-state electrolyte films are fabricated on flexible plastic substrates for biochemical sensing…

Materials Science · Physics 2015-05-20 Ning Liu , Li Qiang Zhu , Ping Feng , Chang Jin Wan , Yang Hui Liu , Yi Shi , Qing Wan

The difficulty in determining the mass of a sample increases as its size diminishes. At the nanoscale, there are no direct methods for resolving the mass of single molecules or nanoparticles and so more sophisticated approaches based on…

Materials Science · Physics 2015-06-03 Stas M. Avdoshenko , Claudia Gomes da Rocha , Gianaurelio Cuniberti

Silicon nanochannel biological field effect transistors have been developed for glucose detection. The device is nanofabricated from a silicon-on-insulator wafer with a top-down approach and surface functionalized with glucose oxidase. The…

Biological Physics · Physics 2008-02-14 Xihua Wang , Yu Chen , Katherine A. Gibney , Shyamsunder Erramilli , Pritiraj Mohanty

Graphene Field-Effect Transistors (GFETs) are increasingly employed as biochemical sensors due to their exceptional electronic properties, surface sensitivity, and potential for miniaturization. A critical challenge in deploying GFETs is…

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