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Phylogenetic networks are a generalization of phylogenetic trees to leaf-labeled directed acyclic graphs that represent ancestral relationships between species whose past includes non-tree-like events such as hybridization and horizontal…

Combinatorics · Mathematics 2021-04-13 Janosch Döcker , Simone Linz , Charles Semple

Phylogenetic networks are used to study evolutionary relationships between species in biology. Such networks are often categorized into classes by their topological features, which stem from both biological and computational motivations. We…

Combinatorics · Mathematics 2020-04-17 Leo van Iersel , Remie Janssen , Mark Jones , Yukihiro Murakami , Norbert Zeh

Phylogenetic networks are used to represent the evolutionary history of species. Recently, the new class of orchard networks was introduced, which were later shown to be interpretable as trees with additional horizontal arcs. This makes the…

Combinatorics · Mathematics 2023-05-09 Leo van Iersel , Mark Jones , Esther Julien , Yukihiro Murakami

We propose the class of galled tree-child networks which is obtained as intersection of the classes of galled networks and tree-child networks. For the latter two classes, (asymptotic) counting results and stochastic results have been…

Combinatorics · Mathematics 2024-03-06 Yu-Sheng Chang , Michael Fuchs , Guan-Ru Yu

Geographic structure can affect patterns of genetic differentiation and speciation rates. In this article, we investigate the dynamics of genetic distances in a geographically structured metapopulation. We model the metapopulation as a…

Populations and Evolution · Quantitative Biology 2020-02-25 Verónica Miró Pina , Emmanuel Schertzer

Molecular phylogeny has focused mainly on improving models for the reconstruction of gene trees based on sequence alignments. Yet, most phylogeneticists seek to reveal the history of species. Although the histories of genes and species are…

Populations and Evolution · Quantitative Biology 2013-11-05 Gergely J. Szöllosi , Eric Tannier , Vincent Daubin , Bastien Boussau

Orthology and paralogy relations are often inferred by methods based on gene similarity, which usually yield a graph depicting the relationships between gene pairs. Such relation graphs are known to frequently contain errors, as they cannot…

Data Structures and Algorithms · Computer Science 2022-02-16 Mark Jones , Manuel Lafond , Celine Scornavacca

Orthologous genes, which arise through speciation, play a key role in comparative genomics and functional inference. In particular, graph-based methods allow for the inference of orthology estimates without prior knowledge of the underlying…

Populations and Evolution · Quantitative Biology 2025-02-14 Anna Lindeberg , Guillaume E. Scholz , Nicolas Wieseke , Marc Hellmuth

Gene regulatory networks (GRN) govern phenotypic adaptations and reflect the trade-offs between physiological responses and evolutionary adaptation that act at different time scales. To identify patterns of molecular function and genetic…

Network dynamics offers critical insights into the behavior and evolution of complex systems. Here, we focus on the topological dynamics of networks to explore a unique process for reducing the average distance: topological compression. The…

General Topology · Mathematics 2025-08-07 Jian-Hui Li , Zu-Guo Yu , Yu-Chu Tian

We consider a model for the formation of a river network in which erosion process plays a role only at the initial stage. Once a global connectivity is achieved, no further evolution takes place. In spite of this, the network reproduces…

Condensed Matter · Physics 2009-10-28 S. S. Manna , B. Subramanian

The minimal number of rooted subtree prune and regraft (rSPR) operations needed to transform one phylogenetic tree into another one induces a metric on phylogenetic trees - the rSPR-distance. The rSPR-distance between two phylogenetic trees…

Combinatorics · Mathematics 2023-06-22 Jonathan Klawitter

A classical result, fundamental to evolutionary biology, states that an edge-weighted tree $T$ with leaf set $X$, positive edge weights, and no vertices of degree 2 can be uniquely reconstructed from the set of leaf-to-leaf distances…

Populations and Evolution · Quantitative Biology 2011-07-15 A. W. M. Dress , K. T. Huber , M. Steel

In evolutionary biology, phylogenetic networks are constructed to represent the evolution of species in which reticulate events are thought to have occurred, such as recombination and hybridization. It is therefore useful to have…

Populations and Evolution · Quantitative Biology 2017-03-16 Vincent Moulton , James Oldman , Taoyang Wu

Recent work has established clear links between the generalization performance of trained neural networks and the geometry of their loss landscape near the local minima to which they converge. This suggests that qualitative and quantitative…

Machine Learning · Computer Science 2022-01-28 Stefan Horoi , Jessie Huang , Bastian Rieck , Guillaume Lajoie , Guy Wolf , Smita Krishnaswamy

Semi-directed phylogenetic networks have recently emerged as a class of phylogenetic networks sitting between rooted (directed) and unrooted (undirected) phylogenetic networks as they contain both directed as well as undirected edges. While…

Combinatorics · Mathematics 2023-01-27 Simone Linz , Kristina Wicke

The normalized edit distance is one of the distances derived from the edit distance. It is useful in some applications because it takes into account the lengths of the two strings compared. The normalized edit distance is not defined in…

Neural and Evolutionary Computing · Computer Science 2013-12-09 Muhammad Marwan Muhammad Fuad

In many interesting cases the reconstruction of a correct phylogeny is blurred by high mutation rates and/or horizontal transfer events. As a consequence a divergence arises between the true evolutionary distances and the differences…

Populations and Evolution · Quantitative Biology 2010-02-08 F. Tria , E. Caglioti , V. Loreto , A. Pagnani

The time process of transport on randomly evolving trees is investigated. By introducing the notions of living and dead nodes a model of random tree evolution is constructed which describes the spreading in time of objects corresponding to…

Statistical Mechanics · Physics 2009-11-11 L. Pal

Rooted binary phylogenetic networks are extensions of rooted binary trees, adding reticulation nodes that are designed to represent evolutionary processes that involve hybridization events. Enumerative combinatorics studies have counted…